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1 to 22 of 22  Show
  1. 1
    "Identification and tissue distribution of the novel human cytochrome P450 2S1 (CYP2S1)."
    Rylander T., Neve E., Ingelman-Sundberg M., Oscarson M.
    Biochem. Biophys. Res. Commun. 281:529-535(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), SUBCELLULAR LOCATION, TISSUE SPECIFICITY.
    Category: Subcellular Location, Expression, Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).
  2. 2
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 1015 other entries.

  3. 3
    "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
    Category: Sequences.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 12923 other entries.

  4. 4
    "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Category: Sequences.
    Tissue: Blood.
    Source: UniProtKB/Swiss-Prot (reviewed).

    This publication is cited by 50494 other entries.

  5. 5
    "Identification of genetic polymorphisms of CYP2S1 in a Finnish Caucasian population."
    Saarikoski S.T., Suitiala T., Holmila R., Impivaara O., Jarvisalo J., Hirvonen A., Husgafvel-Pursiainen K.
    Mutat. Res. 554:267-277(2004) [PubMed] [Europe PMC] [Abstract]
    Annotation: Observational study of genotype prevalence. (HuGE Navigator)Imported.
    Source: GeneRIF:29785.

    This publication is mapped to 1 other entry.

  6. 6
    "A novel promoter element containing multiple overlapping xenobiotic and hypoxia response elements mediates induction of cytochrome P4502S1 by both dioxin and hypoxia."
    Rivera S.P., Wang F., Saarikoski S.T., Taylor R.T., Chapman B., Zhang R., Hankinson O.
    J. Biol. Chem. 282:10881-10893(2007) [PubMed] [Europe PMC] [Abstract]
    Annotation: identify a novel regulatory cassette that mediates changes in Cyp2s1 expressionImported.
    Source: GeneRIF:29785.

    This publication is mapped to 1 other entry.

  7. 7
    "Expression of CYP2S1 in human hepatic stellate cells."
    Marek C.J., Tucker S.J., Koruth M., Wallace K., Wright M.C.
    FEBS Lett. 581:781-786(2007) [PubMed] [Europe PMC] [Abstract]
    Annotation: The presence of a CYP2A-related protein and testosterone metabolism in stellate cell cultures suggest that stellate cells express specific functional isoforms of CYP of which a major form is CYP2S1Imported.
    Source: GeneRIF:29785.

    This publication is mapped to 1 other entry.

  8. 8
    "Three novel single nucleotide polymorphisms (SNPs) of CYP2S1 gene in Japanese individuals."
    Hanzawa Y., Sasaki T., Hiratsuka M., Ishikawa M., Mizugaki M.
    Drug Metab. Pharmacokinet. 22:136-140(2007) [PubMed] [Europe PMC] [Abstract]
    Annotation: Observational study of genotype prevalence. (HuGE Navigator); identified the following three novel single nucleotide polymorphisms (SNPs): 4612G>A (Glu147Glu) in exon 3 5478C>T (Leu230Leu) and 5479T>G (Leu230Arg CYP2S1*5A) in exon 5 in Japanese individualsImported.
    Source: GeneRIF:29785.

    This publication is mapped to 1 other entry.

  9. 9
    "CYP2S1 gene polymorphisms in a Korean population."
    Jang Y.J., Cha E.Y., Kim W.Y., Park S.W., Shon J.H., Lee S.S., Shin J.G.
    Ther Drug Monit 29:292-298(2007) [PubMed] [Europe PMC] [Abstract]
    Annotation: 12 genetic variations which included the two novel nonsynonymous mutations CYP2S1 S61N (0.3%) and CYP2S1 L230R (0.8%) were identified in 50 Korean subjectsImported.
    Source: GeneRIF:29785.

    This publication is mapped to 1 other entry.

  10. 10
    "Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects."
    Saito A., Kawamoto M., Kamatani N.
    J. Hum. Genet. 54:317-323(2009) [PubMed] [Europe PMC] [Abstract]
    Annotation: Observational study of gene-disease association. (HuGE Navigator)Imported.
    Source: GeneRIF:29785.

    This publication is mapped to 923 other entries.

  11. 11
    "Characterization and expression of extrahepatic CYP2S1."
    Deb S., Bandiera S.M.
    Expert Opin Drug Metab Toxicol 5:367-380(2009) [PubMed] [Europe PMC] [Abstract]
    Annotation: Review compares the expression of CYP2S1 mRNA and protein in humans mice and rats and critically examines evidence pertaining to CYP2S1 regulation and its catalytic activity.Imported.
    Source: GeneRIF:29785.

    This publication is mapped to 1 other entry.

  12. 12
    "Functional characterization of human cytochrome P450 2S1 using a synthetic gene-expressed protein in Escherichia coli."
    Bui P.H., Hankinson O.
    Mol. Pharmacol. 76:1031-1043(2009) [PubMed] [Europe PMC] [Abstract]
    Annotation: CYP2S1 contributes to the metabolism of environmental carcinogens via a nicotinamide adenine dinucleotide phosphate (NADPH)- independent activity.Imported.
    Source: GeneRIF:29785.

    This publication is mapped to 1 other entry.

  13. 13
    "Cytochrome P450 2S1 is reduced by NADPH-cytochrome P450 reductase."
    Xiao Y., Shinkyo R., Guengerich F.P.
    Drug Metab. Dispos. 39:944-946(2011) [PubMed] [Europe PMC] [Abstract]
    Annotation: P450 2S1 can be reduced by NADPH-P450 reductase and suggest normal mixed-function oxidase roles of P450 2S1 to be revealed.Imported.
    Source: GeneRIF:29785.

    This publication is mapped to 1 other entry.

  14. 14
    "Next-generation sequencing to generate interactome datasets."
    Yu H., Tardivo L., Tam S., Weiner E., Gebreab F., Fan C., Svrzikapa N., Hirozane-Kishikawa T., Rietman E., Yang X., Sahalie J., Salehi-Ashtiani K., Hao T., Cusick M.E., Hill D.E., Roth F.P., Braun P., Vidal M.
    Nat. Methods 8:478-480(2011) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Source: IntAct:Q96SQ9.

    This publication is mapped to 794 other entries.

  15. 15
    "Characterization of a human keratinocyte HaCaT cell line model to study the regulation of CYP2S1."
    McNeilly A.D., Woods J.A., Ibbotson S.H., Wolf C.R., Smith G.
    Drug Metab. Dispos. 40:283-289(2012) [PubMed] [Europe PMC] [Abstract]
    Annotation: Data suggest that CYP2S1 is induced in a keratinocyte cell line by exposure to all-trans retinoic acid and ultraviolet B radiation.Imported.
    Source: GeneRIF:29785.

    This publication is mapped to 1 other entry.

  16. 16
    "[Polymorphic markers of the CYP1B1 (4326C > G), CYP2F1 (c.14_15insC), CYP2J2 (-76G > T), and CYP2S1 (13106C > T and 13255A > G) genes and genetic predisposition to chronic respiratory diseases induced by smoking and occupational factors]."
    Akhmadishina L.A., Korytina G.F., Victorova T.V.
    Genetika 47:1402-1410(2011) [PubMed] [Europe PMC] [Abstract]
    Annotation: No association has been found between the CYP2J2 (rs890293 -76G > T) or CYP2S1 (rs34971233 13106C > T P466L and rs338583 13255A > G) gene polymorphisms and respiratory diseases.Imported.
    Source: GeneRIF:29785.

    This publication is mapped to 30 other entries.

  17. 17
    "Cytochrome P450 2S1 depletion enhances cell proliferation and migration in bronchial epithelial cells, in part, through modulation of prostaglandin E(2) synthesis."
    Madanayake T.W., Fidler T.P., Fresquez T.M., Bajaj N., Rowland A.M.
    Drug Metab. Dispos. 40:2119-2125(2012) [PubMed] [Europe PMC] [Abstract]
    Annotation: The reduction in CYP2S1 expression doubled intracellular PGE(2) levels.Imported.
    Source: GeneRIF:29785.

    This publication is mapped to 1 other entry.

  18. 18
    "Cytochrome P4502S1: a novel monocyte/macrophage fatty acid epoxygenase in human atherosclerotic plaques."
    Fromel T., Kohlstedt K., Popp R., Yin X., Awwad K., Barbosa-Sicard E., Thomas A.C., Lieberz R., Mayr M., Fleming I.
    Basic Res. Cardiol. 108:319-319(2013) [PubMed] [Europe PMC] [Abstract]
    Annotation: found that CYP inhibition and siRNA-mediated downregulation of CYP2S1 increased macrophage phagocytosisImported.
    Source: GeneRIF:29785.

    This publication is mapped to 1 other entry.

  19. 19
    "Biotransformation of (+)-fenchone by Salmonella typhimurium OY1002/2A6 expressing human CYP2A6 and NADPH-P450 reductase."
    Nakahashi H., Yagi N., Miyazawa M.
    J Oleo Sci 62:293-296(2013) [PubMed] [Europe PMC] [Abstract]
    Annotation: NADPH-P450 reductaseImported.
    Source: GeneRIF:29785.

    This publication is mapped to 1 other entry.

  20. 20
    "Reduction of aromatic and heterocyclic aromatic N-hydroxylamines by human cytochrome P450 2S1."
    Wang K., Guengerich F.P.
    Chem. Res. Toxicol. 26:993-1004(2013) [PubMed] [Europe PMC] [Abstract]
    Annotation: The P450 2S1 may be involved in the reductive detoxication of several of the activated products of carcinogenic aromatic amines and heterocyclic aromatic amines.Imported.
    Source: GeneRIF:29785.

    This publication is mapped to 1 other entry.

  21. 21
    Category: Interaction.
    Source: IntAct:Q96SQ9.

    This publication is mapped to 4123 other entries.

  22. 22
    "CYP2S1 depletion enhances colorectal cell proliferation is associated with PGE2-mediated activation of beta-catenin signaling."
    Yang C., Li C., Li M., Tong X., Hu X., Yang X., Yan X., He L., Wan C.
    Exp. Cell Res. 331:377-386(2015) [PubMed] [Europe PMC] [Abstract]
    Annotation: CYP2S1 regulates colorectal cancer growth through associated with prostaglandin E2-mediated activation of beta-catenin signaling.Imported.
    Source: GeneRIF:29785.

    This publication is mapped to 1 other entry.

1 to 22 of 22  Show