Q97C23 (RNP4_THEVO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribonuclease P protein component 4
Short name=RNase P component 4
EC=3.1.26.5

Gene names

Name:	rnp4
Ordered Locus Names:	TV0282
ORF Names:	TVG0293828

Organism

Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1) [Complete proteome] [HAMAP]

Taxonomic identifier

273116 [NCBI]

Taxonomic lineage

cellular organisms › Archaea › Euryarchaeota › Thermoplasmata › Thermoplasmatales › Thermoplasmataceae › Thermoplasma › Thermoplasma volcanium

Protein attributes

Sequence length	98 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends By similarity. HAMAP-Rule MF_00757
Catalytic activity	Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor. HAMAP-Rule MF_00757
Subunit structure	Consists of a catalytic RNA component and at least 4 protein subunits Potential.
Sequence similarities	Belongs to the eukaryotic/archaeal RNase P protein component 4 family.
Sequence caution	The sequence BAB59424.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Biological process	tRNA processing
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	tRNA 5'-leader removal Inferred from electronic annotation. Source: HAMAP
Molecular_function	ribonuclease P activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 98	98	Ribonuclease P protein component 4 HAMAP-Rule MF_00757		PRO_0000153866

Sequences

	Sequence		Length	Mass (Da)
	Q97C23 [UniParc]. Last modified July 5, 2004. Version 2. Checksum: D4F5F038CD090DA5	FASTA	98	11,963
	10 20 30 40 50 60 MSNNNYERLI TKKDVYRVAN ERLYYLFSLA FQTGDERYID LMERIGRRMD ITLPQDIKRM 70 80 90 YCKKCKKPYK NVRVRLKKNV ITVTCLECGD IRRFQINR

References

[1]

"Archaeal adaptation to higher temperatures revealed by genomic sequence of Thermoplasma volcanium." Kawashima T., Amano N., Koike H., Makino S., Higuchi S., Kawashima-Ohya Y., Watanabe K., Yamazaki M., Kanehori K., Kawamoto T., Nunoshiba T., Yamamoto Y., Aramaki H., Makino K., Suzuki M. Proc. Natl. Acad. Sci. U.S.A. 97:14257-14262(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000011 Genomic DNA. Translation: BAB59424.1. Different initiation.
RefSeq	NP_110798.1. NC_002689.2.
3D structure databases
ProteinModelPortal	Q97C23.
ModBase	Search...
Protein-protein interaction databases
STRING	273116.TVN0279.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAB59424; BAB59424; BAB59424.
GeneID	1440795.
KEGG	tvo:TVN0279.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG2023.
KO	K03540.
OMA	IDLMERI.
ProtClustDB	CLSK227722.
Family and domain databases
HAMAP	MF_00757. RNase_P_4.
InterPro	IPR016432. RNase_P_comp-4. IPR007175. Rpr2. [Graphical view]
Pfam	PF04032. Rpr2. 1 hit. [Graphical view]
PIRSF	PIRSF004878. RNase_P_4. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RNP4_THEVO

Accession

Primary (citable) accession number: Q97C23

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 5, 2004
Last sequence update:	July 5, 2004
Last modified:	May 1, 2013
This is version 44 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program