Q96SZ6 (CK5P1_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
CDK5 regulatory subunit-associated protein 1

Alternative name(s):
CDK5 activator-binding protein C42

Gene names

Name:	CDK5RAP1
Synonyms:	C20orf34
ORF Names:	CGI-05, HSPC167

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	601 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Specifically inhibits CDK5 activation by CDK5R1.
Cofactor	Binds 2 4Fe-4S clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine By similarity.
Subunit structure	Interacts with CDK5R1 (p35 form). CDK5RAP1, CDK5RAP2 and CDK5RAP3 show competitive binding to CDK5R1. Forms a complex with CDK5R1 and CDK5. Ref.8
Tissue specificity	Widely expressed. Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Ref.7
Sequence similarities	Belongs to the methylthiotransferase family. MiaB subfamily. Contains 1 MTTase N-terminal domain. Contains 1 TRAM domain.
Sequence caution	The sequence AAD34147.1 differs from that shown. Reason: Frameshift at positions 3, 32, 128, 133 and 569. The sequence AAF29131.1 differs from that shown. Reason: Frameshift at positions 213, 244, 267 and 282. The sequence BAB55120.1 differs from that shown. Reason: Erroneous termination at position 500. Translated as Glu.

Ontologies

Keywords
Coding sequence diversity	Alternative splicing
Ligand	4Fe-4S Iron Iron-sulfur Metal-binding S-adenosyl-L-methionine
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	brain development Non-traceable author statement PubMed 10915792. Source: UniProtKB negative regulation of cyclin-dependent protein serine/threonine kinase activity Inferred from direct assay Ref.8. Source: UniProtKB regulation of neuron differentiation Non-traceable author statement Ref.7. Source: UniProtKB tRNA modification Inferred from electronic annotation. Source: InterPro
Cellular_component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular_function	4 iron, 4 sulfur cluster binding Inferred from electronic annotation. Source: UniProtKB-KW metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW protein kinase binding Non-traceable author statement Ref.7. Source: UniProtKB transferase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Binary interactions

With	Entry	#Exp.	IntAct	Notes
EXOSC3	Q9NQT5	1	EBI-372956,EBI-371866
EXOSC5	Q9NQT4	1	EBI-372956,EBI-371876

Alternative products

This entry describes 4 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q96SZ6-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Note: May be due to intron retention. No experimental confirmation available.

Isoform 2 (identifier: Q96SZ6-2)

The sequence of this isoform differs from the canonical sequence as follows:
     1-90: Missing.
     293-306: Missing.

Note: No experimental confirmation available.

Isoform 3 (identifier: Q96SZ6-3)

Also known as: a;

The sequence of this isoform differs from the canonical sequence as follows:
     293-306: Missing.

Isoform 4 (identifier: Q96SZ6-4)

The sequence of this isoform differs from the canonical sequence as follows:
     293-383: Missing.

Note: No experimental confirmation available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 601	601	CDK5 regulatory subunit-associated protein 1		PRO_0000141764
Regions
	Domain	100 – 220	121	MTTase N-terminal
	Domain	515 – 590	76	TRAM
	Region	22 – 157	136	CDK5 activation inhibition
	Region	475 – 586	112	CDK5R1-binding
Sites
	Metal binding	109	1	Iron-sulfur (4Fe-4S) By similarity
	Metal binding	145	1	Iron-sulfur (4Fe-4S) By similarity
	Metal binding	183	1	Iron-sulfur (4Fe-4S) By similarity
	Metal binding	258	1	Iron-sulfur (4Fe-4S-S-AdoMet) By similarity
	Metal binding	262	1	Iron-sulfur (4Fe-4S-S-AdoMet) By similarity
	Metal binding	265	1	Iron-sulfur (4Fe-4S-S-AdoMet) By similarity
Natural variations
	Alternative sequence	1 – 90	90	Missing in isoform 2.		VSP_007560
	Alternative sequence	293 – 383	91	Missing in isoform 4.		VSP_007561
	Alternative sequence	293 – 306	14	Missing in isoform 2 and isoform 3.		VSP_007562
Experimental info
	Sequence conflict	213	1	R → Q in AAH01215. Ref.6
	Sequence conflict	217	1	V → D Ref.2
	Sequence conflict	269	1	F → L in BAB55120. Ref.3
	Sequence conflict	282	1	I → T in BAB55120. Ref.3
	Sequence conflict	323	1	D → G in BAB55120. Ref.3
	Sequence conflict	464	1	V → A in BAB14760. Ref.3
	Sequence conflict	511	1	T → S in AAF29131. Ref.2
	Sequence conflict	579	1	Missing Ref.1
	Sequence conflict	585	1	R → K in BAB14760. Ref.3

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified June 16, 2003. Version 2. Checksum: 4AEBFD7DA5400902	FASTA	601	67,689
	10 20 30 40 50 60 MHPLQCVLQV QRSLGWGPLA SVSWLSLRMC RAHSSLSSTM CPSPERQEDG ARKDFSSRLA 70 80 90 100 110 120 AGPTFQHFLK SASAPQEKLS SEVEDPPPYL MMDELLGRQR KVYLETYGCQ MNVNDTEIAW 130 140 150 160 170 180 SILQKSGYLR TSNLQEADVI LLVTCSIREK AEQTIWNRLH QLKALKTRRP RSRVPLRIGI 190 200 210 220 230 240 LGCMAERLKE EILNREKMVD ILAGPDAYRD LPRLLAVAES GQQAANVLLS LDETYADVMP 250 260 270 280 290 300 VQTSASATSA FVSIMRGCDN MCSYCIVPFT RGRERSRPIA SILEEVKKLS EQVFLPPRPP 310 320 330 340 350 360 KVLGLQGLKE VTLLGQNVNS FRDNSEVQFN SAVPTNLSRG FTTNYKTKQG GLRFAHLLDQ 370 380 390 400 410 420 VSRVDPEMRI RFTSPHPKDF PDEVLQLIHE RDNICKQIHL PAQSGSSRVL EAMRRGYSRE 430 440 450 460 470 480 AYVELVHHIR ESIPGVSLSS DFIAGFCGET EEDHVQTVSL LREVQYNMGF LFAYSMRQKT 490 500 510 520 530 540 RAYHRLKDDV PEEVKLRRLE ELITIFREEA TKANQTSVGC TQLVLVEGLS KRSATDLCGR 550 560 570 580 590 600 NDGNLKVIFP DAEMEDVNNP GLRVRAQPGD YVLVKITSAS SQTLRGHVLC RTTLRDSSAY C
	Isoform 2 [UniParc]. Checksum: C8FFBA14A5C3EB09	FASTA	497	56,223
	10 20 30 40 50 60 MMDELLGRQR KVYLETYGCQ MNVNDTEIAW SILQKSGYLR TSNLQEADVI LLVTCSIREK 70 80 90 100 110 120 AEQTIWNRLH QLKALKTRRP RSRVPLRIGI LGCMAERLKE EILNREKMVD ILAGPDAYRD 130 140 150 160 170 180 LPRLLAVAES GQQAANVLLS LDETYADVMP VQTSASATSA FVSIMRGCDN MCSYCIVPFT 190 200 210 220 230 240 RGRERSRPIA SILEEVKKLS EQGLKEVTLL GQNVNSFRDN SEVQFNSAVP TNLSRGFTTN 250 260 270 280 290 300 YKTKQGGLRF AHLLDQVSRV DPEMRIRFTS PHPKDFPDEV LQLIHERDNI CKQIHLPAQS 310 320 330 340 350 360 GSSRVLEAMR RGYSREAYVE LVHHIRESIP GVSLSSDFIA GFCGETEEDH VQTVSLLREV 370 380 390 400 410 420 QYNMGFLFAY SMRQKTRAYH RLKDDVPEEV KLRRLEELIT IFREEATKAN QTSVGCTQLV 430 440 450 460 470 480 LVEGLSKRSA TDLCGRNDGN LKVIFPDAEM EDVNNPGLRV RAQPGDYVLV KITSASSQTL 490 RGHVLCRTTL RDSSAYC
	Isoform 3 (a) [UniParc]. Checksum: 314E826B35C346EB	FASTA	587	66,146
	10 20 30 40 50 60 MHPLQCVLQV QRSLGWGPLA SVSWLSLRMC RAHSSLSSTM CPSPERQEDG ARKDFSSRLA 70 80 90 100 110 120 AGPTFQHFLK SASAPQEKLS SEVEDPPPYL MMDELLGRQR KVYLETYGCQ MNVNDTEIAW 130 140 150 160 170 180 SILQKSGYLR TSNLQEADVI LLVTCSIREK AEQTIWNRLH QLKALKTRRP RSRVPLRIGI 190 200 210 220 230 240 LGCMAERLKE EILNREKMVD ILAGPDAYRD LPRLLAVAES GQQAANVLLS LDETYADVMP 250 260 270 280 290 300 VQTSASATSA FVSIMRGCDN MCSYCIVPFT RGRERSRPIA SILEEVKKLS EQGLKEVTLL 310 320 330 340 350 360 GQNVNSFRDN SEVQFNSAVP TNLSRGFTTN YKTKQGGLRF AHLLDQVSRV DPEMRIRFTS 370 380 390 400 410 420 PHPKDFPDEV LQLIHERDNI CKQIHLPAQS GSSRVLEAMR RGYSREAYVE LVHHIRESIP 430 440 450 460 470 480 GVSLSSDFIA GFCGETEEDH VQTVSLLREV QYNMGFLFAY SMRQKTRAYH RLKDDVPEEV 490 500 510 520 530 540 KLRRLEELIT IFREEATKAN QTSVGCTQLV LVEGLSKRSA TDLCGRNDGN LKVIFPDAEM 550 560 570 580 EDVNNPGLRV RAQPGDYVLV KITSASSQTL RGHVLCRTTL RDSSAYC
	Isoform 4 [UniParc]. Checksum: 8F0DFB3B71E135BB	FASTA	510	57,413
	10 20 30 40 50 60 MHPLQCVLQV QRSLGWGPLA SVSWLSLRMC RAHSSLSSTM CPSPERQEDG ARKDFSSRLA 70 80 90 100 110 120 AGPTFQHFLK SASAPQEKLS SEVEDPPPYL MMDELLGRQR KVYLETYGCQ MNVNDTEIAW 130 140 150 160 170 180 SILQKSGYLR TSNLQEADVI LLVTCSIREK AEQTIWNRLH QLKALKTRRP RSRVPLRIGI 190 200 210 220 230 240 LGCMAERLKE EILNREKMVD ILAGPDAYRD LPRLLAVAES GQQAANVLLS LDETYADVMP 250 260 270 280 290 300 VQTSASATSA FVSIMRGCDN MCSYCIVPFT RGRERSRPIA SILEEVKKLS EQVLQLIHER 310 320 330 340 350 360 DNICKQIHLP AQSGSSRVLE AMRRGYSREA YVELVHHIRE SIPGVSLSSD FIAGFCGETE 370 380 390 400 410 420 EDHVQTVSLL REVQYNMGFL FAYSMRQKTR AYHRLKDDVP EEVKLRRLEE LITIFREEAT 430 440 450 460 470 480 KANQTSVGCT QLVLVEGLSK RSATDLCGRN DGNLKVIFPD AEMEDVNNPG LRVRAQPGDY 490 500 510 VLVKITSASS QTLRGHVLCR TTLRDSSAYC

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics." Lai C.-H., Chou C.-Y., Ch'ang L.-Y., Liu C.-S., Lin W.-C. Genome Res. 10:703-713(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
[2]	"Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells." Zhang Q.-H., Ye M., Wu X.-Y., Ren S.-X., Zhao M., Zhao C.-J., Fu G., Shen Y., Fan H.-Y., Lu G., Zhong M., Xu X.-R., Han Z.-G., Zhang J.-W., Tao J., Huang Q.-H., Zhou J., Hu G.-X. , Gu J., Chen S.-J., Chen Z. Genome Res. 10:1546-1560(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3). Tissue: Umbilical cord blood.
[3]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 3). Tissue: Retinoblastoma, Stomach and Teratocarcinoma.
[4]	"The DNA sequence and comparative analysis of human chromosome 20." Deloukas P., Matthews L.H., Ashurst J.L., Burton J., Gilbert J.G.R., Jones M., Stavrides G., Almeida J.P., Babbage A.K., Bagguley C.L., Bailey J., Barlow K.F., Bates K.N., Beard L.M., Beare D.M., Beasley O.P., Bird C.P., Blakey S.E. , Bridgeman A.M., Brown A.J., Buck D., Burrill W.D., Butler A.P., Carder C., Carter N.P., Chapman J.C., Clamp M., Clark G., Clark L.N., Clark S.Y., Clee C.M., Clegg S., Cobley V.E., Collier R.E., Connor R.E., Corby N.R., Coulson A., Coville G.J., Deadman R., Dhami P.D., Dunn M., Ellington A.G., Frankland J.A., Fraser A., French L., Garner P., Grafham D.V., Griffiths C., Griffiths M.N.D., Gwilliam R., Hall R.E., Hammond S., Harley J.L., Heath P.D., Ho S., Holden J.L., Howden P.J., Huckle E., Hunt A.R., Hunt S.E., Jekosch K., Johnson C.M., Johnson D., Kay M.P., Kimberley A.M., King A., Knights A., Laird G.K., Lawlor S., Lehvaeslaiho M.H., Leversha M.A., Lloyd C., Lloyd D.M., Lovell J.D., Marsh V.L., Martin S.L., McConnachie L.J., McLay K., McMurray A.A., Milne S.A., Mistry D., Moore M.J.F., Mullikin J.C., Nickerson T., Oliver K., Parker A., Patel R., Pearce T.A.V., Peck A.I., Phillimore B.J.C.T., Prathalingam S.R., Plumb R.W., Ramsay H., Rice C.M., Ross M.T., Scott C.E., Sehra H.K., Shownkeen R., Sims S., Skuce C.D., Smith M.L., Soderlund C., Steward C.A., Sulston J.E., Swann R.M., Sycamore N., Taylor R., Tee L., Thomas D.W., Thorpe A., Tracey A., Tromans A.C., Vaudin M., Wall M., Wallis J.M., Whitehead S.L., Whittaker P., Willey D.L., Williams L., Williams S.A., Wilming L., Wray P.W., Hubbard T., Durbin R.M., Bentley D.R., Beck S., Rogers J. Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[5]	Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[6]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4). Tissue: Duodenum and Lung.
[7]	"Cloning of three novel neuronal Cdk5 activator binding proteins." Ching Y.-P., Qi Z., Wang J.H. Gene 242:285-294(2000) [PubMed] [Europe PMC] [Abstract] Cited for: TISSUE SPECIFICITY.
[8]	"Identification of a neuronal Cdk5 activator-binding protein as Cdk5 inhibitor." Ching Y.-P., Pang A.S.H., Lam W.-H., Qi R.Z., Wang J.H. J. Biol. Chem. 277:15237-15240(2002) [PubMed] [Europe PMC] [Abstract] Cited for: INTERACTION WITH CDK5 AND CDK5R1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF152097 mRNA. Translation: AAD34147.1. Frameshift. AF161516 mRNA. Translation: AAF29131.1. Frameshift. AK023992 mRNA. Translation: BAB14760.1. AK027449 mRNA. Translation: BAB55120.1. Sequence problems. AK292075 mRNA. Translation: BAF84764.1. AL355392 Genomic DNA. Translation: CAI19392.1. AL355392 Genomic DNA. Translation: CAI19393.1. AL355392 Genomic DNA. Translation: CAI19394.1. CH471077 Genomic DNA. Translation: EAW76319.1. CH471077 Genomic DNA. Translation: EAW76322.1. CH471077 Genomic DNA. Translation: EAW76323.1. BC001215 mRNA. Translation: AAH01215.1. BC050706 mRNA. Translation: AAH50706.1.
IPI	IPI00306312. IPI00328276. IPI00328277. IPI00328278.
RefSeq	NP_057166.3. NM_016082.3. NP_057492.2. NM_016408.2.
UniGene	Hs.435952.
3D structure databases
ProteinModelPortal	Q96SZ6.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q96SZ6. 2 interactions.
PTM databases
PhosphoSite	Q96SZ6.
Polymorphism databases
DMDM	32129446.
Proteomic databases
PaxDb	Q96SZ6.
PRIDE	Q96SZ6.
Protocols and materials databases
DNASU	51654.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000339269; ENSP00000341840; ENSG00000101391. ENST00000346416; ENSP00000217372; ENSG00000101391. ENST00000357886; ENSP00000350558; ENSG00000101391. ENST00000452723; ENSP00000408133; ENSG00000101391.
GeneID	51654.
KEGG	hsa:51654.
UCSC	uc002wyy.3. human. uc002wyz.3. human. uc010gek.3. human. uc010gem.3. human.
Organism-specific databases
CTD	51654.
GeneCards	GC20M031946.
HGNC	HGNC:15880. CDK5RAP1.
MIM	608200. gene.
neXtProt	NX_Q96SZ6.
PharmGKB	PA26313.
GenAtlas	Search...
Phylogenomic databases
eggNOG	COG0621.
HOVERGEN	HBG050975.
InParanoid	Q96SZ6.
OMA	GIDRIRY.
PhylomeDB	Q96SZ6.
Gene expression databases
ArrayExpress	Q96SZ6.
Bgee	Q96SZ6.
CleanEx	HS_CDK5RAP1.
Genevestigator	Q96SZ6.
GermOnline	ENSG00000101391. Homo sapiens.
Family and domain databases
Gene3D	3.80.30.20. 1 hit.
InterPro	IPR006638. Elp3/MiaB/NifB. IPR023970. MeThioTfrase/rSAM. IPR005839. Methylthiotransferase. IPR020612. Methylthiotransferase_CS. IPR013848. Methylthiotransferase_N. IPR006463. MiaB_methiolase. IPR007197. rSAM. IPR023404. rSAM_horseshoe. IPR002792. TRAM_dom. [Graphical view]
PANTHER	PTHR11918. PTHR11918. 1 hit.
Pfam	PF04055. Radical_SAM. 1 hit. PF01938. TRAM. 1 hit. PF00919. UPF0004. 1 hit. [Graphical view]
SMART	SM00729. Elp3. 1 hit. [Graphical view]
TIGRFAMs	TIGR01574. miaB-methiolase. 1 hit. TIGR00089. TIGR00089. 1 hit.
PROSITE	PS51449. MTTASE_N. 1 hit. PS01278. MTTASE_RADICAL. 1 hit. PS50926. TRAM. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	CDK5RAP1. human.
GenomeRNAi	51654.
NextBio	55620.
SOURCE	Search...

Entry information

Entry name

CK5P1_HUMAN

Accession

Primary (citable) accession number: Q96SZ6
Secondary accession number(s): A8K7R0 , Q5QP46, Q5QP47, Q5QP48, Q9BVG6, Q9BWZ5, Q9H859, Q9NZZ9, Q9Y3F0

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 16, 2003
Last sequence update:	June 16, 2003
Last modified:	May 1, 2013
This is version 119 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.