Reviewed, UniProtKB/Swiss-Prot Q97AN7 (PDAD_THEVO)

Names and origin

Protein names

Recommended name:
    Pyruvoyl-dependent arginine decarboxylase
      Short name=PvlArgDC
    EC=4.1.1.19
Cleaved into the following 2 chains:
    1- Recommended name:
            Pyruvoyl-dependent arginine decarboxylase subunit beta
    2- Recommended name:
            Pyruvoyl-dependent arginine decarboxylase subunit alpha

Gene names

Name:	pdaD
Ordered Locus Names:	TV0773
ORF Names:	TVG0778593

Organism

Thermoplasma volcanium [Complete proteome] [HAMAP]

Taxonomic identifier

50339 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Thermoplasmata › Thermoplasmatales › Thermoplasmataceae › Thermoplasma

Protein attributes

Sequence length	182 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	L-arginine = agmatine + CO2. HAMAP MF_01404
Cofactor	Pyruvoyl group By similarity.
Sequence similarities	Belongs to the pdaD family.

Ontologies

Keywords
Ligand	Pyruvate
Molecular function	Decarboxylase Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arginine catabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	arginine decarboxylase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 43	43	Pyruvoyl-dependent arginine decarboxylase subunit beta By similarity		PRO_0000023338
	Chain	44 – 182	139	Pyruvoyl-dependent arginine decarboxylase subunit alpha By similarity		PRO_0000023339
Sites
	Site	43 – 44	2	Cleavage (non-hydrolytic) By similarity
Amino acid modifications
	Modified residue	44	1	Pyruvic acid (Ser) By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q97AN7-1 [UniParc]. Last modified October 1, 2001. Version 1. Checksum: C6560128EFBF6DAF	FASTA	182	19,824
	10 20 30 40 50 60 MSGFVPSEIF FTRGVGRGET QLESFEAALR DAGIAQFNLS SISSIFPPHA KMVSKEEGLK 70 80 90 100 110 120 KLSPGQILFT VLARNTSNEL NRMISAAIGY AIPRDKSKWG YLSEHHSFGE TEKVAGSFAE 130 140 150 160 170 180 KLAAEMLSST FGSTSQLIYD KEKEEYVLED KILTTGNISA TAVVLSHDEW TTVVAAAVLI VE

References

[1]

"Archaeal adaptation to higher temperatures revealed by genomic sequence of Thermoplasma volcanium." Kawashima T., Amano N., Koike H., Makino S., Higuchi S., Kawashima-Ohya Y., Watanabe K., Yamazaki M., Kanehori K., Kawamoto T., Nunoshiba T., Yamamoto Y., Aramaki H., Makino K., Suzuki M. Proc. Natl. Acad. Sci. U.S.A. 97:14257-14262(2000) [PubMed: 11121031] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51530 / DSM 4299 / IFO 15438 / JCM 9571 / GSS1.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BA000011 Genomic DNA. Translation: BAB59915.1.
RefSeq	NP_111281.1.
3D structure databases
HSSP	HSSP built from PDB template 1N2M based on UniProtKB Q57764.
ModBase	Search...
Genome annotation databases
GeneID	1441868.
GenomeReviews	Gene locus TV0773 in contig BA000011_GR.
KEGG	tvo:TVN0762.
NMPDR	fig|273116.1.peg.762.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q97AN7.
OMA	YKMSGKI.
Enzyme and pathway databases
BRENDA	4.1.1.19. 256346.
Family and domain databases
HAMAP	MF_01404. [Tree]
InterPro	IPR016105. Pyr-dep_his/arg-deCO2ase_sand. IPR002724. Pyruvoyl-dep_arg_deCO2ase. [Graphical view]
Gene3D	G3DSA:3.50.20.10. Pyr-dep_his/arg-deCO2ase_sand. 1 hit.
Pfam	PF01862. PvlArgDC. 1 hit. [Graphical view]
PIRSF	PIRSF005216. Pyruvoyl-dep_arg_deCO2ase. 1 hit.
ProDom	PD010449. DUF44. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00286. PvlArgDC. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PDAD_THEVO

Accession

Primary (citable) accession number: Q97AN7

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 11, 2002
Last sequence update:	October 1, 2001
Last modified:	November 3, 2009
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)