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Protein

MAP7 domain-containing protein 2

Gene

MAP7D2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
MAP7 domain-containing protein 2
Gene namesi
Name:MAP7D2
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome X

Organism-specific databases

HGNCiHGNC:25899. MAP7D2.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA162394971.

Polymorphism and mutation databases

BioMutaiMAP7D2.
DMDMi296434580.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 732732MAP7 domain-containing protein 2PRO_0000306809Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Isoform 5 (identifier: Q96T17-5)
Modified residuei1 – 11N-acetylmethionineCombined sources

Keywords - PTMi

Acetylation

Proteomic databases

MaxQBiQ96T17.
PRIDEiQ96T17.

PTM databases

iPTMnetiQ96T17.
PhosphoSiteiQ96T17.

Expressioni

Gene expression databases

BgeeiQ96T17.
CleanExiHS_MAP7D2.
GenevisibleiQ96T17. HS.

Organism-specific databases

HPAiHPA051508.

Interactioni

Protein-protein interaction databases

BioGridi129178. 25 interactions.
IntActiQ96T17. 7 interactions.
MINTiMINT-8329993.

Structurei

3D structure databases

ProteinModelPortaliQ96T17.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili51 – 14696Sequence analysisAdd
BLAST

Sequence similaritiesi

Belongs to the MAP7 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

GeneTreeiENSGT00660000095160.
HOGENOMiHOG000232157.
HOVERGENiHBG055348.
InParanoidiQ96T17.
OMAiDPKVELQ.
OrthoDBiEOG76X5ZS.
PhylomeDBiQ96T17.
TreeFamiTF332273.

Family and domain databases

InterProiIPR008604. MAP7_fam.
[Graphical view]
PANTHERiPTHR15073. PTHR15073. 1 hit.
PfamiPF05672. MAP7. 1 hit.
[Graphical view]

Sequences (5)i

Sequence statusi: Complete.

This entry describes 5 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q96T17-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MERGGGGSGT GSRPEGTARG TSLPGKIAEP GAVRTSQPNY RPQGMEGFLK
60 70 80 90 100
SDERQRLAKE RREEREKCLA AREQQILEKQ KRARLQYEKQ MEERWRKLEE
110 120 130 140 150
QRQREDQKRA AVEEKRKQKL REEEERLEAM MRRSLERTQQ LELKKKYSWG
160 170 180 190 200
APLAIGPGGH DACDKLSTST MSLPKPTEPP MNKRLSSSTV AISYSPDRVF
210 220 230 240 250
HVCPRLAPLG PLNPSYKSSP TRNIEKKKAT STSTSGAGDV GKEALSGGEA
260 270 280 290 300
SLVEKVKRGQ RTATSLPVVN FGSPLRRCEF SGGIPKRPSS PVISKTATKA
310 320 330 340 350
YPQSPKTTKP PYPGSPVKYR LPALSGQDMP KRKAEKEKSN KEREGTLAQQ
360 370 380 390 400
AAGPQGEEAL EKHVVDKHAS EKHAAAAGGK AENSAALGKP TAGTTDAGEA
410 420 430 440 450
AKILAEKRRQ ARLQKEQEEQ ERLEKEEQDR LEREELKRKA EEERLRLEEE
460 470 480 490 500
ARKQEEERKR QEEEKKKQEG EEKRKAGEEA KRKAEEELLL KEKQEQEKQE
510 520 530 540 550
KAMIEKQKEA AETKAREVAE QMRLEREQIM LQIEQERLER KKRIDEIMKR
560 570 580 590 600
TRKSDVSPQV KKEDPKVGVQ PAVCVEKKTK LVVPNKMEIN GLNTCQEVNG
610 620 630 640 650
VDHAAPETYP QDIFSNGLKP AGGLIHLDAL DGKSNSLDDS TEEVQSMDVS
660 670 680 690 700
PVSKEELISI PEFSPVSEMI PGVSLDQNGT GNARALQDLL DFTGPPTFPK
710 720 730
RSSENLSLDD CNKNLIEGFN SPGQETPLNT FC
Length:732
Mass (Da):81,965
Last modified:May 18, 2010 - v2
Checksum:i9F3C004D6942F08E
GO
Isoform 2 (identifier: Q96T17-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     198-198: R → RAHHMHLSPMEAILVSRLLTPTQSSLARSRASVMLSGQANDS

Show »
Length:773
Mass (Da):86,349
Checksum:i22097F6CE24953C0
GO
Isoform 3 (identifier: Q96T17-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     161-161: D → DGESENTPPPPLGLAASTLPPDAGTTAAAAESTN
     198-201: RVFH → QAEG
     202-732: Missing.

Note: No experimental confirmation available.
Show »
Length:234
Mass (Da):26,071
Checksum:iA975E2E6AD4083AB
GO
Isoform 4 (identifier: Q96T17-4) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     162-206: Missing.

Note: No experimental confirmation available.
Show »
Length:687
Mass (Da):77,034
Checksum:iE1544B277C4FB5E2
GO
Isoform 5 (identifier: Q96T17-5) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-44: Missing.
     199-206: Missing.

Note: No experimental confirmation available.Combined sources
Show »
Length:680
Mass (Da):76,647
Checksum:i3E3721049F201381
GO

Sequence cautioni

The sequence BAC05407.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti14 – 141P → L in AAH89400 (PubMed:15489334).Curated
Sequence conflicti423 – 4231L → V in BAB55093 (PubMed:14702039).Curated
Sequence conflicti557 – 5571S → P in BAB55093 (PubMed:14702039).Curated
Sequence conflicti590 – 5901N → S in BAH11884 (PubMed:14702039).Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti32 – 321A → P in a breast cancer sample; somatic mutation. 1 Publication
VAR_035450
Natural varianti182 – 1821N → S.1 Publication
Corresponds to variant rs34519770 [ dbSNP | Ensembl ].
VAR_035313

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 4444Missing in isoform 5. 1 PublicationVSP_044657Add
BLAST
Alternative sequencei161 – 1611D → DGESENTPPPPLGLAASTLP PDAGTTAAAAESTN in isoform 3. 1 PublicationVSP_028490
Alternative sequencei162 – 20645Missing in isoform 4. 1 PublicationVSP_043337Add
BLAST
Alternative sequencei198 – 2014RVFH → QAEG in isoform 3. 1 PublicationVSP_028491
Alternative sequencei198 – 1981R → RAHHMHLSPMEAILVSRLLT PTQSSLARSRASVMLSGQAN DS in isoform 2. 1 PublicationVSP_028492
Alternative sequencei199 – 2068Missing in isoform 5. 1 PublicationVSP_044658
Alternative sequencei202 – 732531Missing in isoform 3. 1 PublicationVSP_028493Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK027409 mRNA. Translation: BAB55093.1.
AK098768 mRNA. Translation: BAC05407.1. Different initiation.
AK294788 mRNA. Translation: BAH11884.1.
AK296319 mRNA. Translation: BAH12313.1.
AL732366 Genomic DNA. Translation: CAI40549.1.
BC037165 mRNA. Translation: AAH37165.1.
BC089400 mRNA. Translation: AAH89400.1.
BC136379 mRNA. Translation: AAI36380.1.
CCDSiCCDS14195.1. [Q96T17-1]
CCDS55384.1. [Q96T17-5]
CCDS55385.1. [Q96T17-4]
CCDS55386.1. [Q96T17-2]
RefSeqiNP_001161937.1. NM_001168465.1. [Q96T17-2]
NP_001161938.1. NM_001168466.1. [Q96T17-4]
NP_001161939.1. NM_001168467.1. [Q96T17-5]
NP_689993.2. NM_152780.3. [Q96T17-1]
UniGeneiHs.127951.

Genome annotation databases

EnsembliENST00000379643; ENSP00000368964; ENSG00000184368. [Q96T17-2]
ENST00000379651; ENSP00000368972; ENSG00000184368. [Q96T17-1]
ENST00000443379; ENSP00000388239; ENSG00000184368. [Q96T17-4]
ENST00000452324; ENSP00000413301; ENSG00000184368. [Q96T17-5]
GeneIDi256714.
KEGGihsa:256714.
UCSCiuc004czr.3. human. [Q96T17-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK027409 mRNA. Translation: BAB55093.1.
AK098768 mRNA. Translation: BAC05407.1. Different initiation.
AK294788 mRNA. Translation: BAH11884.1.
AK296319 mRNA. Translation: BAH12313.1.
AL732366 Genomic DNA. Translation: CAI40549.1.
BC037165 mRNA. Translation: AAH37165.1.
BC089400 mRNA. Translation: AAH89400.1.
BC136379 mRNA. Translation: AAI36380.1.
CCDSiCCDS14195.1. [Q96T17-1]
CCDS55384.1. [Q96T17-5]
CCDS55385.1. [Q96T17-4]
CCDS55386.1. [Q96T17-2]
RefSeqiNP_001161937.1. NM_001168465.1. [Q96T17-2]
NP_001161938.1. NM_001168466.1. [Q96T17-4]
NP_001161939.1. NM_001168467.1. [Q96T17-5]
NP_689993.2. NM_152780.3. [Q96T17-1]
UniGeneiHs.127951.

3D structure databases

ProteinModelPortaliQ96T17.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi129178. 25 interactions.
IntActiQ96T17. 7 interactions.
MINTiMINT-8329993.

PTM databases

iPTMnetiQ96T17.
PhosphoSiteiQ96T17.

Polymorphism and mutation databases

BioMutaiMAP7D2.
DMDMi296434580.

Proteomic databases

MaxQBiQ96T17.
PRIDEiQ96T17.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000379643; ENSP00000368964; ENSG00000184368. [Q96T17-2]
ENST00000379651; ENSP00000368972; ENSG00000184368. [Q96T17-1]
ENST00000443379; ENSP00000388239; ENSG00000184368. [Q96T17-4]
ENST00000452324; ENSP00000413301; ENSG00000184368. [Q96T17-5]
GeneIDi256714.
KEGGihsa:256714.
UCSCiuc004czr.3. human. [Q96T17-1]

Organism-specific databases

CTDi256714.
GeneCardsiMAP7D2.
H-InvDBHIX0016691.
HGNCiHGNC:25899. MAP7D2.
HPAiHPA051508.
neXtProtiNX_Q96T17.
PharmGKBiPA162394971.
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00660000095160.
HOGENOMiHOG000232157.
HOVERGENiHBG055348.
InParanoidiQ96T17.
OMAiDPKVELQ.
OrthoDBiEOG76X5ZS.
PhylomeDBiQ96T17.
TreeFamiTF332273.

Miscellaneous databases

ChiTaRSiMAP7D2. human.
GenomeRNAii256714.
NextBioi92856.
PROiQ96T17.

Gene expression databases

BgeeiQ96T17.
CleanExiHS_MAP7D2.
GenevisibleiQ96T17. HS.

Family and domain databases

InterProiIPR008604. MAP7_fam.
[Graphical view]
PANTHERiPTHR15073. PTHR15073. 1 hit.
PfamiPF05672. MAP7. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 4 AND 5), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 67-732 (ISOFORM 3).
    Tissue: Brain, Teratocarcinoma and Thalamus.
  2. "The DNA sequence of the human X chromosome."
    Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D., Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L., Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C.
    , Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A., Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P., Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D., Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D., Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L., Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P., Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G., Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J., Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D., Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L., Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z., Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S., Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S., Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O., Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H., Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T., Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L., Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R., Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y., Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K., Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J., Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L., Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S., Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A., Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L., Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D., Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H., McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S., Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C., Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S., Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V., Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K., Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K., Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D., Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R., Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B., Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C., d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q., Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N., Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A., Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J., Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A., Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F., Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L., Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S., Rogers J., Bentley D.R.
    Nature 434:325-337(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2), VARIANT SER-182.
    Tissue: Liver, Lymph and Testis.
  4. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
    Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
    Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  5. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
    Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.C., Olsen J.V., Mann M.
    Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  6. Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1 (ISOFORM 5), IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  7. Cited for: VARIANT [LARGE SCALE ANALYSIS] PRO-32.

Entry informationi

Entry nameiMA7D2_HUMAN
AccessioniPrimary (citable) accession number: Q96T17
Secondary accession number(s): B7Z2J8
, B7Z3S7, B9EGC7, C9JMA4, C9JYW0, Q5EBN1, Q5JPS7, Q6PIC7, Q8N792
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 2, 2007
Last sequence update: May 18, 2010
Last modified: March 16, 2016
This is version 91 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.