Q976I0 (PTH_SULTO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Peptidyl-tRNA hydrolase
Short name=PTH
EC=3.1.1.29

Gene names

Name:	pth
Ordered Locus Names:	STK_02080

Organism

Sulfolobus tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) [Complete proteome] [HAMAP]

Taxonomic identifier

273063 [NCBI]

Taxonomic lineage

Archaea › Crenarchaeota › Thermoprotei › Sulfolobales › Sulfolobaceae › Sulfolobus

Protein attributes

Sequence length	121 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis By similarity. HAMAP MF_00628
Catalytic activity	N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA. HAMAP MF_00628
Subcellular location	Cytoplasm By similarity HAMAP MF_00628.
Sequence similarities	Belongs to the PTH2 family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	aminoacyl-tRNA hydrolase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 121	121	Peptidyl-tRNA hydrolase HAMAP MF_00628		PRO_0000120305

Sequences

	Sequence		Length	Mass (Da)
	Q976I0 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: E8E370D6A036FC3B	FASTA	121	13,264
	10 20 30 40 50 60 MATKMVIVVR TDLDMGKGKI AAQVAHAAVS LVLDILNSSN SLWKEWLYKW LEEGQPKIVV 70 80 90 100 110 120 KVPSLDELNK RYEKAIELNL PTTIIQDAGK TQIEPGTITC IGIGPAPVEL VDKITGDLKL L

References

[1]

"Complete genome sequence of an aerobic thermoacidophilic Crenarchaeon, Sulfolobus tokodaii strain7." Kawarabayasi Y., Hino Y., Horikawa H., Jin-no K., Takahashi M., Sekine M., Baba S., Ankai A., Kosugi H., Hosoyama A., Fukui S., Nagai Y., Nishijima K., Otsuka R., Nakazawa H., Takamiya M., Kato Y., Yoshizawa T. , Tanaka T., Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K., Masuda S., Yanagii M., Nishimura M., Yamagishi A., Oshima T., Kikuchi H. DNA Res. 8:123-140(2001) [PubMed: 11572479] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 16993 / JCM 10545 / NBRC 100140 / 7.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000023 Genomic DNA. Translation: BAB65167.1.
RefSeq	NP_376058.1. NC_003106.2.
3D structure databases
ProteinModelPortal	Q976I0.
SMR	Q976I0. Positions 4-121.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1458097.
GenomeReviews	Gene locus ST0208 in contig BA000023_GR.
KEGG	sto:ST0208.
NMPDR	fig|273063.1.peg.226.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG526257.
OMA	KSLVMEY.
PhylomeDB	Q976I0.
ProtClustDB	PRK04322.
Enzyme and pathway databases
BioCyc	STOK273063:ST0208-MONOMER.
Family and domain databases
HAMAP	MF_00628. Pept_tRNA_hydro_arch. [Tree]
InterPro	IPR023476. Pep_tRNA_hydro_II_dom. IPR002833. Pep_tRNA_hydro_PTH2. [Graphical view]
Gene3D	G3DSA:3.40.1490.10. G3DSA:3.40.1490.10. 1 hit.
KO	K04794.
Pfam	PF01981. PTH2. 1 hit. [Graphical view]
SUPFAM	SSF102462. SSF102462. 1 hit.
TIGRFAMs	TIGR00283. Arch_pth2. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PTH_SULTO

Accession

Primary (citable) accession number: Q976I0

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 28, 2003
Last sequence update:	December 1, 2001
Last modified:	December 14, 2011
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program