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Q96UJ9

- DHE4_HEBCY

UniProt

Q96UJ9 - DHE4_HEBCY

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Protein
NADP-specific glutamate dehydrogenase
Gene
N/A
Organism
Hebeloma cylindrosporum
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

Catalytic activityi

L-glutamate + H2O + NADP+ = 2-oxoglutarate + NH3 + NADPH.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei111 – 1111 By similarity

GO - Molecular functioni

  1. glutamate dehydrogenase (NADP+) activity Source: UniProtKB-EC
Complete GO annotation...

GO - Biological processi

  1. cellular amino acid metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

NADP

Names & Taxonomyi

Protein namesi
Recommended name:
NADP-specific glutamate dehydrogenase (EC:1.4.1.4)
Short name:
NADP-GDH
Alternative name(s):
NADP-dependent glutamate dehydrogenase
OrganismiHebeloma cylindrosporum
Taxonomic identifieri76867 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaBasidiomycotaAgaricomycotinaAgaricomycetesAgaricomycetidaeAgaricalesCortinariaceaeHebeloma

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 450450NADP-specific glutamate dehydrogenase
PRO_0000182788Add
BLAST

Proteomic databases

PRIDEiQ96UJ9.

Interactioni

Subunit structurei

Homohexamer By similarity.

Structurei

3D structure databases

ProteinModelPortaliQ96UJ9.
SMRiQ96UJ9. Positions 3-449.

Family & Domainsi

Sequence similaritiesi

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR006095. Glu/Leu/Phe/Val_DH.
IPR006096. Glu/Leu/Phe/Val_DH_C.
IPR006097. Glu/Leu/Phe/Val_DH_dimer_dom.
IPR014362. Glu_DH.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF00208. ELFV_dehydrog. 1 hit.
PF02812. ELFV_dehydrog_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000185. Glu_DH. 1 hit.
PRINTSiPR00082. GLFDHDRGNASE.
SMARTiSM00839. ELFV_dehydrog. 1 hit.
[Graphical view]
PROSITEiPS00074. GLFV_DEHYDROGENASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q96UJ9-1 [UniParc]FASTAAdd to Basket

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MVKPFEPEFQ QALDELTTSL QPFLDANPQY KKALEIVQVP ERVLQFRVVW    50
EDDQGVAQVN HGFRVQYNSA LGPYKGGLRL HPSVNLSILK FLGFEQTFKN 100
ALTGLSMGGG KGGSDFDPKG KSDSEIRRFC FSFMGELFRH IGSDTDVPAG 150
DIGTGGREIG FLFGAYKKLR NEFTGMLTGK GLTWGGSFIR PEATGYGLIY 200
FVEHMIAKAC PEYSLDKPST LVAISGSGNV AQFTALKVIE LGATVLSLSD 250
SKGSLISDKG YTKEFIRKVA DLKLKGGSLA SLANEEGYTY HAGARPWTLI 300
PTIHIALPGA TQNEVSAEEA EALLKAGVRI VAEGSNMGCT ADAIDIFESS 350
RKAGPGGVWY APGKASNCGG VAVSGLEMAQ NSQRLAWTTQ EVDSKLKDIM 400
AECYGICLTA GTKWSGEELT DEVLPSLLSG ANVAGFIKVA DAMKAQGDWW 450
Length:450
Mass (Da):48,356
Last modified:December 1, 2001 - v1
Checksum:i3D0E79953F3E0746
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY052476 mRNA. Translation: AAL06075.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AY052476 mRNA. Translation: AAL06075.1 .

3D structure databases

ProteinModelPortali Q96UJ9.
SMRi Q96UJ9. Positions 3-449.
ModBasei Search...

Proteomic databases

PRIDEi Q96UJ9.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 3.40.50.720. 1 hit.
InterProi IPR006095. Glu/Leu/Phe/Val_DH.
IPR006096. Glu/Leu/Phe/Val_DH_C.
IPR006097. Glu/Leu/Phe/Val_DH_dimer_dom.
IPR014362. Glu_DH.
IPR016040. NAD(P)-bd_dom.
[Graphical view ]
Pfami PF00208. ELFV_dehydrog. 1 hit.
PF02812. ELFV_dehydrog_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF000185. Glu_DH. 1 hit.
PRINTSi PR00082. GLFDHDRGNASE.
SMARTi SM00839. ELFV_dehydrog. 1 hit.
[Graphical view ]
PROSITEi PS00074. GLFV_DEHYDROGENASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Nucleotide sequence and expression of NADP(+)-GDH and GS from the ectomycorrhizal fungus Hebeloma cylindrosporum."
    Rodriguez-Pastrana B., Javelle A., Belleville R., Morel M., Botton B., Jacob C., Chalot M., Brun A.
    Submitted (AUG-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: h1.

Entry informationi

Entry nameiDHE4_HEBCY
AccessioniPrimary (citable) accession number: Q96UJ9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 16, 2004
Last sequence update: December 1, 2001
Last modified: October 16, 2013
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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