Reviewed, UniProtKB/Swiss-Prot Q97CK6 (COMB_THEVO)

Names and origin

Protein names

Recommended name:
    Probable 2-phosphosulfolactate phosphatase
    EC=3.1.3.71

Gene names

Name:	comB
Ordered Locus Names:	TV0095
ORF Names:	TVG0100132

Organism

Thermoplasma volcanium [Complete proteome] [HAMAP]

Taxonomic identifier

50339 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Thermoplasmata › Thermoplasmatales › Thermoplasmataceae › Thermoplasma

Protein attributes

Sequence length	212 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	(2R)-2-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate + phosphate. HAMAP MF_00490
Cofactor	Magnesium By similarity.
Sequence similarities	Belongs to the comB family.

Ontologies

Keywords
Ligand	Magnesium
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	coenzyme M biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	2-phosphosulfolactate phosphatase activity Inferred from electronic annotation. Source: HAMAP magnesium ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 212	212	Probable 2-phosphosulfolactate phosphatase HAMAP MF_00490		PRO_0000081462

Sequences

	Sequence		Length	Mass (Da)
	Q97CK6-1 [UniParc]. Last modified October 1, 2001. Version 1. Checksum: D67465756C8C4A29	FASTA	212	23,936
	10 20 30 40 50 60 MIRIADGRKE ENWSSINIII DIFRSTTTIP VILSRGARYI VPFKDVTSAL NFKRKNKNVV 70 80 90 100 110 120 LIGEKYGIKP PFFDYDNSPA QIINADLEGK IIAFTSTNGM YVLSRIKRGR ILFSSLVNMS 130 140 150 160 170 180 ATIKKVKGKD DILVVPSNRP IGKAVEDNIF AEMLKLALEG KNYDREILVN RIRETKENTV 190 200 210 VSISTQDLEI CLKLDLLDCV PEYIEGKIVN DP

References

[1]

"Archaeal adaptation to higher temperatures revealed by genomic sequence of Thermoplasma volcanium." Kawashima T., Amano N., Koike H., Makino S., Higuchi S., Kawashima-Ohya Y., Watanabe K., Yamazaki M., Kanehori K., Kawamoto T., Nunoshiba T., Yamamoto Y., Aramaki H., Makino K., Suzuki M. Proc. Natl. Acad. Sci. U.S.A. 97:14257-14262(2000) [PubMed: 11121031] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51530 / DSM 4299 / IFO 15438 / JCM 9571 / GSS1.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000011 Genomic DNA. Translation: BAB59237.1.
RefSeq	NP_110615.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	1441582.
GenomeReviews	Gene locus TV0095 in contig BA000011_GR.
KEGG	tvo:TVN0096.
NMPDR	fig|273116.1.peg.96.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q97CK6.
OMA	Q97CK6. RSTTTIP.
Enzyme and pathway databases
BRENDA	3.1.3.71. 256346.
Family and domain databases
HAMAP	MF_00490. [Tree]
InterPro	IPR005238. 2-PSlactate_phosphatase. [Graphical view]
Gene3D	G3DSA:3.90.1560.10. 2-PSlactate_phosphatase. 1 hit.
Pfam	PF04029. 2-ph_phosp. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

COMB_THEVO

Accession

Primary (citable) accession number: Q97CK6

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 5, 2001
Last sequence update:	October 1, 2001
Last modified:	May 5, 2009
This is version 39 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)