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Q971U9 (RIFK_SULTO) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Riboflavin kinase

Short name=RFK
EC=2.7.1.161
Alternative name(s):
CTP-dependent riboflavin kinase
CTP:riboflavin 5'-phosphotransferase
Flavokinase
Gene names
Name:ribK
Ordered Locus Names:STK_12800
OrganismSulfolobus tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) [Complete proteome] [HAMAP]
Taxonomic identifier273063 [NCBI]
Taxonomic lineageArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus

Protein attributes

Sequence length136 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) By similarity. HAMAP-Rule MF_01285

Catalytic activity

CTP + riboflavin = CDP + FMN. HAMAP-Rule MF_01285

Cofactor

Binds 1 magnesium ion per subunit By similarity. HAMAP-Rule MF_01285

Pathway

Cofactor biosynthesis; FMN biosynthesis; FMN from riboflavin (CTP route): step 1/1. HAMAP-Rule MF_01285

Sequence similarities

Belongs to the archaeal riboflavin kinase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 136136Riboflavin kinase HAMAP-Rule MF_01285
PRO_0000322080

Regions

Nucleotide binding15 – 206CDP By similarity
Nucleotide binding116 – 1194CDP By similarity

Sites

Metal binding441Magnesium By similarity
Metal binding461Magnesium By similarity
Binding site1031FMN By similarity
Binding site1111FMN By similarity

Sequences

Sequence LengthMass (Da)Tools
Q971U9 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: 0FFCB18C7770D092

FASTA13615,284
        10         20         30         40         50         60 
MRTKILHIKG KVTAGLGEGR IFLSIPYYIE SFKKYLGFEP YAGTLNIVIY DRISLENRLI 

        70         80         90        100        110        120 
LDLAKGIIIP EHKEPNRVLG SVKAFPSSIN SISPAAIVIP ARTTHPKSVI EIISPYYLRE 

       130 
KLSLKDGDEV EIEVYL 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000023 Genomic DNA. Translation: BAB66321.1.
RefSeqNP_377212.1. NC_003106.2.

3D structure databases

ProteinModelPortalQ971U9.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING273063.ST1280.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAB66321; BAB66321; STK_12800.
GeneID1459279.
KEGGsto:ST1280.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1339.
HOGENOMHOG000015512.
KOK07732.
OMAPYEGTLN.
ProtClustDBCLSK802937.

Enzyme and pathway databases

BioCycSTOK273063:GJC7-1415-MONOMER.
UniPathwayUPA00276; UER00929.

Family and domain databases

Gene3D2.40.30.30. 1 hit.
HAMAPMF_01285. Riboflavin_kinase.
InterProIPR023470. Riboflavin_kinase_archaeal.
IPR015865. Riboflavin_kinase_bac/euk.
IPR023602. Riboflavin_kinase_CTP-dep.
IPR023465. Riboflavin_kinase_domain.
[Graphical view]
PfamPF01982. CTP-dep_RFKase. 1 hit.
[Graphical view]
SUPFAMSSF82114. SSF82114. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRIFK_SULTO
AccessionPrimary (citable) accession number: Q971U9
Entry history
Integrated into UniProtKB/Swiss-Prot: February 26, 2008
Last sequence update: December 1, 2001
Last modified: February 19, 2014
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways