##gff-version 3
Q96TA2	UniProtKB	Chain	1	773	.	.	.	ID=PRO_0000084667;Note=ATP-dependent zinc metalloprotease YME1L1	
Q96TA2	UniProtKB	Topological domain	1	295	.	.	.	Note=Mitochondrial matrix;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q96TA2	UniProtKB	Transmembrane	296	316	.	.	.	Note=Helical;Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q96TA2	UniProtKB	Topological domain	317	773	.	.	.	Note=Mitochondrial intermembrane;Ontology_term=ECO:0000305;evidence=ECO:0000305|PubMed:27786171;Dbxref=PMID:27786171	
Q96TA2	UniProtKB	Active site	600	600	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P0AAI3	
Q96TA2	UniProtKB	Binding site	379	386	.	.	.	Ontology_term=ECO:0000255;evidence=ECO:0000255	
Q96TA2	UniProtKB	Binding site	599	599	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P0AAI3	
Q96TA2	UniProtKB	Binding site	603	603	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P0AAI3	
Q96TA2	UniProtKB	Binding site	677	677	.	.	.	Ontology_term=ECO:0000250;evidence=ECO:0000250|UniProtKB:P0AAI3	
Q96TA2	UniProtKB	Alternative sequence	57	113	.	.	.	ID=VSP_010017;Note=In isoform 2 and isoform 3. Missing;Ontology_term=ECO:0000303,ECO:0000303,ECO:0000303,ECO:0000303;evidence=ECO:0000303|PubMed:10843804,ECO:0000303|PubMed:12975309,ECO:0000303|PubMed:14702039,ECO:0000303|PubMed:15489334;Dbxref=PMID:10843804,PMID:12975309,PMID:14702039,PMID:15489334	
Q96TA2	UniProtKB	Alternative sequence	168	200	.	.	.	ID=VSP_045336;Note=In isoform 3. Missing;Ontology_term=ECO:0000303;evidence=ECO:0000303|PubMed:14702039;Dbxref=PMID:14702039	
Q96TA2	UniProtKB	Natural variant	206	206	.	.	.	ID=VAR_076869;Note=In OPA11%3B does not affect localization to mitochondria%3B abolishes processing to mature form by MPP%3B results in decreased mitochondrial protein catabolism%3B has very low protease activity%3B results in mitochondrial fragmentation. R->W;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:27495975;Dbxref=dbSNP:rs1057519312,PMID:27495975	
Q96TA2	UniProtKB	Mutagenesis	439	439	.	.	.	Note=Loss of ATPase and protease activity. Loss of PRELID1 degradation. Cannot restore OMA1 degradation in YME1L-depleted cells. E->Q;Ontology_term=ECO:0000269,ECO:0000269,ECO:0000269;evidence=ECO:0000269|PubMed:26923599,ECO:0000269|PubMed:27495975,ECO:0000269|PubMed:27786171;Dbxref=PMID:26923599,PMID:27495975,PMID:27786171	
Q96TA2	UniProtKB	Mutagenesis	600	600	.	.	.	Note=Loss of protease activity. Cannot restore OMA1 degradation in YME1L-depleted cells. E->Q;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:26923599;Dbxref=PMID:26923599	
Q96TA2	UniProtKB	Sequence conflict	12	12	.	.	.	Note=V->F;Ontology_term=ECO:0000305;evidence=ECO:0000305