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Q96UJ9

- DHE4_HEBCY

UniProt

Q96UJ9 - DHE4_HEBCY

Protein

NADP-specific glutamate dehydrogenase

Gene
N/A
Organism
Hebeloma cylindrosporum
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 51 (01 Oct 2014)
      Sequence version 1 (01 Dec 2001)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    L-glutamate + H2O + NADP+ = 2-oxoglutarate + NH3 + NADPH.

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei111 – 1111PROSITE-ProRule annotation

    GO - Molecular functioni

    1. glutamate dehydrogenase (NADP+) activity Source: UniProtKB-EC

    GO - Biological processi

    1. cellular amino acid metabolic process Source: InterPro

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Ligandi

    NADP

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    NADP-specific glutamate dehydrogenase (EC:1.4.1.4)
    Short name:
    NADP-GDH
    Alternative name(s):
    NADP-dependent glutamate dehydrogenase
    OrganismiHebeloma cylindrosporum
    Taxonomic identifieri76867 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaBasidiomycotaAgaricomycotinaAgaricomycetesAgaricomycetidaeAgaricalesCortinariaceaeHebeloma

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 450450NADP-specific glutamate dehydrogenasePRO_0000182788Add
    BLAST

    Proteomic databases

    PRIDEiQ96UJ9.

    Interactioni

    Subunit structurei

    Homohexamer.By similarity

    Structurei

    3D structure databases

    ProteinModelPortaliQ96UJ9.
    SMRiQ96UJ9. Positions 3-449.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Family and domain databases

    Gene3Di3.40.50.720. 1 hit.
    InterProiIPR006095. Glu/Leu/Phe/Val_DH.
    IPR006096. Glu/Leu/Phe/Val_DH_C.
    IPR006097. Glu/Leu/Phe/Val_DH_dimer_dom.
    IPR014362. Glu_DH.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view]
    PfamiPF00208. ELFV_dehydrog. 1 hit.
    PF02812. ELFV_dehydrog_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000185. Glu_DH. 1 hit.
    PRINTSiPR00082. GLFDHDRGNASE.
    SMARTiSM00839. ELFV_dehydrog. 1 hit.
    [Graphical view]
    PROSITEiPS00074. GLFV_DEHYDROGENASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q96UJ9-1 [UniParc]FASTAAdd to Basket

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    MVKPFEPEFQ QALDELTTSL QPFLDANPQY KKALEIVQVP ERVLQFRVVW    50
    EDDQGVAQVN HGFRVQYNSA LGPYKGGLRL HPSVNLSILK FLGFEQTFKN 100
    ALTGLSMGGG KGGSDFDPKG KSDSEIRRFC FSFMGELFRH IGSDTDVPAG 150
    DIGTGGREIG FLFGAYKKLR NEFTGMLTGK GLTWGGSFIR PEATGYGLIY 200
    FVEHMIAKAC PEYSLDKPST LVAISGSGNV AQFTALKVIE LGATVLSLSD 250
    SKGSLISDKG YTKEFIRKVA DLKLKGGSLA SLANEEGYTY HAGARPWTLI 300
    PTIHIALPGA TQNEVSAEEA EALLKAGVRI VAEGSNMGCT ADAIDIFESS 350
    RKAGPGGVWY APGKASNCGG VAVSGLEMAQ NSQRLAWTTQ EVDSKLKDIM 400
    AECYGICLTA GTKWSGEELT DEVLPSLLSG ANVAGFIKVA DAMKAQGDWW 450
    Length:450
    Mass (Da):48,356
    Last modified:December 1, 2001 - v1
    Checksum:i3D0E79953F3E0746
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY052476 mRNA. Translation: AAL06075.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY052476 mRNA. Translation: AAL06075.1 .

    3D structure databases

    ProteinModelPortali Q96UJ9.
    SMRi Q96UJ9. Positions 3-449.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q96UJ9.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    Gene3Di 3.40.50.720. 1 hit.
    InterProi IPR006095. Glu/Leu/Phe/Val_DH.
    IPR006096. Glu/Leu/Phe/Val_DH_C.
    IPR006097. Glu/Leu/Phe/Val_DH_dimer_dom.
    IPR014362. Glu_DH.
    IPR016040. NAD(P)-bd_dom.
    [Graphical view ]
    Pfami PF00208. ELFV_dehydrog. 1 hit.
    PF02812. ELFV_dehydrog_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000185. Glu_DH. 1 hit.
    PRINTSi PR00082. GLFDHDRGNASE.
    SMARTi SM00839. ELFV_dehydrog. 1 hit.
    [Graphical view ]
    PROSITEi PS00074. GLFV_DEHYDROGENASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Nucleotide sequence and expression of NADP(+)-GDH and GS from the ectomycorrhizal fungus Hebeloma cylindrosporum."
      Rodriguez-Pastrana B., Javelle A., Belleville R., Morel M., Botton B., Jacob C., Chalot M., Brun A.
      Submitted (AUG-2001) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Strain: h1.

    Entry informationi

    Entry nameiDHE4_HEBCY
    AccessioniPrimary (citable) accession number: Q96UJ9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 16, 2004
    Last sequence update: December 1, 2001
    Last modified: October 1, 2014
    This is version 51 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3