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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei156GTPUniRule annotation1
Binding sitei160GTPUniRule annotation1
Binding sitei203GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi125 – 127GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotation
ORF Names:TVG0806423Imported
OrganismiThermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1)Imported
Taxonomic identifieri273116 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermoplasmataThermoplasmatalesThermoplasmataceaeThermoplasma
Proteomesi
  • UP000001017 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation
  • Note: Assembles at midcell at the inner surface of the cytoplasmic membrane.UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.UniRule annotation

Protein-protein interaction databases

STRINGi273116.TVN0792.

Structurei

3D structure databases

ProteinModelPortaliQ97AK4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini30 – 221TubulinInterPro annotationAdd BLAST192
Domaini223 – 342Tubulin_CInterPro annotationAdd BLAST120

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG02201. Archaea.
COG0206. LUCA.
KOiK03531.
OMAiARDATIM.
OrthoDBiPOG093Z0942.

Family and domain databases

CDDicd02201. FtsZ_type1. 1 hit.
Gene3Di3.30.1330.20. 1 hit.
3.40.50.1440. 1 hit.
HAMAPiMF_00909. FtsZ. 1 hit.
InterProiView protein in InterPro
IPR000158. Cell_div_FtsZ.
IPR024757. FtsZ_C.
IPR008280. Tub_FtsZ_C.
IPR018316. Tubulin/FtsZ_2-layer-sand-dom.
IPR003008. Tubulin_FtsZ_GTPase.
PfamiView protein in Pfam
PF12327. FtsZ_C. 1 hit.
PF00091. Tubulin. 1 hit.
PRINTSiPR00423. CELLDVISFTSZ.
SMARTiView protein in SMART
SM00864. Tubulin. 1 hit.
SM00865. Tubulin_C. 1 hit.
SUPFAMiSSF52490. SSF52490. 1 hit.
SSF55307. SSF55307. 1 hit.
TIGRFAMsiTIGR00065. ftsZ. 1 hit.

Sequencei

Sequence statusi: Complete.

Q97AK4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MCMDNSNNSE EDIWTNDEKL QKIIEELNFR IKVFGFGGSG SNTINRLMRE
60 70 80 90 100
NLSGVKLIAC NTDAAHLLRI RAHSKILLGK NLTRGLGAGA DPSVGEMAAK
110 120 130 140 150
ESESEILKQI DETSIVFITA GLGGGTGTGA APYVAKLAKD RGALTISFAT
160 170 180 190 200
LPFSTEGFVR MKNAYEGVRK LVKNSDAAVI IPNDKLIEKF NDVPVYKAFK
210 220 230 240 250
FEDEVIATGI KGITDLIMST GTINLDFNDL RKVMKDAGYS AIGMGSSSQA
260 270 280 290 300
VNDRIVEALE KALDSPFMDV DISKAKGAII NVTGGRDLQL QEAQQAADIL
310 320 330 340
KKKIARDATI MWGTVVDESI RSSVKILVIV AGVKPNFKFE PGIEEVG
Length:347
Mass (Da):37,421
Last modified:October 1, 2001 - v1
Checksum:i5CC382D1BFA82331
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000011 Genomic DNA. Translation: BAB59948.1.

Genome annotation databases

EnsemblBacteriaiBAB59948; BAB59948; BAB59948.
KEGGitvo:TVG0806423.

Similar proteinsi

Entry informationi

Entry nameiQ97AK4_THEVO
AccessioniPrimary (citable) accession number: Q97AK4
Entry historyiIntegrated into UniProtKB/TrEMBL: October 1, 2001
Last sequence update: October 1, 2001
Last modified: September 27, 2017
This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.UniRule annotation

Keywords - Technical termi

Complete proteomeImported