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Q970V0

- ASSY_SULTO

UniProt

Q970V0 - ASSY_SULTO

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Protein

Argininosuccinate synthase

Gene
argG, STK_15010
Organism
Sulfolobus tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-citrulline + L-aspartate = AMP + diphosphate + N(omega)-(L-arginino)succinate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei84 – 841Citrulline By similarity
Binding sitei114 – 1141ATP; via amide nitrogen By similarity
Binding sitei116 – 1161Aspartate By similarity
Binding sitei120 – 1201Aspartate By similarity
Binding sitei120 – 1201Citrulline By similarity
Binding sitei121 – 1211Aspartate By similarity
Binding sitei124 – 1241Citrulline By similarity
Binding sitei171 – 1711Citrulline By similarity
Binding sitei180 – 1801Citrulline By similarity
Binding sitei253 – 2531Citrulline By similarity
Binding sitei265 – 2651Citrulline By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi6 – 149ATP By similarity

GO - Molecular functioni

  1. argininosuccinate synthase activity Source: UniProtKB-HAMAP
  2. ATP binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. arginine biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Amino-acid biosynthesis, Arginine biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciSTOK273063:GJC7-1673-MONOMER.
UniPathwayiUPA00068; UER00113.

Names & Taxonomyi

Protein namesi
Recommended name:
Argininosuccinate synthase (EC:6.3.4.5)
Alternative name(s):
Citrulline--aspartate ligase
Gene namesi
Name:argG
Ordered Locus Names:STK_15010
OrganismiSulfolobus tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)
Taxonomic identifieri273063 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus
ProteomesiUP000001015: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 390390Argininosuccinate synthaseUniRule annotationPRO_0000148687Add
BLAST

Interactioni

Subunit structurei

Homotetramer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi273063.ST1501.

Structurei

3D structure databases

ProteinModelPortaliQ970V0.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0137.
HOGENOMiHOG000230093.
KOiK01940.
OMAiAPPEEAY.

Family and domain databases

Gene3Di3.40.50.620. 1 hit.
3.90.1260.10. 1 hit.
HAMAPiMF_00005. Arg_succ_synth_type1.
InterProiIPR001518. Arginosuc_synth.
IPR018223. Arginosuc_synth_CS.
IPR023434. Arginosuc_synth_type_1_subfam.
IPR024074. AS_cat/multimer_dom_body.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PfamiPF00764. Arginosuc_synth. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00032. argG. 1 hit.
PROSITEiPS00564. ARGININOSUCCIN_SYN_1. 1 hit.
PS00565. ARGININOSUCCIN_SYN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q970V0-1 [UniParc]FASTAAdd to Basket

« Hide

MKIVLAYSGG LDTTVAIRWL KETFNADVIT VTVDVGQKDN FEDIEKRAYI    50
AGATKHYTID AKKEFADNFI SYAIKMNALY EDVYPLSTAL ARPLIAQKVV 100
EIAKKEKVDY IAHGSTSKGN DQVRFDLAVK ALYPEAKIIA PARIWNMTRE 150
KEIEFAKARG IPIKTESSKY SIDENLWGRS IEGDDISDPS KEVPEDAFEW 200
TKKKNNGKIT LSIEFEKGIP VAINNEKMDL VKIIQVLNEV VGSYGFGRVE 250
HLENRVVGFK SREVYEVPAA LVLINSHKDL EKTVYSPLEF RFKKYIDSQW 300
ADLVYQGLWF EPLRETIQLA GDNLNKWVTG EVKIEIEGNG MRTLGRASKY 350
SPFSEKVASY NKGWYPTDEM ARGFIEIYGM HSLLTRQVRE 390
Length:390
Mass (Da):44,392
Last modified:December 1, 2001 - v1
Checksum:iF7BE769E0D29E2B6
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000023 Genomic DNA. Translation: BAK54606.1.
RefSeqiNP_377464.1. NC_003106.2.

Genome annotation databases

EnsemblBacteriaiBAK54606; BAK54606; STK_15010.
GeneIDi1459537.
KEGGisto:ST1501.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BA000023 Genomic DNA. Translation: BAK54606.1 .
RefSeqi NP_377464.1. NC_003106.2.

3D structure databases

ProteinModelPortali Q970V0.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 273063.ST1501.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAK54606 ; BAK54606 ; STK_15010 .
GeneIDi 1459537.
KEGGi sto:ST1501.

Phylogenomic databases

eggNOGi COG0137.
HOGENOMi HOG000230093.
KOi K01940.
OMAi APPEEAY.

Enzyme and pathway databases

UniPathwayi UPA00068 ; UER00113 .
BioCyci STOK273063:GJC7-1673-MONOMER.

Family and domain databases

Gene3Di 3.40.50.620. 1 hit.
3.90.1260.10. 1 hit.
HAMAPi MF_00005. Arg_succ_synth_type1.
InterProi IPR001518. Arginosuc_synth.
IPR018223. Arginosuc_synth_CS.
IPR023434. Arginosuc_synth_type_1_subfam.
IPR024074. AS_cat/multimer_dom_body.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view ]
Pfami PF00764. Arginosuc_synth. 1 hit.
[Graphical view ]
TIGRFAMsi TIGR00032. argG. 1 hit.
PROSITEi PS00564. ARGININOSUCCIN_SYN_1. 1 hit.
PS00565. ARGININOSUCCIN_SYN_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 16993 / JCM 10545 / NBRC 100140 / 7.

Entry informationi

Entry nameiASSY_SULTO
AccessioniPrimary (citable) accession number: Q970V0
Secondary accession number(s): F9VNG0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 23, 2003
Last sequence update: December 1, 2001
Last modified: May 14, 2014
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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