Q979G8 (Q979G8_THEVO) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
3-hydroxy-3-methylglutaryl-coenzyme A reductase EMBL BAB60335.1

Gene names

Ordered Locus Names:

TV1193

Organism

Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1) [Complete proteome] [HAMAP]

Taxonomic identifier

273116 [NCBI]

Taxonomic lineage

Archaea › Euryarchaeota › Thermoplasmata › Thermoplasmatales › Thermoplasmataceae › Thermoplasma

Protein attributes

Sequence length	419 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the HMG-CoA reductase family. RuleBase RU004268

Ontologies

Keywords
Molecular function	Oxidoreductase RuleBase RU004269
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	coenzyme A metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	coenzyme binding Inferred from electronic annotation. Source: InterPro hydroxymethylglutaryl-CoA reductase (NADPH) activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q979G8 [UniParc]. Last modified October 1, 2001. Version 1. Checksum: 7356064AF07849F4	FASTA	419	45,244
	10 20 30 40 50 60 MVSSEVSGFY KMTVDERLNF VKEFSRLSDD DIRILRTNGS LAIDKADKII ENVITTIEMP 70 80 90 100 110 120 LGIAVNFLIN GKDYLIPMAI EEPSVVAAAS NAAKVARKSG GFNAYATEPV MIGEIQVLGI 130 140 150 160 170 180 DSLYLAKMNI LRDKSRILEL ANTRSKTLSS LGAGAKDIEV NVYERPHRML IVHLIVDVRD 190 200 210 220 230 240 AMGANVVNSM CEYVAPEIEK ITGGRVNLRI LSNLTKYRVA YASAVFSKDI IGKEAVDNIV 250 260 270 280 290 300 EAYRMAVVDI YRASTNNKGI MNGIDAVLVA TMNDWRAAEA NAHSYAALEG YGPLAKYEKN 310 320 330 340 350 360 SNGDLVGTIE IPIAVGTVGG TTGSIDKARI ARKILGVSNA TEFAGVLAAV GLAQNFSAVR 370 380 390 400 410 ALATEGIQRG HMELHARNLA LSAGASPEEV DSVVNEMISS KEITMSNAIK ILEKMRKTK

References

[1]

"Archaeal adaptation to higher temperatures revealed by genomic sequence of Thermoplasma volcanium." Kawashima T., Amano N., Koike H., Makino S., Higuchi S., Kawashima-Ohya Y., Watanabe K., Yamazaki M., Kanehori K., Kawamoto T., Nunoshiba T., Yamamoto Y., Aramaki H., Makino K., Suzuki M. Proc. Natl. Acad. Sci. U.S.A. 97:14257-14262(2000) [PubMed: 11121031] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000011 Genomic DNA. Translation: BAB60335.1.
RefSeq	NP_111687.1. NC_002689.2.
3D structure databases
HSSP	HSSP built from PDB template 1QAY based on UniProtKB P13702.
ProteinModelPortal	Q979G8.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1441308.
GenomeReviews	Gene locus TV1193 in contig BA000011_GR.
KEGG	tvo:TVN1168.
NMPDR	fig|273116.1.peg.1168.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG477902.
OMA	NNKGIMN.
ProtClustDB	CLSK246007.
Family and domain databases
InterPro	IPR002202. HMG_CoA_Rdtase. IPR004553. HMG_CoA_Rdtase_bac-typ. IPR023074. HMG_CoA_Rdtase_cat. IPR023076. HMG_CoA_Rdtase_CS. IPR009023. HMG_CoA_Rdtase_NAD(P)-bd. IPR009029. HMG_CoA_Rdtase_sub-bd. [Graphical view]
Gene3D	G3DSA:3.30.70.420. G3DSA:3.30.70.420. 1 hit. G3DSA:3.90.770.10. HMG-CoA_red. 2 hits.
KO	K00054.
Pfam	PF00368. HMG-CoA_red. 1 hit. [Graphical view]
PRINTS	PR00071. HMGCOARDTASE.
SUPFAM	SSF55035. HMG_CoA_NAD_bind. 1 hit. SSF56542. HMG_CoA_sub_bind. 1 hit.
TIGRFAMs	TIGR00532. HMG_CoA_R_NAD. 1 hit.
PROSITE	PS00066. HMG_COA_REDUCTASE_1. 1 hit. PS01192. HMG_COA_REDUCTASE_3. 1 hit. PS50065. HMG_COA_REDUCTASE_4. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q979G8_THEVO

Accession

Primary (citable) accession number: Q979G8

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2001
Last sequence update:	October 1, 2001
Last modified:	November 16, 2011
This is version 61 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)