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Q96VJ7 (DHE4_GIBFU) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 54. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
NADP-specific glutamate dehydrogenase

Short name=NADP-GDH
EC=1.4.1.4
Alternative name(s):
NADP-dependent glutamate dehydrogenase
Gene names
Name:GDH2
OrganismGibberella fujikuroi (Bakanae and foot rot disease fungus) (Fusarium fujikuroi)
Taxonomic identifier5127 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaSordariomycetesHypocreomycetidaeHypocrealesNectriaceaemitosporic NectriaceaeFusariumFusarium fujikuroi species complex

Protein attributes

Sequence length451 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

L-glutamate + H2O + NADP+ = 2-oxoglutarate + NH3 + NADPH.

Subunit structure

Homohexamer By similarity.

Sequence similarities

Belongs to the Glu/Leu/Phe/Val dehydrogenases family.

Ontologies

Keywords
   LigandNADP
   Molecular functionOxidoreductase
Gene Ontology (GO)
   Biological_processcellular amino acid metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionglutamate dehydrogenase (NADP+) activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 451451NADP-specific glutamate dehydrogenase
PRO_0000182787

Sites

Active site1141 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q96VJ7 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: 171867950A9B8E85

FASTA45148,826
        10         20         30         40         50         60 
MSHLPQEPEF EQAYGELASA LENSSLFNEH PEYRTALAVA AIPERVIQFR VVWNDDKGNL 

        70         80         90        100        110        120 
QVNRGYRVQF NGALGPYKGG LRFHPSVNLS ILKFLGFEQI FKNALTGLNM GGGKGGADFD 

       130        140        150        160        170        180 
PKGKSDAEIR RFCQAFMTEL SKHIGAETDV PAGDIGVGGR EIGYLFGAYR KFANRWEGVL 

       190        200        210        220        230        240 
TGKGLSWGGS LIRPEATGYG LVYYVEYMLK HANRGTFEGK RVALSGSGNV AQYAALKIIE 

       250        260        270        280        290        300 
LGGSVVSLSD SKGALVAKEG SSFTPEQIHN IAALKIKHQA LTTFEHDGQF TWIEGARPWV 

       310        320        330        340        350        360 
HVGKVDIALP SATQNEVSKE EAQALVDAGA FIVAEGSNMG CTAEAIDVFE AHRKEKGAEA 

       370        380        390        400        410        420 
LWYAPGKASN CGGVAVSGLE MAQNSQRIQW TEKEVDDRLK AIMKDAFVAG LETAQKYVEA 

       430        440        450 
KEGELPSLIA GSNIAGFIKV AEAMHDQGDW F 

« Hide

References

[1]"Cloning and characterization of the NADP-depending glutamate dehydrogenase gene from Gibberella fujikuroi."
Tudzynski B.
Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: m567.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ315471 Genomic DNA. Translation: CAC45043.1.

3D structure databases

ProteinModelPortalQ96VJ7.
SMRQ96VJ7. Positions 4-450.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEQ96VJ7.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D3.40.50.720. 1 hit.
InterProIPR006095. Glu/Leu/Phe/Val_DH.
IPR006096. Glu/Leu/Phe/Val_DH_C.
IPR006097. Glu/Leu/Phe/Val_DH_dimer_dom.
IPR014362. Glu_DH.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamPF00208. ELFV_dehydrog. 1 hit.
PF02812. ELFV_dehydrog_N. 1 hit.
[Graphical view]
PIRSFPIRSF000185. Glu_DH. 1 hit.
PRINTSPR00082. GLFDHDRGNASE.
SMARTSM00839. ELFV_dehydrog. 1 hit.
[Graphical view]
PROSITEPS00074. GLFV_DEHYDROGENASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDHE4_GIBFU
AccessionPrimary (citable) accession number: Q96VJ7
Entry history
Integrated into UniProtKB/Swiss-Prot: January 16, 2004
Last sequence update: December 1, 2001
Last modified: November 13, 2013
This is version 54 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families