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Protein

Phosphoenolpyruvate carboxylase

Gene

ppcA

Organism
Sulfolobus tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.UniRule annotation

Catalytic activityi

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-.UniRule annotation

Cofactori

Mg2+UniRule annotation

GO - Molecular functioni

  1. magnesium ion binding Source: UniProtKB-HAMAP
  2. phosphoenolpyruvate carboxylase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbon fixation Source: UniProtKB-HAMAP
  2. oxaloacetate metabolic process Source: UniProtKB-HAMAP
  3. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Lyase

Keywords - Biological processi

Carbon dioxide fixation

Keywords - Ligandi

Magnesium

Enzyme and pathway databases

BioCyciSTOK273063:GJC7-2309-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoenolpyruvate carboxylaseUniRule annotation (EC:4.1.1.31UniRule annotation)
Short name:
PEPCUniRule annotation
Short name:
PEPCaseUniRule annotation
Gene namesi
Name:ppcAUniRule annotation
Ordered Locus Names:STK_21010
OrganismiSulfolobus tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)
Taxonomic identifieri273063 [NCBI]
Taxonomic lineageiArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus
ProteomesiUP000001015 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 511511Phosphoenolpyruvate carboxylasePRO_0000309616Add
BLAST

Proteomic databases

PRIDEiQ96YS2.

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

STRINGi273063.ST2101.

Structurei

3D structure databases

ProteinModelPortaliQ96YS2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PEPCase type 2 family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1892.
HOGENOMiHOG000038601.
KOiK01595.
OMAiQSSFKYD.

Family and domain databases

HAMAPiMF_01904. PEPcase_type2.
InterProiIPR007566. PEP_COase_arc-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF14010. PEPcase_2. 1 hit.
[Graphical view]
PIRSFiPIRSF006677. UCP006677. 1 hit.
SUPFAMiSSF51621. SSF51621. 1 hit.
TIGRFAMsiTIGR02751. PEPCase_arch. 1 hit.

Sequencei

Sequence statusi: Complete.

Q96YS2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRKIPRTMST QHPDNARVPE WSRSEVISGE SEVIEAYLAY EHYEVDEVMW
60 70 80 90 100
DAEGKDVDTH VVRKLLTQYP EFFKEKILGR DIFLTYRIPN PKIEGAEKKV
110 120 130 140 150
FAETMESIPI TYDLAEKFFN TKPTPPVFEV ILPFTTDYKE LIAILKYYEV
160 170 180 190 200
AIVNKENVKL VDDIYVKDLI GEINPKSIEI IPLIEDRDSM FKIDQIVGEY
210 220 230 240 250
IKAMKPPYMR VFLARSDPAM NYGLISAVLS VKYALNRLGK IEKKYGIKIF
260 270 280 290 300
PLIGVGSLPF RGHFNPMNFE KVIDEYRGVY TFTVQSAFKY DYEDNEVINA
310 320 330 340 350
IRKINEREIS EFELLDEEEE KILHRIANVY TSSYQPIIES LADVINKIAL
360 370 380 390 400
FLPRRRARKL HIGLFGYSRS TGKVTLPRAI TFTGALYSIG IPPELIGISS
410 420 430 440 450
LSTLTEKEWN VLEKNYKYIK HDLQAAARFV SYESIDLMKE TWNVNEEIIK
460 470 480 490 500
KIMEDLSYAE NTLNIKIGDS NSVGRKHALI SSLALIALKE GNIDEAKSYL
510
LEMAKIRKSL G
Length:511
Mass (Da):58,839
Last modified:November 30, 2001 - v1
Checksum:i95930EE53A0623ED
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000023 Genomic DNA. Translation: BAB67205.1.
RefSeqiNP_378096.1. NC_003106.2.
WP_010980180.1. NC_003106.2.

Genome annotation databases

EnsemblBacteriaiBAB67205; BAB67205; STK_21010.
GeneIDi1460173.
KEGGisto:ST2101.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000023 Genomic DNA. Translation: BAB67205.1.
RefSeqiNP_378096.1. NC_003106.2.
WP_010980180.1. NC_003106.2.

3D structure databases

ProteinModelPortaliQ96YS2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi273063.ST2101.

Proteomic databases

PRIDEiQ96YS2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAB67205; BAB67205; STK_21010.
GeneIDi1460173.
KEGGisto:ST2101.

Phylogenomic databases

eggNOGiCOG1892.
HOGENOMiHOG000038601.
KOiK01595.
OMAiQSSFKYD.

Enzyme and pathway databases

BioCyciSTOK273063:GJC7-2309-MONOMER.

Family and domain databases

HAMAPiMF_01904. PEPcase_type2.
InterProiIPR007566. PEP_COase_arc-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamiPF14010. PEPcase_2. 1 hit.
[Graphical view]
PIRSFiPIRSF006677. UCP006677. 1 hit.
SUPFAMiSSF51621. SSF51621. 1 hit.
TIGRFAMsiTIGR02751. PEPCase_arch. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: DSM 16993 / JCM 10545 / NBRC 100140 / 7.

Entry informationi

Entry nameiCAPPA_SULTO
AccessioniPrimary (citable) accession number: Q96YS2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 12, 2007
Last sequence update: November 30, 2001
Last modified: March 3, 2015
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.