Q979N7 (TDXH_THEVO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable peroxiredoxin
EC=1.11.1.15

Gene names

Ordered Locus Names:	TV1123
ORF Names:	TVG1154375

Organism

Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1) [Complete proteome] [HAMAP]

Taxonomic identifier

273116 [NCBI]

Taxonomic lineage

cellular organisms › Archaea › Euryarchaeota › Thermoplasmata › Thermoplasmatales › Thermoplasmataceae › Thermoplasma › Thermoplasma volcanium

Protein attributes

Sequence length	203 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	2 R'-SH + ROOH = R'-S-S-R' + H2O + ROH. HAMAP-Rule MF_00401
Sequence similarities	Belongs to the AhpC/TSA family. TDXH subfamily. Contains 1 thioredoxin domain.

Ontologies

Keywords
Domain	Redox-active center
Molecular function	Antioxidant Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	cell redox homeostasis Inferred from electronic annotation. Source: HAMAP
Molecular_function	antioxidant activity Inferred from electronic annotation. Source: UniProtKB-KW peroxiredoxin activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 203	203	Probable peroxiredoxin HAMAP-Rule MF_00401		PRO_0000135174
Regions
	Domain	3 – 156	154	Thioredoxin
Sites
	Active site	44	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q979N7 [UniParc]. Last modified October 1, 2001. Version 1. Checksum: 9CE5C7536380BD9A	FASTA	203	23,252
	10 20 30 40 50 60 MPVVLGQKAP DFTVNTSKGP ITLSNYRGKW VLLFSHPGDF TPVCTTEFIA FTERYEDFQK 70 80 90 100 110 120 LGVELIGLSI DSVFSHIAWI RDIKEHFGID IPFPIIADID KEVAREYNLI DEKSGATVRG 130 140 150 160 170 180 VFIIDPNQIV RWMIYYPAET GRNIEEIIRV IKALQFNWDR KLATPANWQP GQEGIEPAPT 190 200 TVDSSFKRDN EQGVKTWYLK FVK

References

[1]

"Archaeal adaptation to higher temperatures revealed by genomic sequence of Thermoplasma volcanium." Kawashima T., Amano N., Koike H., Makino S., Higuchi S., Kawashima-Ohya Y., Watanabe K., Yamazaki M., Kanehori K., Kawamoto T., Nunoshiba T., Yamamoto Y., Aramaki H., Makino K., Suzuki M. Proc. Natl. Acad. Sci. U.S.A. 97:14257-14262(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000011 Genomic DNA. Translation: BAB60265.1.
RefSeq	NP_111618.1. NC_002689.2.
3D structure databases
ProteinModelPortal	Q979N7.
ModBase	Search...
Protein-protein interaction databases
STRING	273116.TVN1099.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAB60265; BAB60265; BAB60265.
GeneID	1441239.
KEGG	tvo:TVN1099.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0450.
KO	K03386.
OMA	TEFIAFT.
ProtClustDB	PRK13190.
Family and domain databases
Gene3D	3.40.30.10. 1 hit.
HAMAP	MF_00401. Peroxiredoxin.
InterPro	IPR000866. AhpC/TSA. IPR024706. Peroxiredoxin_AhpC-typ. IPR019479. Peroxiredoxin_C. IPR022915. Peroxiredoxin_TDXH_put. IPR012336. Thioredoxin-like_fold. [Graphical view]
Pfam	PF10417. 1-cysPrx_C. 1 hit. PF00578. AhpC-TSA. 1 hit. [Graphical view]
PIRSF	PIRSF000239. AHPC. 1 hit.
SUPFAM	SSF52833. Thiordxn-like_fd. 1 hit.
PROSITE	PS51352. THIOREDOXIN_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TDXH_THEVO

Accession

Primary (citable) accession number: Q979N7

Entry history

Integrated into UniProtKB/Swiss-Prot:	October 10, 2002
Last sequence update:	October 1, 2001
Last modified:	May 1, 2013
This is version 65 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program