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Protein

Alpha,alpha-trehalose-phosphate synthase [UDP-forming]

Gene

TPS1

Organism
Zygosaccharomyces rouxii (Candida mogii)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

UDP-glucose + D-glucose 6-phosphate = UDP + alpha,alpha-trehalose 6-phosphate.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGlycosyltransferase, Transferase

Protein family/group databases

CAZyiGT20. Glycosyltransferase Family 20.

Names & Taxonomyi

Protein namesi
Recommended name:
Alpha,alpha-trehalose-phosphate synthase [UDP-forming] (EC:2.4.1.15)
Alternative name(s):
Trehalose-6-phosphate synthase
UDP-glucose-glucosephosphate glucosyltransferase
Gene namesi
Name:TPS1
OrganismiZygosaccharomyces rouxii (Candida mogii)
Taxonomic identifieri4956 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeZygosaccharomyces

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001225031 – 485Alpha,alpha-trehalose-phosphate synthase [UDP-forming]Add BLAST485

Structurei

3D structure databases

ProteinModelPortaliQ96WK6.
SMRiQ96WK6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 20 family.Curated

Phylogenomic databases

eggNOGiKOG1050. Eukaryota.
COG0380. LUCA.

Family and domain databases

CDDicd03788. GT1_TPS. 1 hit.
InterProiView protein in InterPro
IPR001830. Glyco_trans_20.
IPR012766. Trehalose_OtsA.
PfamiView protein in Pfam
PF00982. Glyco_transf_20. 1 hit.
TIGRFAMsiTIGR02400. trehalose_OtsA. 1 hit.

Sequencei

Sequence statusi: Complete.

Q96WK6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTVSKKDSGK TSPGNIVVVS NRLPVTISKN AMGKYEYKFS SGGLVTALQG
60 70 80 90 100
LKKTSTFQWY GWPSLEIPDD EKPVVKKDLL EKFNAIPIFL SDEIADLHYN
110 120 130 140 150
GFSNSILWPL FHYHPGEINF DENAWLAYNE ANATFASEIC GNLQDNDLVW
160 170 180 190 200
VHDYHLMLLP EMLSAHIQRK GLKNIKLGWF LHTPFPSSEI YRILPVRQEI
210 220 230 240 250
LNGVLSCDLI GFHTYDYARH FLSSIQRCLN VNTLPNGVEY QGRFVNVGAF
260 270 280 290 300
PIGIDVDTFK EGLQKENVKQ RIRTLQERFK GCKIMVGVDR LDYIKGVPQK
310 320 330 340 350
LHAMEVFLNE HPEWIGKVVL VQLAIPSRGD VEEYQYLRSV VNELVGRING
360 370 380 390 400
QFGTIEFVPI HFMHKSIPFE ELISLYAVSD ACIVSSTRDG MNLVSYEYIA
410 420 430 440 450
CRKKGSLILS EFTGAAQSLN GALIVNPWNT DELSDSINEA LTLPDEKKDS
460 470 480
NWEKLYKYIS KYTSAYWGEN FVHELNATGT IKTGQ
Length:485
Mass (Da):55,022
Last modified:December 1, 2001 - v1
Checksum:iDBDD486C7AF4A8CF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF276078 mRNA. Translation: AAK69413.1.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiTPS1_ZYGRO
AccessioniPrimary (citable) accession number: Q96WK6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 6, 2002
Last sequence update: December 1, 2001
Last modified: July 5, 2017
This is version 43 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families