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Protein

DNA-directed RNA polymerase subunit A''

Gene

rpoA2

Organism
Sulfolobus tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.By similarity

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

Transcription

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-directed RNA polymerase subunit A'' (EC:2.7.7.6)
Gene namesi
Name:rpoA2
Ordered Locus Names:STK_02750
OrganismiSulfolobus tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)
Taxonomic identifieri273063 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus
Proteomesi
  • UP000001015 Componenti: Chromosome

Subcellular locationi

Keywords - Cellular componenti

DNA-directed RNA polymerase

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000740271 – 392DNA-directed RNA polymerase subunit A''Add BLAST392

Interactioni

Subunit structurei

This RNA polymerase is composed of 13 subunits.By similarity

Protein-protein interaction databases

STRINGi273063.ST0275.

Structurei

3D structure databases

ProteinModelPortaliQ976A6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RNA polymerase beta' chain family.Curated

Phylogenomic databases

eggNOGiarCOG04256. Archaea.
COG0086. LUCA.
HOGENOMiHOG000222986.
KOiK03042.
OMAiRPIGRHG.

Family and domain databases

CDDicd06528. RNAP_A''. 1 hit.
HAMAPiMF_00411. RNApol_arch_A. 1 hit.
InterProiIPR007081. RNA_pol_Rpb1_5.
IPR012757. RNAP_A2.
[Graphical view]
PfamiPF04998. RNA_pol_Rpb1_5. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02389. RNA_pol_rpoA2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q976A6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVSDYIKSYI ERSLEQIRDK LPDKVIQDLR EALLNTDINL TESDVDKIID
60 70 80 90 100
LAVKDYQESL IEPGEAVGIV SAQSIGEPGT QMTLRTFHFA GIRELNVTLG
110 120 130 140 150
LPRLIEIVDA RKTPSTPIMT IYLTDEYKYD KEKALEIARK IEYTKIENVI
160 170 180 190 200
SSISVDITNM SITIQLDEEM LKDKGVDPSS VKKIISKLKL GKIRIEDIDD
210 220 230 240 250
YTFTIYFEEI DNISALFKMR EKLLNTKIKG IKGIRRAIVQ KKGDEYVIIT
260 270 280 290 300
DGSNLEGVIG IKGVDVNKIQ TNNIHEIADT FGIEAAREAI AREIKKVLEE
310 320 330 340 350
QGLDVDMRHI LLVADIMTRT GVVRQIGRHG VTGEKSSVLA RAAFEVTVKH
360 370 380 390
LLDAAARGEM EEFKGVVENI IIGQPIRLGT GIVELTMRLN VR
Length:392
Mass (Da):43,994
Last modified:May 15, 2002 - v2
Checksum:i4C6D4D7976D41B65
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000023 Genomic DNA. Translation: BAK54217.1.
RefSeqiWP_052846867.1. NC_003106.2.

Genome annotation databases

EnsemblBacteriaiBAK54217; BAK54217; STK_02750.
GeneIDi1458176.
KEGGisto:STK_02750.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000023 Genomic DNA. Translation: BAK54217.1.
RefSeqiWP_052846867.1. NC_003106.2.

3D structure databases

ProteinModelPortaliQ976A6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi273063.ST0275.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAK54217; BAK54217; STK_02750.
GeneIDi1458176.
KEGGisto:STK_02750.

Phylogenomic databases

eggNOGiarCOG04256. Archaea.
COG0086. LUCA.
HOGENOMiHOG000222986.
KOiK03042.
OMAiRPIGRHG.

Family and domain databases

CDDicd06528. RNAP_A''. 1 hit.
HAMAPiMF_00411. RNApol_arch_A. 1 hit.
InterProiIPR007081. RNA_pol_Rpb1_5.
IPR012757. RNAP_A2.
[Graphical view]
PfamiPF04998. RNA_pol_Rpb1_5. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02389. RNA_pol_rpoA2. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiRPOA2_SULTO
AccessioniPrimary (citable) accession number: Q976A6
Secondary accession number(s): F9VMS1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 15, 2002
Last sequence update: May 15, 2002
Last modified: October 5, 2016
This is version 75 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.