Q96WS1 (MEU24_SCHPO) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Meiotic expression up-regulated protein 24

Gene names

Name:	meu24
Synonyms:	wtf11
ORF Names:	SPCC1281.08

Organism

Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) [Reference proteome]

Taxonomic identifier

284812 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces › Schizosaccharomyces pombe

Protein attributes

Sequence length	264 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Subcellular location	Membrane; Multi-pass membrane protein Potential.
Sequence similarities	Belongs to the WTF family.

Ontologies

Keywords
Biological process	Meiosis
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	meiosis Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	Golgi apparatus Inferred from direct assay PubMed 16823372. Source: PomBase integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 264	264	Meiotic expression up-regulated protein 24		PRO_0000193220
Regions
	Transmembrane	107 – 127	21	Helical; Potential
	Transmembrane	145 – 165	21	Helical; Potential
	Transmembrane	180 – 200	21	Helical; Potential
	Transmembrane	217 – 237	21	Helical; Potential

Sequences

	Sequence		Length	Mass (Da)
	Q96WS1 [UniParc]. Last modified July 11, 2002. Version 2. Checksum: C3757C87EAB6FD62	FASTA	264	29,937
	10 20 30 40 50 60 MNSNYVPLTS SVDVEEKMES ENGVDLGNDI DLEKGLPLKY NSENESGLPS NSASSYLINP 70 80 90 100 110 120 DPTMDLEAQT FNHNESTTSV GHDNSNSPPK CRKTCSSNKV YSNEVPLLFV FVISISIVCI 130 140 150 160 170 180 FDLVIFGCLQ YNMVSMDDLH VMQRLSWFCA SLALLFILMR YYDFWTKACK DGIKHIFKKW 190 200 210 220 230 240 KNTPLAFLQV LIFNIIGFFV RKGLKDSFGE QWGLKTSLFA HVSFATMSIF IFIFETLKPG 250 260 SCSVDWIARI LKAVVYFLED SDEL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genome sequence of Schizosaccharomyces pombe." Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P. Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 972 / ATCC 24843.
[2]	"Comprehensive isolation of meiosis-specific genes identifies novel proteins and unusual non-coding transcripts in Schizosaccharomyces pombe." Watanabe T., Miyashita K., Saito T.T., Yoneki T., Kakihara Y., Nabeshima K., Kishi Y.A., Shimoda C., Nojima H. Nucleic Acids Res. 29:2327-2337(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 236-264. Strain: CD16-1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CU329672 Genomic DNA. Translation: CAA22829.1. AB054308 mRNA. Translation: BAB60875.1.
PIR	T40927.
RefSeq	NP_588172.1. NM_001023161.2.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
MINT	MINT-4701648.
STRING	4896.SPCC1281.08-1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblFungi	SPCC1281.08.1; SPCC1281.08.1:pep; SPCC1281.08.
GeneID	2539167.
KEGG	spo:SPCC1281.08.
Organism-specific databases
PomBase	SPCC1281.08.
Family and domain databases
InterPro	IPR004982. WTF. [Graphical view]
Pfam	PF03303. WTF. 1 hit. [Graphical view]
PROSITE	PS00014. ER_TARGET. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	20800338.

Entry information

Entry name

MEU24_SCHPO

Accession

Primary (citable) accession number: Q96WS1

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 11, 2002
Last sequence update:	July 11, 2002
Last modified:	May 29, 2013
This is version 66 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program