Q975P3 (APGM_SULTO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
2,3-bisphosphoglycerate-independent phosphoglycerate mutase
Short name=BPG-independent PGAM
Short name=Phosphoglyceromutase
Short name=aPGAM
EC=5.4.2.1

Gene names

Name:	apgM
Ordered Locus Names:	STK_03770

Organism

Sulfolobus tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) [Complete proteome] [HAMAP]

Taxonomic identifier

273063 [NCBI]

Taxonomic lineage

Archaea › Crenarchaeota › Thermoprotei › Sulfolobales › Sulfolobaceae › Sulfolobus

Protein attributes

Sequence length	413 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate By similarity. HAMAP MF_01402_A
Catalytic activity	2-phospho-D-glycerate = 3-phospho-D-glycerate. HAMAP MF_01402_A
Pathway	Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5. HAMAP MF_01402_A
Sequence similarities	Belongs to the BPG-independent phosphoglycerate mutase family. A-PGAM subfamily.

Ontologies

Keywords
Biological process	Glycolysis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	metal ion binding Inferred from electronic annotation. Source: InterPro phosphoglycerate mutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 413	413	2,3-bisphosphoglycerate-independent phosphoglycerate mutase HAMAP MF_01402_A		PRO_0000138149

Sequences

	Sequence		Length	Mass (Da)
	Q975P3 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: 5BB04C0FB48A11A5	FASTA	413	45,507
	10 20 30 40 50 60 MKQYKILFFI ADGLGDRPVR KLQGKTPLEY VDKPNIRELL KNSIIGLMDP ISPGVVAGSD 70 80 90 100 110 120 TSHLSMFGLD PHKYYRGRGA FEAIGAGARL KASDVAFRGN FATVNNEFIV VDRRAGRKIE 130 140 150 160 170 180 EADDLVKELN EKIGEIDGVK VRFYHGTEHR VAVVLSGKGL TDKVSDTDPH EVNKKVLESK 190 200 210 220 230 240 PLDNSPESQF TANIINKLTR KIYEILNSSE INKIRVSKGE LPANIILLRG AAEFVELPQF 250 260 270 280 290 300 ESYTKLKAAA VSATALIKGI CEQIGMRVVT PPGATGGLDT NYLGKADAAV ELLKEYDFVF 310 320 330 340 350 360 LHLKATDAAS HDGNVDGKVY AINKMDEMIG RILDKLGSEL VIAISGDHTT PVEVKEHTGD 370 380 390 400 410 PVPFLLYVPY DIINDVVNDF NEREARRGSL RIRGLDVINL LLNYSNRAEK YGA

References

[1]

"Complete genome sequence of an aerobic thermoacidophilic Crenarchaeon, Sulfolobus tokodaii strain7." Kawarabayasi Y., Hino Y., Horikawa H., Jin-no K., Takahashi M., Sekine M., Baba S., Ankai A., Kosugi H., Hosoyama A., Fukui S., Nagai Y., Nishijima K., Otsuka R., Nakazawa H., Takamiya M., Kato Y., Yoshizawa T. , Tanaka T., Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K., Masuda S., Yanagii M., Nishimura M., Yamagishi A., Oshima T., Kikuchi H. DNA Res. 8:123-140(2001) [PubMed: 11572479] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: DSM 16993 / JCM 10545 / NBRC 100140 / 7.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000023 Genomic DNA. Translation: BAB65357.1.
RefSeq	NP_376248.1. NC_003106.2.
3D structure databases
ProteinModelPortal	Q975P3.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1458301.
GenomeReviews	Gene locus ST0377 in contig BA000023_GR.
KEGG	sto:ST0377.
NMPDR	fig|273063.1.peg.416.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG463247.
OMA	DIAFRCN.
ProtClustDB	PRK04024.
Enzyme and pathway databases
BioCyc	STOK273063:ST0377-MONOMER.
Family and domain databases
HAMAP	MF_01402_A. ApgM_A. [Tree]
InterPro	IPR017849. Alkaline_Pase-like_a/b/a. IPR017850. Alkaline_phosphatase_core. IPR023665. ApgAM. IPR004456. BisP-indep_Pglycerate_Mutase. IPR006124. Metalloenzyme. [Graphical view]
Gene3D	G3DSA:3.40.720.10. Alk_phosphtse. 2 hits.
KO	K15635.
Pfam	PF01676. Metalloenzyme. 1 hit. PF10143. PhosphMutase. 1 hit. [Graphical view]
PIRSF	PIRSF006392. IPGAM_arch. 1 hit.
SUPFAM	SSF53649. Alkaline_phosphatase_core. 1 hit.
TIGRFAMs	TIGR00306. ApgM. 1 hit.
ProtoNet	Search...

Entry information

Entry name

APGM_SULTO

Accession

Primary (citable) accession number: Q975P3

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 2, 2002
Last sequence update:	December 1, 2001
Last modified:	January 25, 2012
This is version 59 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program