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Q971X1 (SYR_SULTO) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:STK_12580
OrganismSulfolobus tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) [Complete proteome] [HAMAP]
Taxonomic identifier273063 [NCBI]
Taxonomic lineageArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus

Protein attributes

Sequence length623 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 623623Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_0000151657

Regions

Motif116 – 12611"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q971X1 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: A24645D0996B038B

FASTA62371,693
        10         20         30         40         50         60 
MNPIKEVKLE FAKILSERLS IDQNKIYENF EYPPKEQMGD VSLPLPTVTK NKELLNISDF 

        70         80         90        100        110        120 
PSGGKLIREI KKAGIYINGV INESELFKLI FTNFPEDYGI EKIQKPQRVV VEHTSANPIH 

       130        140        150        160        170        180 
PLHVGHLRNA ILGDVIARML KARGHEVNTR FYVNDAGRQV AILTLGYLLL GEPNPPRDEK 

       190        200        210        220        230        240 
IDQWIGVIYA ITNILIEINQ LKKELSSSNE EEYRQKISKL DELISLAGKH REKYPEIFDK 

       250        260        270        280        290        300 
LADEISKIEN IEEKIQNIIK NYERHSDEKI VNVIRKLVNW TLEGFKDSLK ILDIHFDNFD 

       310        320        330        340        350        360 
YESDLLWSKR VDEIVKLALS SKNIKEHKGT IALSLDLDPE ARKRLNIPLG LELPPLVLVR 

       370        380        390        400        410        420 
SDGTTLYTTR DIAYSLYKFE VFYANKVINV IAEQQSVPQM QLRASLYLLG FKDIAENLIH 

       430        440        450        460        470        480 
YSYGMVNLQG MRMSGRLGRY ISLDEIINEV KEVAENKIKE KGGDLNNLLD IVNSAIRYAI 

       490        500        510        520        530        540 
LSVSANKPVS FNIKNIVDFD QNSGPYLQYT YARAYNILAK NEEKLDINKV DFSDIVDDKR 

       550        560        570        580        590        600 
RLLISIAKFP EVATKAVDEL RPEDLLGFMR SIADIFNRWY NFERVLQEPN EGKRMLRLFI 

       610        620 
VKGVERILYN GLSIVGIKPL KRM 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000023 Genomic DNA. Translation: BAK54498.1.
RefSeqNP_377190.1. NC_003106.2.

3D structure databases

ProteinModelPortalQ971X1.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING273063.ST1258.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAK54498; BAK54498; STK_12580.
GeneID1459256.
KEGGsto:ST1258.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247213.
KOK01887.
OMADGTAVYM.
ProtClustDBPRK01611.

Enzyme and pathway databases

BioCycSTOK273063:GJC7-1392-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 2 hits.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 2 hits.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
ProtoNetSearch...

Entry information

Entry nameSYR_SULTO
AccessionPrimary (citable) accession number: Q971X1
Secondary accession number(s): F9VNZ0
Entry history
Integrated into UniProtKB/Swiss-Prot: October 10, 2002
Last sequence update: December 1, 2001
Last modified: April 16, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries