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Q972I2 (CP119_SULTO) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Cytochrome P450 119
EC=1.14.-.-
Gene names
Name:cyp119
Ordered Locus Names:STK_11480
OrganismSulfolobus tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) [Complete proteome] [HAMAP]
Taxonomic identifier273063 [NCBI]
Taxonomic lineageArchaea › Crenarchaeota › Thermoprotei › Sulfolobales › Sulfolobaceae › Sulfolobus

Protein attributes

Sequence length367 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Cofactor

Binds 1 heme group per subunit.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the cytochrome P450 family.

Biophysicochemical properties

Temperature dependence:

Active up to 80 degrees Celsius. Thermostable.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 367367Cytochrome P450 119
PRO_0000343614

Sites

Metal binding3171Iron (heme axial ligand)
Binding site761Heme By similarity
Binding site801Heme
Binding site2571Heme By similarity
Binding site2591Heme
Binding site3151Heme

Secondary structure

1 ............................................................... 367
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q972I2 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: E001CB1FF8BA8E8C

FASTA36742,324
        10         20         30         40         50         60 
MYDWFKQMRK ESPVYYDGKV WNLFKYEDCK MVLNDHKRFS SNLTGYNDKL EMLRSGKVFF 

        70         80         90        100        110        120 
DIPTRYTMLT SDPPLHDELR NLTADAFNPS NLPVDFVREV TVKLLSELDE EFDVIESFAI 

       130        140        150        160        170        180 
PLPILVISKM LGINPDVKKV KDWSDLVALR LGRADEIFSI GRKYLELISF SKKELDSRKG 

       190        200        210        220        230        240 
KEIVDLTGKI ANSNLSELEK EGYFILLMIA GNETTTNLIG NAIEDFTLYN SWDYVREKGA 

       250        260        270        280        290        300 
LKAVEEALRF SPPVMRTIRV TKEKVKIRDQ VIDEGELVRV WIASANRDEE VFKDPDSFIP 

       310        320        330        340        350        360 
DRTPNPHLSF GSGIHLCLGA PLARLEARIA LEEFAKKFRV KEIVKKEKID NEVLNGYRKL 


VVRVERA

« Hide

References

« Hide 'large scale' references
[1]"Complete genome sequence of an aerobic thermoacidophilic Crenarchaeon, Sulfolobus tokodaii strain7."
Kawarabayasi Y., Hino Y., Horikawa H., Jin-no K., Takahashi M., Sekine M., Baba S., Ankai A., Kosugi H., Hosoyama A., Fukui S., Nagai Y., Nishijima K., Otsuka R., Nakazawa H., Takamiya M., Kato Y., Yoshizawa T. expand/collapse author list , Tanaka T., Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K., Masuda S., Yanagii M., Nishimura M., Yamagishi A., Oshima T., Kikuchi H.
DNA Res. 8:123-140(2001) [PubMed: 11572479] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: DSM 16993 / JCM 10545 / NBRC 100140 / 7.
[2]"Structure and direct electrochemistry of cytochrome P450 from the thermoacidophilic crenarchaeon, Sulfolobus tokodaii strain 7."
Oku Y., Ohtaki A., Kamitori S., Nakamura N., Yohda M., Ohno H., Kawarabayasi Y.
J. Inorg. Biochem. 98:1194-1199(2004) [PubMed: 15219985] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) IN COMPLEX WITH HEME, TEMPERATURE DEPENDENCE.
Strain: DSM 16993 / JCM 10545 / NBRC 100140 / 7.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BA000023 Genomic DNA. Translation: BAK54472.1.
RefSeqNP_377075.1. NC_003106.2.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1UE8X-ray3.00A1-366[»]
3B4XX-ray1.94A1-366[»]
ProteinModelPortalQ972I2.
SMRQ972I2. Positions 1-366.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1459138.
GenomeReviewsGene locus ST1148 in contig BA000023_GR.
KEGGsto:ST1148.
NMPDRfig|273063.1.peg.1243.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG695262.
OMAPPLHDEL.
ProtClustDBCLSK268599.

Enzyme and pathway databases

BioCycSTOK273063:ST1148-MONOMER.

Family and domain databases

InterProIPR001128. Cyt_P450.
IPR002397. Cyt_P450_B.
IPR017972. Cyt_P450_CS.
[Graphical view]
Gene3DG3DSA:1.10.630.10. Cyt_P450. 1 hit.
KOK00517.
PfamPF00067. p450. 1 hit.
[Graphical view]
PRINTSPR00359. BP450.
PR00385. P450.
SUPFAMSSF48264. Cytochrome_P450. 1 hit.
PROSITEPS00086. CYTOCHROME_P450. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCP119_SULTO
AccessionPrimary (citable) accession number: Q972I2
Secondary accession number(s): F9VNW4
Entry history
Integrated into UniProtKB/Swiss-Prot: July 22, 2008
Last sequence update: December 1, 2001
Last modified: January 25, 2012
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

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