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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Sulfolobus tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligase (EC:6.1.1.19)
Alternative name(s):
Arginyl-tRNA synthetase
Short name:
ArgRS
Gene namesi
Name:argS
Ordered Locus Names:STK_12580
OrganismiSulfolobus tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)
Taxonomic identifieri273063 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus
Proteomesi
  • UP000001015 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001516571 – 623Arginine--tRNA ligaseAdd BLAST623

Interactioni

Protein-protein interaction databases

STRINGi273063.ST1258.

Structurei

3D structure databases

ProteinModelPortaliQ971X1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi116 – 126"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.

Phylogenomic databases

eggNOGiarCOG00487. Archaea.
COG0018. LUCA.
HOGENOMiHOG000247213.
KOiK01887.
OMAiNKPLHLG.
OrthoDBiPOG093Z013U.

Family and domain databases

CDDicd00671. ArgRS_core. 1 hit.
Gene3Di3.30.1360.70. 1 hit.
3.40.50.620. 2 hits.
HAMAPiMF_00123. Arg_tRNA_synth. 1 hit.
InterProiView protein in InterPro
IPR001278. Arg-tRNA-ligase.
IPR036695. Arg-tRNA-synth_N_sf.
IPR035684. ArgRS_core.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_Ia_anticodon-bd.
PANTHERiPTHR11956. PTHR11956. 1 hit.
PfamiView protein in Pfam
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
PRINTSiPR01038. TRNASYNTHARG.
SMARTiView protein in SMART
SM00836. DALR_1. 1 hit.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsiTIGR00456. argS. 1 hit.

Sequencei

Sequence statusi: Complete.

Q971X1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNPIKEVKLE FAKILSERLS IDQNKIYENF EYPPKEQMGD VSLPLPTVTK
60 70 80 90 100
NKELLNISDF PSGGKLIREI KKAGIYINGV INESELFKLI FTNFPEDYGI
110 120 130 140 150
EKIQKPQRVV VEHTSANPIH PLHVGHLRNA ILGDVIARML KARGHEVNTR
160 170 180 190 200
FYVNDAGRQV AILTLGYLLL GEPNPPRDEK IDQWIGVIYA ITNILIEINQ
210 220 230 240 250
LKKELSSSNE EEYRQKISKL DELISLAGKH REKYPEIFDK LADEISKIEN
260 270 280 290 300
IEEKIQNIIK NYERHSDEKI VNVIRKLVNW TLEGFKDSLK ILDIHFDNFD
310 320 330 340 350
YESDLLWSKR VDEIVKLALS SKNIKEHKGT IALSLDLDPE ARKRLNIPLG
360 370 380 390 400
LELPPLVLVR SDGTTLYTTR DIAYSLYKFE VFYANKVINV IAEQQSVPQM
410 420 430 440 450
QLRASLYLLG FKDIAENLIH YSYGMVNLQG MRMSGRLGRY ISLDEIINEV
460 470 480 490 500
KEVAENKIKE KGGDLNNLLD IVNSAIRYAI LSVSANKPVS FNIKNIVDFD
510 520 530 540 550
QNSGPYLQYT YARAYNILAK NEEKLDINKV DFSDIVDDKR RLLISIAKFP
560 570 580 590 600
EVATKAVDEL RPEDLLGFMR SIADIFNRWY NFERVLQEPN EGKRMLRLFI
610 620
VKGVERILYN GLSIVGIKPL KRM
Length:623
Mass (Da):71,693
Last modified:December 1, 2001 - v1
Checksum:iA24645D0996B038B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000023 Genomic DNA. Translation: BAK54498.1.
RefSeqiWP_010979277.1. NC_003106.2.

Genome annotation databases

EnsemblBacteriaiBAK54498; BAK54498; STK_12580.
GeneIDi1459256.
KEGGisto:STK_12580.
PATRICifig|273063.9.peg.1416.

Similar proteinsi

Entry informationi

Entry nameiSYR_SULTO
AccessioniPrimary (citable) accession number: Q971X1
Secondary accession number(s): F9VNZ0
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 10, 2002
Last sequence update: December 1, 2001
Last modified: November 22, 2017
This is version 95 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families