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Protein
Submitted name:

Transcription factor AP-2 alpha (Activating enhancer binding protein 2 alpha), isoform CRA_c

Gene

TFAP2A

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Transcription factor AP-2 alpha (Activating enhancer binding protein 2 alpha), isoform CRA_cImported
Submitted name:
Transcription factor AP-2-alphaImported
Gene namesi
Name:TFAP2AImported
ORF Names:hCG_37170Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 6

Organism-specific databases

EuPathDBiHostDB:ENSG00000137203.10
HGNCiHGNC:11742 TFAP2A

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000137203

Expressioni

Gene expression databases

BgeeiENSG00000137203

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini213 – 407TF_AP-2InterPro annotationAdd BLAST195

Phylogenomic databases

eggNOGiKOG3811 Eukaryota
ENOG410XR9E LUCA
GeneTreeiENSGT00550000074577
HOGENOMiHOG000231737
OMAiEYVNRQH
OrthoDBiEOG091G0PR6

Family and domain databases

InterProiView protein in InterPro
IPR004979 TF_AP2
IPR008121 TF_AP2_alpha_N
IPR013854 TF_AP2_C
PANTHERiPTHR10812 PTHR10812, 1 hit
PTHR10812:SF8 PTHR10812:SF8, 1 hit
PfamiView protein in Pfam
PF03299 TF_AP-2, 1 hit
PRINTSiPR01749 AP2ATNSCPFCT
PR01748 AP2TNSCPFCT

Sequencei

Sequence statusi: Complete.

Q96SH1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKMLWKLTDN IKYEDCEDRH DGTSNGTARL PQLGTVGQSP YTSAPPLSHT
60 70 80 90 100
PNADFQPPYF PPPYQPIYPQ SQDPYSHVND PYSLNPLHAQ PQPQHPGWPG
110 120 130 140 150
QRQSQESGLL HTHRGLPHQL SGLDPRRDYR RHEDLLHGPH ALSSGLGDLS
160 170 180 190 200
IHSLPHAIEE VPHVEDPGIN IPDQTVIKKG PVSLSKSNSN AVSAIPINKD
210 220 230 240 250
NLFGGVVNPN EVFCSVPGRL SLLSSTSKYK VTVAEVQRRL SPPECLNASL
260 270 280 290 300
LGGVLRRAKS KNGGRSLREK LDKIGLNLPA GRRKAANVTL LTSLVEGEAV
310 320 330 340 350
HLARDFGYVC ETEFPAKAVA EFLNRQHSDP NEQVTRKNML LATKQICKEF
360 370 380 390 400
TDLLAQDRSP LGNSRPNPIL EPGIQSCLTH FNLISHGFGS PAVCAAVTAL
410 420 430
QNYLTEALKA MDKMYLSNNP NSHTDNNAKS SDKEEKHRK
Length:439
Mass (Da):48,321
Last modified:December 1, 2001 - v1
Checksum:iBE1212805EB2E89F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL138885 Genomic DNA No translation available.
CH471087 Genomic DNA Translation: EAW55250.1
UniGeneiHs.519880

Genome annotation databases

EnsembliENST00000379613; ENSP00000368933; ENSG00000137203
UCSCiuc003myr.4 human

Similar proteinsi

Entry informationi

Entry nameiQ96SH1_HUMAN
AccessioniPrimary (citable) accession number: Q96SH1
Entry historyiIntegrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: May 23, 2018
This is version 106 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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