Endoglucanase A (Endo-1,4-beta-glucanase) (Cellulase A), secreted; dockerin domain

Preferred order of sections

Names and origin

Protein names

Submitted name:
Endoglucanase A (Endo-1,4-beta-glucanase) (Cellulase A), secreted; dockerin domain EMBL AAK78891.1

Gene names

Ordered Locus Names:

CA_C0915

Organism

Clostridium acetobutylicum

Taxonomic identifier

1488 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Clostridia › Clostridiales › Clostridiaceae › Clostridium

Protein attributes

Sequence length	606 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Ligand	Calcium PDB 3IK2 Metal-binding PDB 3IK2
Technical term	3D-structure PDB 3IK2 Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	polysaccharide catabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	hydrolase activity, hydrolyzing O-glycosyl compounds Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Sites

Metal binding

80

1

Calcium PDB 3IK2

Metal binding

176

1

Calcium; via carbonyl oxygen PDB 3IK2

Metal binding

179

1

Calcium PDB 3IK2

Metal binding

181

1

Calcium; via carbonyl oxygen PDB 3IK2

Sequences

Sequence

Length

Mass (Da)

Tools

Q977Y3 [UniParc].

Last modified October 1, 2001. Version 1.
Checksum: EC00E082846F4CDB
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FASTA

606

66,778

        10         20         30         40         50         60 
MKRNKILVSA LAIAFSSMVL TPVSGLKVFA DTADVNVNID TNAEKQAISP YIYGTNQDFS 

        70         80         90        100        110        120 
NAKVTARRIG GNRSTGYNWE NNDSNAGTDW KNESDNYWLT LYDVPKEKYN EPASVYTAFH 

       130        140        150        160        170        180 
DKSLAMGVPY SLVTLQAGGY VAADQSGPLA NTDVAPSSKW KKVEFNKNGP LSLTPDTTDG 

       190        200        210        220        230        240 
SVYMDEFVNY LVNKYGSASG SKGIKGYSLD NEPSLWPSTH PLIHPDKTKC SEVLDKDTQL 

       250        260        270        280        290        300 
AQVVKKIDPA AETFGPALFG FSAFNDFNSS PDWSSVKGNY QWFIDYYLDN MKKNSDAAGK 

       310        320        330        340        350        360 
RLLDALDLHW YPEAKGGGQR VTTSDTSNVD CNKARMQAPR SLWDSTYTED SWIGQWCKWG 

       370        380        390        400        410        420 
LPLIPKVKSS IDKYYPGTKL SFSEYNYGGE DHISGGIAQA DALGVFGKYG VYFATYWECN 

       430        440        450        460        470        480 
SDKNNYVQSA FNLYNNYDGN NSKYGDTDVK CDTSDINNSS TYASVTSNDG NKMDIIVMNK 

       490        500        510        520        530        540 
NYTDSINFNF NVSSNKNYTS GQVWGFDSNS SNITKRDDVS SISGNKFTYK IPALTAVHIV 

       550        560        570        580        590        600 
LTTAQKSSVK GDVNGDGVVN GRDLMELRKY LAGSTSNIDL NAADLNNDGA VNGRDLLELI 


KLVFEK

« Hide

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Genome sequence and comparative analysis of the solvent-producing bacterium Clostridium acetobutylicum." Noelling J., Breton G., Omelchenko M.V., Makarova K.S., Zeng Q., Gibson R., Lee H.M., Dubois J., Qiu D., Hitti J., Wolf Y.I., Tatusov R.L., Sabathe F., Doucette-Stamm L.A., Soucaille P., Daly M.J., Bennett G.N., Koonin E.V., Smith D.R. J. Bacteriol. 183:4823-4838(2001) [PubMed: 11466286] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787.
[2]	"Tertiary structure and characterization of a glycoside hydrolase family 44 endoglucanase from Clostridium acetobutylicum." Warner C.D., Hoy J.A., Shilling T.C., Linnen M.J., Ginder N.D., Ford C.F., Honzatko R.B., Reilly P.J. Appl. Environ. Microbiol. 76:338-346(2010) [PubMed: 19915043] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.20 ANGSTROMS) OF 34-541 IN COMPLEX WITH CALCIUM.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AE001437 Genomic DNA. Translation: AAK78891.1.

PIR

H97012.

RefSeq

NP_347551.1. NC_003030.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
3IK2	X-ray	2.20	A	34-541	[»]

ProteinModelPortal

Q977Y3.

SMR

Q977Y3. Positions 35-541.

ModBase

Search...

Protein family/group databases

CAZy

GH44. Glycoside Hydrolase Family 44.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

GeneID

1117098.

GenomeReviews

Gene locus CA_C0915 in contig AE001437_GR.

KEGG

cac:CA_C0915.

NMPDR

fig|272562.1.peg.1080.

PATRIC

32036209. VBICloAce74127_1124.

Phylogenomic databases

HOGENOM

HBG465396.

OMA

SSTHPRI.

ProtClustDB

CLSK2460753.

Family and domain databases

InterPro

IPR016134. Cellulos_enz_dockerin_1.
IPR018242. Dockerin_1.
IPR018247. EF_Hand_1_Ca_BS.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]

Gene3D

G3DSA:1.10.1330.10. Cellulos_enz_dockerin_1. 1 hit.

Pfam

PF00404. Dockerin_1. 2 hits.
[Graphical view]

SUPFAM

SSF63446. Cellulos_enz_dockerin_1. 1 hit.
SSF51445. Glyco_hydro_cat. 1 hit.

PROSITE

PS00018. EF_HAND_1. 2 hits.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

Q977Y3_CLOAB

Accession

Primary (citable) accession number: Q977Y3

Entry history

Integrated into UniProtKB/TrEMBL:	October 1, 2001
Last sequence update:	October 1, 2001
Last modified:	December 14, 2011
This is version 64 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)