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Q973G0

- IF2A_SULTO

UniProt

Q973G0 - IF2A_SULTO

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Protein
Translation initiation factor 2 subunit alpha
Gene
eif2a, STK_09410
Organism
Sulfolobus tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA By similarity.UniRule annotation

GO - Molecular functioni

  1. translation initiation factor activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Initiation factor

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

RNA-binding

Enzyme and pathway databases

BioCyciSTOK273063:GJC7-1041-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Translation initiation factor 2 subunit alpha
Alternative name(s):
aIF2-alpha
eIF-2-alpha
Gene namesi
Name:eif2a
Ordered Locus Names:STK_09410
OrganismiSulfolobus tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)
Taxonomic identifieri273063 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus
ProteomesiUP000001015: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. eukaryotic translation initiation factor 2 complex Source: InterPro
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 263263Translation initiation factor 2 subunit alphaUniRule annotation
PRO_0000137403Add
BLAST

Interactioni

Subunit structurei

Heterotrimer composed of an alpha, a beta and a gamma chain By similarity.

Protein-protein interaction databases

STRINGi273063.ST0941.

Structurei

3D structure databases

ProteinModelPortaliQ973G0.
SMRiQ973G0. Positions 1-261.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini12 – 8372S1 motif
Add
BLAST

Sequence similaritiesi

Belongs to the eIF-2-alpha family.
Contains 1 S1 motif domain.

Phylogenomic databases

eggNOGiCOG1093.
HOGENOMiHOG000224965.
KOiK03237.
OMAiIDAEFEI.

Family and domain databases

Gene3Di1.10.150.190. 1 hit.
2.40.50.140. 1 hit.
3.30.70.1130. 1 hit.
HAMAPiMF_00231. eIF_2_alpha.
InterProiIPR012340. NA-bd_OB-fold.
IPR003029. Rbsml_prot_S1_RNA-bd_dom.
IPR022967. RNA-binding_domain_S1.
IPR022964. TIF2_asu_arc.
IPR024055. TIF2_asu_C.
IPR024054. TIF2_asu_middle.
IPR011488. TIF_2_asu.
[Graphical view]
PfamiPF07541. EIF_2_alpha. 1 hit.
PF00575. S1. 1 hit.
[Graphical view]
SMARTiSM00316. S1. 1 hit.
[Graphical view]
SUPFAMiSSF110993. SSF110993. 1 hit.
SSF116742. SSF116742. 1 hit.
SSF50249. SSF50249. 1 hit.
PROSITEiPS50126. S1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q973G0-1 [UniParc]FASTAAdd to Basket

« Hide

MIYNKNPIPT EGEILIATVK QIFDYGSYVT LDEYGNLQAF LPWSEISSRW    50
VKNIRDVIKE GRKIVVKVIR VDKRKGTIDV SLKKVTEDEK RKKMSQWKKI 100
QKVDKILEIV SQKINKTEKE GWEQVAWKLE DKYGDAYDAL VKAVKEGDSI 150
LKNAGVPEVW IKPLMEEIGK HIEEKRVKKS EIVTLRSSDP AGIEKIRKVL 200
GAAVEIAENA DVDIKIYTIG APRYRIDIIG TDPKLLSKVM TEILDNIREI 250
SKEEKVEFNV VRK 263
Length:263
Mass (Da):30,222
Last modified:December 1, 2001 - v1
Checksum:iACF12013C64C6497
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000023 Genomic DNA. Translation: BAB65953.1.
RefSeqiNP_376844.1. NC_003106.2.

Genome annotation databases

EnsemblBacteriaiBAB65953; BAB65953; STK_09410.
GeneIDi1458904.
KEGGisto:ST0941.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000023 Genomic DNA. Translation: BAB65953.1 .
RefSeqi NP_376844.1. NC_003106.2.

3D structure databases

ProteinModelPortali Q973G0.
SMRi Q973G0. Positions 1-261.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 273063.ST0941.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAB65953 ; BAB65953 ; STK_09410 .
GeneIDi 1458904.
KEGGi sto:ST0941.

Phylogenomic databases

eggNOGi COG1093.
HOGENOMi HOG000224965.
KOi K03237.
OMAi IDAEFEI.

Enzyme and pathway databases

BioCyci STOK273063:GJC7-1041-MONOMER.

Family and domain databases

Gene3Di 1.10.150.190. 1 hit.
2.40.50.140. 1 hit.
3.30.70.1130. 1 hit.
HAMAPi MF_00231. eIF_2_alpha.
InterProi IPR012340. NA-bd_OB-fold.
IPR003029. Rbsml_prot_S1_RNA-bd_dom.
IPR022967. RNA-binding_domain_S1.
IPR022964. TIF2_asu_arc.
IPR024055. TIF2_asu_C.
IPR024054. TIF2_asu_middle.
IPR011488. TIF_2_asu.
[Graphical view ]
Pfami PF07541. EIF_2_alpha. 1 hit.
PF00575. S1. 1 hit.
[Graphical view ]
SMARTi SM00316. S1. 1 hit.
[Graphical view ]
SUPFAMi SSF110993. SSF110993. 1 hit.
SSF116742. SSF116742. 1 hit.
SSF50249. SSF50249. 1 hit.
PROSITEi PS50126. S1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 16993 / JCM 10545 / NBRC 100140 / 7.

Entry informationi

Entry nameiIF2A_SULTO
AccessioniPrimary (citable) accession number: Q973G0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 10, 2002
Last sequence update: December 1, 2001
Last modified: May 14, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Translation initiation factors
    List of translation initiation factor entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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