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Protein

Probable cyclic pyranopterin monophosphate synthase accessory protein

Gene

moaC

Organism
Sulfolobus tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Together with MoaA, is involved in the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z).UniRule annotation

Pathwayi: molybdopterin biosynthesis

This protein is involved in the pathway molybdopterin biosynthesis, which is part of Cofactor biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway molybdopterin biosynthesis and in Cofactor biosynthesis.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei117 – 1171UniRule annotation

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Molybdenum cofactor biosynthesis

Enzyme and pathway databases

BioCyciSTOK273063:GJC7-551-MONOMER.
BRENDAi4.1.99.18. 6166.
UniPathwayiUPA00344.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable cyclic pyranopterin monophosphate synthase accessory proteinUniRule annotation
Alternative name(s):
Molybdenum cofactor biosynthesis protein CUniRule annotation
Gene namesi
Name:moaCUniRule annotation
Ordered Locus Names:STK_04720
OrganismiSulfolobus tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)
Taxonomic identifieri273063 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus
Proteomesi
  • UP000001015 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 151151Probable cyclic pyranopterin monophosphate synthase accessory proteinPRO_0000097865Add
BLAST

Interactioni

Subunit structurei

Homohexamer; trimer of dimers.1 Publication

Protein-protein interaction databases

STRINGi273063.ST0472.

Structurei

Secondary structure

1
151
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi15 – 2612Combined sources
Helixi29 – 368Combined sources
Helixi45 – 6319Combined sources
Beta strandi74 – 829Combined sources
Beta strandi85 – 9814Combined sources
Helixi101 – 11818Combined sources
Helixi120 – 1234Combined sources
Beta strandi134 – 14310Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2OHDX-ray2.20A/B/C/D/E/F1-151[»]
ProteinModelPortaliQ975D5.
SMRiQ975D5. Positions 4-147.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ975D5.

Family & Domainsi

Sequence similaritiesi

Belongs to the MoaC family.UniRule annotation

Phylogenomic databases

eggNOGiarCOG01530. Archaea.
COG0315. LUCA.
HOGENOMiHOG000228417.
KOiK03637.
OMAiCEVRAYY.

Family and domain databases

Gene3Di3.30.70.640. 1 hit.
HAMAPiMF_01224_A. MoaC_A.
InterProiIPR023045. Mo_CF_biosynth-C.
IPR023047. Mo_CF_biosynth-C_arc.
IPR002820. Mopterin_CF_biosynth-C_dom.
[Graphical view]
PfamiPF01967. MoaC. 1 hit.
[Graphical view]
SUPFAMiSSF55040. SSF55040. 1 hit.
TIGRFAMsiTIGR00581. moaC. 1 hit.

Sequencei

Sequence statusi: Complete.

Q975D5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTEAKIVDIS SKDIVLREAV VEGYIKLRKE TIEKIKNKEV EKGDVITVAK
60 70 80 90 100
TAGILAAKKT PELIPMCHPI PLEFVDVEIK IEEEGLRVIS TVKAHYKTGV
110 120 130 140 150
EMEALTATSV ALLTIWDMVK KYEKDENGQY PYTEIKSIRV INKIKTYDDM

K
Length:151
Mass (Da):17,125
Last modified:December 1, 2001 - v1
Checksum:iA475C519B6ADDE27
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000023 Genomic DNA. Translation: BAB65466.1.
RefSeqiWP_010978449.1. NC_003106.2.

Genome annotation databases

EnsemblBacteriaiBAB65466; BAB65466; STK_04720.
GeneIDi1458415.
KEGGisto:STK_04720.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000023 Genomic DNA. Translation: BAB65466.1.
RefSeqiWP_010978449.1. NC_003106.2.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2OHDX-ray2.20A/B/C/D/E/F1-151[»]
ProteinModelPortaliQ975D5.
SMRiQ975D5. Positions 4-147.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi273063.ST0472.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAB65466; BAB65466; STK_04720.
GeneIDi1458415.
KEGGisto:STK_04720.

Phylogenomic databases

eggNOGiarCOG01530. Archaea.
COG0315. LUCA.
HOGENOMiHOG000228417.
KOiK03637.
OMAiCEVRAYY.

Enzyme and pathway databases

UniPathwayiUPA00344.
BioCyciSTOK273063:GJC7-551-MONOMER.
BRENDAi4.1.99.18. 6166.

Miscellaneous databases

EvolutionaryTraceiQ975D5.

Family and domain databases

Gene3Di3.30.70.640. 1 hit.
HAMAPiMF_01224_A. MoaC_A.
InterProiIPR023045. Mo_CF_biosynth-C.
IPR023047. Mo_CF_biosynth-C_arc.
IPR002820. Mopterin_CF_biosynth-C_dom.
[Graphical view]
PfamiPF01967. MoaC. 1 hit.
[Graphical view]
SUPFAMiSSF55040. SSF55040. 1 hit.
TIGRFAMsiTIGR00581. moaC. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 16993 / JCM 10545 / NBRC 100140 / 7.
  2. "Structure of a putative molybdenum-cofactor biosynthesis protein C (MoaC) from Sulfolobus tokodaii (ST0472)."
    Yoshida H., Yamada M., Kuramitsu S., Kamitori S.
    Acta Crystallogr. F 64:589-592(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.2 ANGSTROMS), SUBUNIT.

Entry informationi

Entry nameiMOAC_SULTO
AccessioniPrimary (citable) accession number: Q975D5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 19, 2002
Last sequence update: December 1, 2001
Last modified: December 9, 2015
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.