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Q979N7 (TDXH_THEVO) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Probable peroxiredoxin

EC=1.11.1.15
Gene names
Ordered Locus Names:TV1123
ORF Names:TVG1154375
OrganismThermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1) [Complete proteome] [HAMAP]
Taxonomic identifier273116 [NCBI]
Taxonomic lineageArchaeaEuryarchaeotaThermoplasmataThermoplasmatalesThermoplasmataceaeThermoplasma

Protein attributes

Sequence length203 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

2 R'-SH + ROOH = R'-S-S-R' + H2O + ROH. HAMAP-Rule MF_00401

Sequence similarities

Belongs to the AhpC/TSA family. TDXH subfamily.

Contains 1 thioredoxin domain.

Ontologies

Keywords
   DomainRedox-active center
   Molecular functionAntioxidant
Oxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processcell redox homeostasis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionantioxidant activity

Inferred from electronic annotation. Source: UniProtKB-KW

peroxiredoxin activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 203203Probable peroxiredoxin HAMAP-Rule MF_00401
PRO_0000135174

Regions

Domain3 – 156154Thioredoxin

Sites

Active site441 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q979N7 [UniParc].

Last modified October 1, 2001. Version 1.
Checksum: 9CE5C7536380BD9A

FASTA20323,252
        10         20         30         40         50         60 
MPVVLGQKAP DFTVNTSKGP ITLSNYRGKW VLLFSHPGDF TPVCTTEFIA FTERYEDFQK 

        70         80         90        100        110        120 
LGVELIGLSI DSVFSHIAWI RDIKEHFGID IPFPIIADID KEVAREYNLI DEKSGATVRG 

       130        140        150        160        170        180 
VFIIDPNQIV RWMIYYPAET GRNIEEIIRV IKALQFNWDR KLATPANWQP GQEGIEPAPT 

       190        200 
TVDSSFKRDN EQGVKTWYLK FVK 

« Hide

References

[1]"Archaeal adaptation to higher temperatures revealed by genomic sequence of Thermoplasma volcanium."
Kawashima T., Amano N., Koike H., Makino S., Higuchi S., Kawashima-Ohya Y., Watanabe K., Yamazaki M., Kanehori K., Kawamoto T., Nunoshiba T., Yamamoto Y., Aramaki H., Makino K., Suzuki M.
Proc. Natl. Acad. Sci. U.S.A. 97:14257-14262(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000011 Genomic DNA. Translation: BAB60265.1.
RefSeqNP_111618.1. NC_002689.2.

3D structure databases

ProteinModelPortalQ979N7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING273116.TVN1099.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAB60265; BAB60265; BAB60265.
GeneID1441239.
KEGGtvo:TVN1099.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0450.
KOK03386.
OMASHYSHIA.
ProtClustDBPRK13190.

Enzyme and pathway databases

BioCycTVOL273116:GC31-1134-MONOMER.

Family and domain databases

Gene3D3.40.30.10. 1 hit.
HAMAPMF_00401. Peroxiredoxin.
InterProIPR000866. AhpC/TSA.
IPR024706. Peroxiredoxin_AhpC-typ.
IPR019479. Peroxiredoxin_C.
IPR022915. Peroxiredoxin_TDXH_put.
IPR012336. Thioredoxin-like_fold.
[Graphical view]
PfamPF10417. 1-cysPrx_C. 1 hit.
PF00578. AhpC-TSA. 1 hit.
[Graphical view]
PIRSFPIRSF000239. AHPC. 1 hit.
SUPFAMSSF52833. SSF52833. 1 hit.
PROSITEPS51352. THIOREDOXIN_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameTDXH_THEVO
AccessionPrimary (citable) accession number: Q979N7
Entry history
Integrated into UniProtKB/Swiss-Prot: October 10, 2002
Last sequence update: October 1, 2001
Last modified: February 19, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families