Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q96SI9

- STRBP_HUMAN

UniProt

Q96SI9 - STRBP_HUMAN

Protein

Spermatid perinuclear RNA-binding protein

Gene

STRBP

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 118 (01 Oct 2014)
      Sequence version 1 (01 Dec 2001)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Involved in spermatogenesis and sperm function. Plays a role in regulation of cell growth. Binds to double-stranded DNA and RNA. Binds most efficiently to poly(I:C) RNA than to poly(dI:dC) DNA. Binds also to single-stranded poly(G) RNA. Binds non-specifically to the mRNA PRM1 3'-UTR and adenovirus VA RNA By similarity.By similarity

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB-KW
    2. double-stranded RNA binding Source: Ensembl
    3. poly(A) RNA binding Source: UniProtKB
    4. single-stranded RNA binding Source: Ensembl

    GO - Biological processi

    1. cellular component movement Source: Ensembl
    2. mechanosensory behavior Source: Ensembl
    3. multicellular organismal development Source: UniProtKB-KW
    4. spermatid development Source: Ensembl

    Keywords - Molecular functioni

    Developmental protein

    Keywords - Biological processi

    Differentiation, Spermatogenesis

    Keywords - Ligandi

    DNA-binding, RNA-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Spermatid perinuclear RNA-binding protein
    Gene namesi
    Name:STRBP
    Synonyms:SPNR
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 9

    Organism-specific databases

    HGNCiHGNC:16462. STRBP.

    Subcellular locationi

    Cytoplasm By similarity
    Note: Microtubule-associated that localizes to the manchette in developing spermatids.By similarity

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell
    2. microtubule cytoskeleton Source: Ensembl
    3. nucleus Source: LIFEdb

    Keywords - Cellular componenti

    Cytoplasm

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA38145.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 672672Spermatid perinuclear RNA-binding proteinPRO_0000274917Add
    BLAST

    Proteomic databases

    MaxQBiQ96SI9.
    PaxDbiQ96SI9.
    PRIDEiQ96SI9.

    PTM databases

    PhosphoSiteiQ96SI9.

    Expressioni

    Gene expression databases

    ArrayExpressiQ96SI9.
    BgeeiQ96SI9.
    CleanExiHS_STRBP.
    GenevestigatoriQ96SI9.

    Organism-specific databases

    HPAiHPA020651.

    Interactioni

    Subunit structurei

    Interacts with EIF2AK2. Associates with microtubules; it is unsure whether such interaction is direct or indirect.By similarity

    Protein-protein interaction databases

    BioGridi120623. 22 interactions.
    IntActiQ96SI9. 6 interactions.
    MINTiMINT-1434039.
    STRINGi9606.ENSP00000321347.

    Structurei

    Secondary structure

    1
    672
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Beta strandi385 – 3873
    Helixi390 – 3989
    Beta strandi405 – 4117
    Beta strandi413 – 4153
    Beta strandi417 – 4248
    Beta strandi427 – 4359
    Helixi436 – 45116

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    2DMYNMR-A378-461[»]
    ProteinModelPortaliQ96SI9.
    SMRiQ96SI9. Positions 5-332, 378-576.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiQ96SI9.

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini5 – 363359DZFAdd
    BLAST
    Domaini387 – 45367DRBM 1PROSITE-ProRule annotationAdd
    BLAST
    Domaini510 – 57667DRBM 2PROSITE-ProRule annotationAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi584 – 5874Poly-Lys

    Sequence similaritiesi

    Contains 2 DRBM (double-stranded RNA-binding) domains.PROSITE-ProRule annotation
    Contains 1 DZF domain.Curated

    Keywords - Domaini

    Repeat

    Phylogenomic databases

    eggNOGiNOG269067.
    HOVERGENiHBG069915.
    InParanoidiQ96SI9.
    KOiK13200.
    OMAiYQVEQCV.
    OrthoDBiEOG72ZCDC.
    PhylomeDBiQ96SI9.
    TreeFamiTF320194.

    Family and domain databases

    Gene3Di3.30.160.20. 2 hits.
    InterProiIPR014720. dsRNA-bd_dom.
    IPR006561. DZF.
    [Graphical view]
    PfamiPF00035. dsrm. 2 hits.
    PF07528. DZF. 1 hit.
    [Graphical view]
    SMARTiSM00358. DSRM. 2 hits.
    SM00572. DZF. 1 hit.
    [Graphical view]
    PROSITEiPS50137. DS_RBD. 2 hits.
    [Graphical view]

    Sequences (2)i

    Sequence statusi: Complete.

    This entry describes 2 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q96SI9-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MRSIRSFAND DRHVMVKHST IYPSPEELEA VQNMVSTVEC ALKHVSDWLD    50
    ETNKGTKTEG ETEVKKDEAG ENYSKDQGGR TLCGVMRIGL VAKGLLIKDD 100
    MDLELVLMCK DKPTETLLNT VKDNLPIQIQ KLTEEKYQVE QCVNEASIII 150
    RNTKEPTLTL KVILTSPLIR DELEKKDGEN VSMKDPPDLL DRQKCLNALA 200
    SLRHAKWFQA RANGLKSCVI VLRILRDLCN RVPTWAPLKG WPLELICEKS 250
    IGTCNRPLGA GEALRRVMEC LASGILLPGG PGLHDPCERD PTDALSYMTI 300
    QQKEDITHSA QHALRLSAFG QIYKVLEMDP LPSSKPFQKY SWSVTDKEGA 350
    GSSALKRPFE DGLGDDKDPN KKMKRNLRKI LDSKAIDLMN ALMRLNQIRP 400
    GLQYKLLSQS GPVHAPVFTM SVDVDGTTYE ASGPSKKTAK LHVAVKVLQA 450
    MGYPTGFDAD IECMSSDEKS DNESKNETVS SNSSNNTGNS TTETSSTLEV 500
    RTQGPILTAS GKNPVMELNE KRRGLKYELI SETGGSHDKR FVMEVEVDGQ 550
    KFRGAGPNKK VAKASAALAA LEKLFSGPNA ANNKKKKIIP QAKGVVNTAV 600
    SAAVQAVRGR GRGTLTRGAF VGATAAPGYI APGYGTPYGY STAAPAYGLP 650
    KRMVLLPVMK FPTYPVPHYS FF 672
    Length:672
    Mass (Da):73,653
    Last modified:December 1, 2001 - v1
    Checksum:i26465F4D3A429FBC
    GO
    Isoform 2 (identifier: Q96SI9-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-14: Missing.

    Show »
    Length:658
    Mass (Da):71,967
    Checksum:i131F93237EEF70B1
    GO

    Sequence cautioni

    The sequence AAI08732.1 differs from that shown. Reason: Contaminating sequence. Potential poly-A sequence.
    The sequence BAA92120.1 differs from that shown. Reason: Erroneous initiation.
    The sequence BAB14873.1 differs from that shown. Reason: Erroneous initiation.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti173 – 1753LEK → IGRR in AAK20832. 1 PublicationCurated
    Sequence conflicti196 – 1961L → P in BAA92120. (PubMed:14702039)Curated

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti280 – 2801G → R in a breast cancer sample; somatic mutation. 1 Publication
    VAR_035662

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei1 – 1414Missing in isoform 2. 1 PublicationVSP_022937Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF333337 mRNA. Translation: AAK20832.1.
    AL136866 mRNA. Translation: CAB66800.1.
    AK002169 mRNA. Translation: BAA92120.1. Different initiation.
    AK024285 mRNA. Translation: BAB14873.1. Different initiation.
    AK027890 mRNA. Translation: BAB55434.1.
    AL365338 Genomic DNA. Translation: CAH70299.1.
    AL365338 Genomic DNA. Translation: CAH70300.1.
    BC002693 mRNA. Translation: AAH02693.2.
    BC017732 mRNA. Translation: AAH17732.1.
    BC108731 mRNA. Translation: AAI08732.1. Sequence problems.
    CCDSiCCDS55337.1. [Q96SI9-2]
    CCDS6851.1. [Q96SI9-1]
    RefSeqiNP_001164608.1. NM_001171137.1. [Q96SI9-2]
    NP_060857.2. NM_018387.4. [Q96SI9-1]
    XP_005252140.1. XM_005252083.2. [Q96SI9-1]
    UniGeneiHs.287659.
    Hs.694157.

    Genome annotation databases

    EnsembliENST00000348403; ENSP00000321347; ENSG00000165209. [Q96SI9-1]
    ENST00000360998; ENSP00000354271; ENSG00000165209. [Q96SI9-2]
    ENST00000447404; ENSP00000415968; ENSG00000165209. [Q96SI9-1]
    GeneIDi55342.
    KEGGihsa:55342.
    UCSCiuc004bns.3. human. [Q96SI9-1]

    Polymorphism databases

    DMDMi74752134.

    Keywords - Coding sequence diversityi

    Alternative splicing, Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF333337 mRNA. Translation: AAK20832.1 .
    AL136866 mRNA. Translation: CAB66800.1 .
    AK002169 mRNA. Translation: BAA92120.1 . Different initiation.
    AK024285 mRNA. Translation: BAB14873.1 . Different initiation.
    AK027890 mRNA. Translation: BAB55434.1 .
    AL365338 Genomic DNA. Translation: CAH70299.1 .
    AL365338 Genomic DNA. Translation: CAH70300.1 .
    BC002693 mRNA. Translation: AAH02693.2 .
    BC017732 mRNA. Translation: AAH17732.1 .
    BC108731 mRNA. Translation: AAI08732.1 . Sequence problems.
    CCDSi CCDS55337.1. [Q96SI9-2 ]
    CCDS6851.1. [Q96SI9-1 ]
    RefSeqi NP_001164608.1. NM_001171137.1. [Q96SI9-2 ]
    NP_060857.2. NM_018387.4. [Q96SI9-1 ]
    XP_005252140.1. XM_005252083.2. [Q96SI9-1 ]
    UniGenei Hs.287659.
    Hs.694157.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    2DMY NMR - A 378-461 [» ]
    ProteinModelPortali Q96SI9.
    SMRi Q96SI9. Positions 5-332, 378-576.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 120623. 22 interactions.
    IntActi Q96SI9. 6 interactions.
    MINTi MINT-1434039.
    STRINGi 9606.ENSP00000321347.

    PTM databases

    PhosphoSitei Q96SI9.

    Polymorphism databases

    DMDMi 74752134.

    Proteomic databases

    MaxQBi Q96SI9.
    PaxDbi Q96SI9.
    PRIDEi Q96SI9.

    Protocols and materials databases

    DNASUi 55342.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000348403 ; ENSP00000321347 ; ENSG00000165209 . [Q96SI9-1 ]
    ENST00000360998 ; ENSP00000354271 ; ENSG00000165209 . [Q96SI9-2 ]
    ENST00000447404 ; ENSP00000415968 ; ENSG00000165209 . [Q96SI9-1 ]
    GeneIDi 55342.
    KEGGi hsa:55342.
    UCSCi uc004bns.3. human. [Q96SI9-1 ]

    Organism-specific databases

    CTDi 55342.
    GeneCardsi GC09M125871.
    HGNCi HGNC:16462. STRBP.
    HPAi HPA020651.
    MIMi 611138. gene.
    neXtProti NX_Q96SI9.
    PharmGKBi PA38145.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG269067.
    HOVERGENi HBG069915.
    InParanoidi Q96SI9.
    KOi K13200.
    OMAi YQVEQCV.
    OrthoDBi EOG72ZCDC.
    PhylomeDBi Q96SI9.
    TreeFami TF320194.

    Miscellaneous databases

    ChiTaRSi STRBP. human.
    EvolutionaryTracei Q96SI9.
    GeneWikii STRBP.
    GenomeRNAii 55342.
    NextBioi 59667.
    PROi Q96SI9.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q96SI9.
    Bgeei Q96SI9.
    CleanExi HS_STRBP.
    Genevestigatori Q96SI9.

    Family and domain databases

    Gene3Di 3.30.160.20. 2 hits.
    InterProi IPR014720. dsRNA-bd_dom.
    IPR006561. DZF.
    [Graphical view ]
    Pfami PF00035. dsrm. 2 hits.
    PF07528. DZF. 1 hit.
    [Graphical view ]
    SMARTi SM00358. DSRM. 2 hits.
    SM00572. DZF. 1 hit.
    [Graphical view ]
    PROSITEi PS50137. DS_RBD. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Sha J.H., Zhou Z.M., Li J.M.
      Submitted (JAN-2001) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
      Tissue: Testis.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
      Tissue: Testis.
    3. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
      Tissue: Placenta and Retinoblastoma.
    4. "DNA sequence and analysis of human chromosome 9."
      Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L., Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R., Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S., Bagguley C.L.
      , Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beasley H., Beasley O., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burford D., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Chen Y., Clarke G., Clark S.Y., Clee C.M., Clegg S., Collier R.E., Corby N., Crosier M., Cummings A.T., Davies J., Dhami P., Dunn M., Dutta I., Dyer L.W., Earthrowl M.E., Faulkner L., Fleming C.J., Frankish A., Frankland J.A., French L., Fricker D.G., Garner P., Garnett J., Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S., Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E., Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D., Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E., Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K., Kimberley A.M., King A., Knights A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M., Lovell J., Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S., McLay K.E., McMurray A., Milne S., Nickerson T., Nisbett J., Nordsiek G., Pearce A.V., Peck A.I., Porter K.M., Pandian R., Pelan S., Phillimore B., Povey S., Ramsey Y., Rand V., Scharfe M., Sehra H.K., Shownkeen R., Sims S.K., Skuce C.D., Smith M., Steward C.A., Swarbreck D., Sycamore N., Tester J., Thorpe A., Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Williams S.A., Wilming L., Wray P.W., Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R.M., Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S., Rogers J., Dunham I.
      Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
      Tissue: Leiomyosarcoma, Retinoblastoma and Uterus.
    6. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
      Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    7. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    8. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
      Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    9. "Solution structure of DSRM domain in spermatid perinuclear RNA-binding protein."
      RIKEN structural genomics initiative (RSGI)
      Submitted (OCT-2006) to the PDB data bank
      Cited for: STRUCTURE BY NMR OF 378-461.
    10. Cited for: VARIANT [LARGE SCALE ANALYSIS] ARG-280.

    Entry informationi

    Entry nameiSTRBP_HUMAN
    AccessioniPrimary (citable) accession number: Q96SI9
    Secondary accession number(s): Q32NB9
    , Q9BUE1, Q9BXG4, Q9H0B4, Q9H7V1, Q9NUK4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 6, 2007
    Last sequence update: December 1, 2001
    Last modified: October 1, 2014
    This is version 118 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Reference proteome

    Documents

    1. Human chromosome 9
      Human chromosome 9: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    4. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    5. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    6. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3