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Q97CD7

- PUR5_THEVO

UniProt

Q97CD7 - PUR5_THEVO

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Protein

Phosphoribosylformylglycinamidine cyclo-ligase

Gene

purM

Organism
Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoribosylformylglycinamidine cyclo-ligase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. 'de novo' IMP biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Purine biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciTVOL273116:GC31-169-MONOMER.
UniPathwayiUPA00074; UER00129.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoribosylformylglycinamidine cyclo-ligaseUniRule annotation (EC:6.3.3.1UniRule annotation)
Alternative name(s):
AIR synthaseUniRule annotation
AIRSUniRule annotation
Phosphoribosyl-aminoimidazole synthetaseUniRule annotation
Gene namesi
Name:purMUniRule annotation
Ordered Locus Names:TV0165
ORF Names:TVG0175535
OrganismiThermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1)
Taxonomic identifieri273116 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermoplasmataThermoplasmatalesThermoplasmataceaeThermoplasma
ProteomesiUP000001017: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 338338Phosphoribosylformylglycinamidine cyclo-ligasePRO_0000148292Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi273116.TVN0164.

Structurei

3D structure databases

ProteinModelPortaliQ97CD7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the AIR synthase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0150.
KOiK01933.
OMAiVIGKIEH.

Family and domain databases

Gene3Di3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPiMF_00741. AIRS.
InterProiIPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view]
PfamiPF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view]
SUPFAMiSSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsiTIGR00878. purM. 1 hit.

Sequencei

Sequence statusi: Complete.

Q97CD7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MPEVKDGIID RKMQGEFVSS FIRQLKFHRE DFKNIGYIGG FTSLIDMGNF
60 70 80 90 100
ALSFNNDGVG TKTMIAEQAN KYDTLGIDCV AMNVNDAITV GSEPIAMVDY
110 120 130 140 150
LAVRDLNEDI AKQLGNGFNV GAQIANISIV GGETAVVPEI VNHIDVSGAV
160 170 180 190 200
IGIVQKNQII TGANIKEGDV IIGLGSSGLH SNGFTTVRKI ISDNEINLFD
210 220 230 240 250
NFPGESKKTY EVLLEPTRIY VREILDVMGI IQIKGMANIT GGGFKNITRM
260 270 280 290 300
KDMKYVIDDP MEPQNVFVRL MELGNLNYKQ MYEIFNMGTG FVVVIGEDDK
310 320 330
IDFINTLKNR VPLKVIGHVE NGTGVEIPKY SVSLMGYY
Length:338
Mass (Da):37,183
Last modified:October 1, 2001 - v1
Checksum:i0AC488696971DEF5
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000011 Genomic DNA. Translation: BAB59307.1.
RefSeqiNP_110683.1. NC_002689.2.

Genome annotation databases

EnsemblBacteriaiBAB59307; BAB59307; BAB59307.
GeneIDi1441650.
KEGGitvo:TVN0164.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000011 Genomic DNA. Translation: BAB59307.1 .
RefSeqi NP_110683.1. NC_002689.2.

3D structure databases

ProteinModelPortali Q97CD7.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 273116.TVN0164.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAB59307 ; BAB59307 ; BAB59307 .
GeneIDi 1441650.
KEGGi tvo:TVN0164.

Phylogenomic databases

eggNOGi COG0150.
KOi K01933.
OMAi VIGKIEH.

Enzyme and pathway databases

UniPathwayi UPA00074 ; UER00129 .
BioCyci TVOL273116:GC31-169-MONOMER.

Family and domain databases

Gene3Di 3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPi MF_00741. AIRS.
InterProi IPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view ]
Pfami PF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view ]
SUPFAMi SSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsi TIGR00878. purM. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1.

Entry informationi

Entry nameiPUR5_THEVO
AccessioniPrimary (citable) accession number: Q97CD7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 28, 2003
Last sequence update: October 1, 2001
Last modified: October 29, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3