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Q976M1

- SYW_SULTO

UniProt

Q976M1 - SYW_SULTO

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Protein

Tryptophan--tRNA ligase

Gene

trpS

Organism
Sulfolobus tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + L-tryptophyl-tRNA(Trp).UniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. tryptophan-tRNA ligase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. tryptophanyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciSTOK273063:GJC7-187-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Tryptophan--tRNA ligaseUniRule annotation (EC:6.1.1.2UniRule annotation)
Alternative name(s):
Tryptophanyl-tRNA synthetaseUniRule annotation
Short name:
TrpRSUniRule annotation
Gene namesi
Name:trpSUniRule annotation
Ordered Locus Names:STK_01690
OrganismiSulfolobus tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)
Taxonomic identifieri273063 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus
ProteomesiUP000001015: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 381381Tryptophan--tRNA ligasePRO_0000136734Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi273063.ST0169.

Structurei

3D structure databases

ProteinModelPortaliQ976M1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi82 – 909"HIGH" region
Motifi254 – 2585"KMSKS" region

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0180.
HOGENOMiHOG000224742.
KOiK01867.

Family and domain databases

Gene3Di3.40.50.620. 1 hit.
HAMAPiMF_00140_A. Trp_tRNA_synth_A.
InterProiIPR002305. aa-tRNA-synth_Ic.
IPR014729. Rossmann-like_a/b/a_fold.
IPR002306. Trp-tRNA-ligase.
IPR020653. Tryptophan-tRNA-ligase_arc.
[Graphical view]
PANTHERiPTHR10055. PTHR10055. 1 hit.
PfamiPF00579. tRNA-synt_1b. 1 hit.
[Graphical view]
PRINTSiPR01039. TRNASYNTHTRP.
TIGRFAMsiTIGR00233. trpS. 1 hit.

Sequencei

Sequence statusi: Complete.

Q976M1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAQDFNVTPW EVKGKVDYDK LIVQFGTQKI TSELKEKIKS IINDELHVML
60 70 80 90 100
RRDVFFSHRD LDLVLKDYQD GKGFFLYTGR APSLGMHIGH LIPFIFTKWL
110 120 130 140 150
QDKFNVNLYI EITDDEKFMR NPEYTLDQTR QWAYDNILDI IAVGFNPDKT
160 170 180 190 200
FIFQDTEYIR NMYPIAIKIA KKLTFSEVRA TFGLDTSSNI GIIWYPALQI
210 220 230 240 250
APTMFEKRRC LIPAGIDQDP YWRLQRDIAE SLGYYKAAQI HSKFLPPLTG
260 270 280 290 300
PEGKMSSSQP ETAIYLTDDP KTVERKIMKY AFSGGQPTIE LHRKYGGNPD
310 320 330 340 350
IDVSFQWLYM FFEPDDNKIK KIEEDYRSGA LLTGELKQIL IEKLNDFLEE
360 370 380
HRQKREEAKK LVNVFKYDGE LAREMWRKIH E
Length:381
Mass (Da):44,718
Last modified:April 16, 2002 - v2
Checksum:i109F5A56AF7D7159
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000023 Genomic DNA. Translation: BAK54171.1.
RefSeqiNP_376017.2. NC_003106.2.
WP_010978108.1. NC_003106.2.

Genome annotation databases

EnsemblBacteriaiBAK54171; BAK54171; STK_01690.
GeneIDi1458052.
KEGGisto:ST0169.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000023 Genomic DNA. Translation: BAK54171.1 .
RefSeqi NP_376017.2. NC_003106.2.
WP_010978108.1. NC_003106.2.

3D structure databases

ProteinModelPortali Q976M1.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 273063.ST0169.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAK54171 ; BAK54171 ; STK_01690 .
GeneIDi 1458052.
KEGGi sto:ST0169.

Phylogenomic databases

eggNOGi COG0180.
HOGENOMi HOG000224742.
KOi K01867.

Enzyme and pathway databases

BioCyci STOK273063:GJC7-187-MONOMER.

Family and domain databases

Gene3Di 3.40.50.620. 1 hit.
HAMAPi MF_00140_A. Trp_tRNA_synth_A.
InterProi IPR002305. aa-tRNA-synth_Ic.
IPR014729. Rossmann-like_a/b/a_fold.
IPR002306. Trp-tRNA-ligase.
IPR020653. Tryptophan-tRNA-ligase_arc.
[Graphical view ]
PANTHERi PTHR10055. PTHR10055. 1 hit.
Pfami PF00579. tRNA-synt_1b. 1 hit.
[Graphical view ]
PRINTSi PR01039. TRNASYNTHTRP.
TIGRFAMsi TIGR00233. trpS. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 16993 / JCM 10545 / NBRC 100140 / 7.

Entry informationi

Entry nameiSYW_SULTO
AccessioniPrimary (citable) accession number: Q976M1
Secondary accession number(s): F9VMM5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 16, 2002
Last sequence update: April 16, 2002
Last modified: October 29, 2014
This is version 72 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3