Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Transcription factor AP-2 alpha (Activating enhancer binding protein 2 alpha), isoform CRA_c

Gene

TFAP2A

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Transcription factor AP-2 alpha (Activating enhancer binding protein 2 alpha), isoform CRA_cImported
Submitted name:
Transcription factor AP-2-alphaImported
Gene namesi
Name:TFAP2AImported
ORF Names:hCG_37170Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 6

Organism-specific databases

HGNCiHGNC:11742. TFAP2A.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000137203.

PTM / Processingi

Proteomic databases

EPDiQ96SH1.
MaxQBiQ96SH1.
PRIDEiQ96SH1.

Expressioni

Gene expression databases

BgeeiENSG00000137203.
ExpressionAtlasiQ96SH1. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000368924.

Structurei

3D structure databases

ProteinModelPortaliQ96SH1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini213 – 407TF_AP-2InterPro annotationAdd BLAST195

Phylogenomic databases

eggNOGiKOG3811. Eukaryota.
ENOG410XR9E. LUCA.
GeneTreeiENSGT00550000074577.
HOGENOMiHOG000231737.
OMAiQHRGLPH.
OrthoDBiEOG091G0PR6.
PhylomeDBiQ96SH1.

Family and domain databases

InterProiIPR004979. TF_AP2.
IPR008121. TF_AP2_alpha_N.
IPR013854. TF_AP2_C.
[Graphical view]
PANTHERiPTHR10812. PTHR10812. 1 hit.
PfamiPF03299. TF_AP-2. 1 hit.
[Graphical view]
PRINTSiPR01749. AP2ATNSCPFCT.
PR01748. AP2TNSCPFCT.

Sequencei

Sequence statusi: Complete.

Q96SH1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKMLWKLTDN IKYEDCEDRH DGTSNGTARL PQLGTVGQSP YTSAPPLSHT
60 70 80 90 100
PNADFQPPYF PPPYQPIYPQ SQDPYSHVND PYSLNPLHAQ PQPQHPGWPG
110 120 130 140 150
QRQSQESGLL HTHRGLPHQL SGLDPRRDYR RHEDLLHGPH ALSSGLGDLS
160 170 180 190 200
IHSLPHAIEE VPHVEDPGIN IPDQTVIKKG PVSLSKSNSN AVSAIPINKD
210 220 230 240 250
NLFGGVVNPN EVFCSVPGRL SLLSSTSKYK VTVAEVQRRL SPPECLNASL
260 270 280 290 300
LGGVLRRAKS KNGGRSLREK LDKIGLNLPA GRRKAANVTL LTSLVEGEAV
310 320 330 340 350
HLARDFGYVC ETEFPAKAVA EFLNRQHSDP NEQVTRKNML LATKQICKEF
360 370 380 390 400
TDLLAQDRSP LGNSRPNPIL EPGIQSCLTH FNLISHGFGS PAVCAAVTAL
410 420 430
QNYLTEALKA MDKMYLSNNP NSHTDNNAKS SDKEEKHRK
Length:439
Mass (Da):48,321
Last modified:December 1, 2001 - v1
Checksum:iBE1212805EB2E89F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL138885 Genomic DNA. No translation available.
CH471087 Genomic DNA. Translation: EAW55250.1.
UniGeneiHs.519880.

Genome annotation databases

EnsembliENST00000379613; ENSP00000368933; ENSG00000137203.
UCSCiuc003myr.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL138885 Genomic DNA. No translation available.
CH471087 Genomic DNA. Translation: EAW55250.1.
UniGeneiHs.519880.

3D structure databases

ProteinModelPortaliQ96SH1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000368924.

Proteomic databases

EPDiQ96SH1.
MaxQBiQ96SH1.
PRIDEiQ96SH1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000379613; ENSP00000368933; ENSG00000137203.
UCSCiuc003myr.4. human.

Organism-specific databases

HGNCiHGNC:11742. TFAP2A.
OpenTargetsiENSG00000137203.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3811. Eukaryota.
ENOG410XR9E. LUCA.
GeneTreeiENSGT00550000074577.
HOGENOMiHOG000231737.
OMAiQHRGLPH.
OrthoDBiEOG091G0PR6.
PhylomeDBiQ96SH1.

Miscellaneous databases

ChiTaRSiTFAP2A. human.

Gene expression databases

BgeeiENSG00000137203.
ExpressionAtlasiQ96SH1. baseline and differential.

Family and domain databases

InterProiIPR004979. TF_AP2.
IPR008121. TF_AP2_alpha_N.
IPR013854. TF_AP2_C.
[Graphical view]
PANTHERiPTHR10812. PTHR10812. 1 hit.
PfamiPF03299. TF_AP-2. 1 hit.
[Graphical view]
PRINTSiPR01749. AP2ATNSCPFCT.
PR01748. AP2TNSCPFCT.
ProtoNetiSearch...

Entry informationi

Entry nameiQ96SH1_HUMAN
AccessioniPrimary (citable) accession number: Q96SH1
Entry historyi
Integrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: November 2, 2016
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.