ID   DHE4_GIBFU              Reviewed;         451 AA.
AC   Q96VJ7;
DT   16-JAN-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   16-JUN-2009, entry version 34.
DE   RecName: Full=NADP-specific glutamate dehydrogenase;
DE            Short=NADP-GDH;
DE            EC=1.4.1.4;
DE   AltName: Full=NADP-dependent glutamate dehydrogenase;
GN   Name=GDH2;
OS   Gibberella fujikuroi (Bakanae and foot rot disease fungus) (Fusarium
OS   moniliforme).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina;
OC   Sordariomycetes; Hypocreomycetidae; Hypocreales; Nectriaceae;
OC   Gibberella; Gibberella fujikuroi complex.
OX   NCBI_TaxID=5127;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=m567;
RA   Tudzynski B.;
RT   "Cloning and characterization of the NADP-depending glutamate
RT   dehydrogenase gene from Gibberella fujikuroi.";
RL   Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: L-glutamate + H(2)O + NADP(+) = 2-oxoglutarate
CC       + NH(3) + NADPH.
CC   -!- SUBUNIT: Homohexamer (By similarity).
CC   -!- SIMILARITY: Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
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DR   EMBL; AJ315471; CAC45043.1; -; Genomic_DNA.
DR   HSSP; P24295; 1AUP.
DR   BRENDA; 1.4.1.4; 97815.
DR   GO; GO:0005488; F:binding; IEA:InterPro.
DR   GO; GO:0004354; F:glutamate dehydrogenase (NADP+) activity; IEA:EC.
DR   GO; GO:0006520; P:amino acid metabolic process; IEA:InterPro.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   InterPro; IPR006095; Glu/Leu/Phe/Val_DH.
DR   InterPro; IPR006096; Glu/Leu/Phe/Val_DH_C.
DR   InterPro; IPR006097; Glu/Leu/Phe/Val_DH_dimer.
DR   InterPro; IPR014362; Glu_DH.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   Gene3D; G3DSA:3.40.50.720; NAD(P)-bd; 1.
DR   PANTHER; PTHR11606:SF2; GLFV_DH; 1.
DR   Pfam; PF00208; ELFV_dehydrog; 1.
DR   Pfam; PF02812; ELFV_dehydrog_N; 1.
DR   PIRSF; PIRSF000185; Glu_DH; 1.
DR   PRINTS; PR00082; GLFDHDRGNASE.
DR   PROSITE; PS00074; GLFV_DEHYDROGENASE; 1.
PE   3: Inferred from homology;
KW   NADP; Oxidoreductase.
FT   CHAIN         1    451       NADP-specific glutamate dehydrogenase.
FT                                /FTId=PRO_0000182787.
FT   ACT_SITE    114    114       By similarity.
SQ   SEQUENCE   451 AA;  48826 MW;  171867950A9B8E85 CRC64;
     MSHLPQEPEF EQAYGELASA LENSSLFNEH PEYRTALAVA AIPERVIQFR VVWNDDKGNL
     QVNRGYRVQF NGALGPYKGG LRFHPSVNLS ILKFLGFEQI FKNALTGLNM GGGKGGADFD
     PKGKSDAEIR RFCQAFMTEL SKHIGAETDV PAGDIGVGGR EIGYLFGAYR KFANRWEGVL
     TGKGLSWGGS LIRPEATGYG LVYYVEYMLK HANRGTFEGK RVALSGSGNV AQYAALKIIE
     LGGSVVSLSD SKGALVAKEG SSFTPEQIHN IAALKIKHQA LTTFEHDGQF TWIEGARPWV
     HVGKVDIALP SATQNEVSKE EAQALVDAGA FIVAEGSNMG CTAEAIDVFE AHRKEKGAEA
     LWYAPGKASN CGGVAVSGLE MAQNSQRIQW TEKEVDDRLK AIMKDAFVAG LETAQKYVEA
     KEGELPSLIA GSNIAGFIKV AEAMHDQGDW F
//