SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q978F3

- PGMI_THEVO

UniProt

Q978F3 - PGMI_THEVO

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Bifunctional phosphoglucose/phosphomannose isomerase
Gene
TV1464, TVG1514630
Organism
Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the isomerization of both glucose 6-phosphate and epimeric mannose 6-phosphate at a similar catalytic efficiency By similarity.

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.
D-mannose 6-phosphate = D-fructose 6-phosphate.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei196 – 1961Proton acceptor By similarity
Active sitei212 – 2121Proton donor By similarity
Active sitei300 – 3001Proton acceptor By similarity

GO - Molecular functioni

  1. carbohydrate binding Source: InterPro
  2. glucose-6-phosphate isomerase activity Source: UniProtKB-EC
  3. mannose-6-phosphate isomerase activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Enzyme and pathway databases

BioCyciTVOL273116:GC31-1487-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Bifunctional phosphoglucose/phosphomannose isomerase
Alternative name(s):
Glucose-6-phosphate isomerase (EC:5.3.1.9)
Short name:
GPI
Mannose-6-phosphate isomerase (EC:5.3.1.8)
Phosphoglucose isomerase
Short name:
PGI
Phosphomannose isomerase
Short name:
PMI
Gene namesi
Ordered Locus Names:TV1464
ORF Names:TVG1514630
OrganismiThermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1)
Taxonomic identifieri273116 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermoplasmataThermoplasmatalesThermoplasmataceaeThermoplasma
ProteomesiUP000001017: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 304304Bifunctional phosphoglucose/phosphomannose isomerase
PRO_0000227798Add
BLAST

Interactioni

Subunit structurei

Homodimer By similarity.

Protein-protein interaction databases

STRINGi273116.TVN1438.

Structurei

3D structure databases

ProteinModelPortaliQ978F3.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini16 – 147132SIS
Add
BLAST

Sequence similaritiesi

Belongs to the PGI/PMI family.
Contains 1 SIS domain.

Phylogenomic databases

eggNOGiCOG0166.
KOiK15916.
OMAiIAERWKG.

Family and domain databases

InterProiIPR011857. Glu6P/Mann6P_isomerase.
IPR019490. Glu6P/Mann6P_isomerase_C.
IPR001347. SIS.
[Graphical view]
PfamiPF10432. bact-PGI_C. 1 hit.
PF01380. SIS. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02128. G6PI_arch. 1 hit.
PROSITEiPS51464. SIS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q978F3-1 [UniParc]FASTAAdd to Basket

« Hide

MQFSEELLTL KDQVRFDKSF KVGKYDKIVI AGMGGSGIAG RIFSEIYDEK    50
PVFLVDDYDI PSFVDDKTEF IAISYSGNTE ETISASEEAA KKHANVHAIT 100
SGGSLSKMGF DTIIIPSGLQ PRSSIGYLLM PLVNTFIKPK IGDVDEAYRL 150
LSETDKDNEE EKSIASEIYN GEHIPVIYGS RPFRAIAYRW KTQFNENAKV 200
LAYSNYFSEL NHNDTMPLKD TYRKDEFYFL VFRSDDSRFS KRITVTEKIT 250
GNSFRMVDVR GSSLLAKLFY LIHFGDYLTY HLAELRGVDP QDVSLIEKLK 300
KEIA 304
Length:304
Mass (Da):34,558
Last modified:October 1, 2001 - v1
Checksum:i09BD551B9A286EA6
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000011 Genomic DNA. Translation: BAB60606.1.
RefSeqiNP_111957.1. NC_002689.2.
WP_010917694.1. NC_002689.2.

Genome annotation databases

EnsemblBacteriaiBAB60606; BAB60606; BAB60606.
GeneIDi1442154.
KEGGitvo:TVN1438.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000011 Genomic DNA. Translation: BAB60606.1 .
RefSeqi NP_111957.1. NC_002689.2.
WP_010917694.1. NC_002689.2.

3D structure databases

ProteinModelPortali Q978F3.
ModBasei Search...

Protein-protein interaction databases

STRINGi 273116.TVN1438.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAB60606 ; BAB60606 ; BAB60606 .
GeneIDi 1442154.
KEGGi tvo:TVN1438.

Phylogenomic databases

eggNOGi COG0166.
KOi K15916.
OMAi IAERWKG.

Enzyme and pathway databases

BioCyci TVOL273116:GC31-1487-MONOMER.

Family and domain databases

InterProi IPR011857. Glu6P/Mann6P_isomerase.
IPR019490. Glu6P/Mann6P_isomerase_C.
IPR001347. SIS.
[Graphical view ]
Pfami PF10432. bact-PGI_C. 1 hit.
PF01380. SIS. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR02128. G6PI_arch. 1 hit.
PROSITEi PS51464. SIS. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1.

Entry informationi

Entry nameiPGMI_THEVO
AccessioniPrimary (citable) accession number: Q978F3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 21, 2006
Last sequence update: October 1, 2001
Last modified: September 3, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Multifunctional enzyme

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi