Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q96YC2 (PGMI_SULTO) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Bifunctional phosphoglucose/phosphomannose isomerase
Alternative name(s):
Glucose-6-phosphate isomerase
Short name=GPI
EC=5.3.1.9
Mannose-6-phosphate isomerase
EC=5.3.1.8
Phosphoglucose isomerase
Short name=PGI
Phosphomannose isomerase
Short name=PMI
Gene names
Ordered Locus Names:STK_22450
OrganismSulfolobus tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) [Complete proteome] [HAMAP]
Taxonomic identifier273063 [NCBI]
Taxonomic lineageArchaeaCrenarchaeotaThermoproteiSulfolobalesSulfolobaceaeSulfolobus

Protein attributes

Sequence length311 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the isomerization of both glucose 6-phosphate and epimeric mannose 6-phosphate at a similar catalytic efficiency By similarity.

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate.

D-mannose 6-phosphate = D-fructose 6-phosphate.

Subunit structure

Homodimer By similarity.

Sequence similarities

Belongs to the PGI/PMI family.

Contains 1 SIS domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 311311Bifunctional phosphoglucose/phosphomannose isomerase
PRO_0000227797

Regions

Domain19 – 141123SIS

Sites

Active site1981Proton acceptor By similarity
Active site2141Proton donor By similarity
Active site2941Proton acceptor Probable

Sequences

Sequence LengthMass (Da)Tools
Q96YC2 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: 7539CA4B9C7C6328

FASTA31135,140
        10         20         30         40         50         60 
MNNPYENWIN FFQEALNTNI PSIEKIEELV YLGIGGSGIP GRILEILELP VKYQLFRGYK 

        70         80         90        100        110        120 
VKVNEKSTVI AVSYSGNTTE TIFALLTSLK KTRKAIVITS GGKIEEIASK HNLPVIKLPK 

       130        140        150        160        170        180 
GLQTRFVFPY IFTYLIRIIN EGLGTNYNVN ELVEGIKDYS KLNEISGILA SQIIGKIPII 

       190        200        210        220        230        240 
YSSTFLPIAE RFKQEINENA KYPAFYNELP EANHNEIELY SYPSPYTFYP IVIVSDKLDE 

       250        260        270        280        290        300 
ESANLINAYK IYPLYQSILK NIASLTLLAG LTSVKLAMLL GVKPEQLNII PKIREKTFKL 

       310 
FEGDINADQN L 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BA000023 Genomic DNA. Translation: BAK54769.1.
RefSeqNP_378246.1. NC_003106.2.

3D structure databases

ProteinModelPortalQ96YC2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING273063.ST2245.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAK54769; BAK54769; STK_22450.
GeneID1460327.
KEGGsto:ST2245.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000270998.
KOK15916.
OMAPYENWIN.

Enzyme and pathway databases

BioCycSTOK273063:GJC7-2463-MONOMER.

Family and domain databases

InterProIPR011857. Glu6P/Mann6P_isomerase.
IPR019490. Glu6P/Mann6P_isomerase_C.
IPR001347. SIS.
[Graphical view]
PfamPF10432. bact-PGI_C. 1 hit.
[Graphical view]
TIGRFAMsTIGR02128. G6PI_arch. 1 hit.
PROSITEPS51464. SIS. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePGMI_SULTO
AccessionPrimary (citable) accession number: Q96YC2
Secondary accession number(s): F9VPC2
Entry history
Integrated into UniProtKB/Swiss-Prot: March 21, 2006
Last sequence update: December 1, 2001
Last modified: May 14, 2014
This is version 63 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families