UniProtKB - Q96S82 (UBL7_HUMAN)
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Protein
Ubiquitin-like protein 7
Gene
UBL7
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Recommended name: Ubiquitin-like protein 7Alternative name(s): Bone marrow stromal cell ubiquitin-like protein Short name: BMSC-UbP Ubiquitin-like protein SB132 |
Gene namesi | Name:UBL7 Synonyms:BMSCUBP ORF Names:SB132 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
EuPathDBi | HostDB:ENSG00000138629.15. |
HGNCi | HGNC:28221. UBL7. |
MIMi | 609748. gene. |
neXtProti | NX_Q96S82. |
Pathology & Biotechi
Organism-specific databases
DisGeNETi | 84993. |
OpenTargetsi | ENSG00000138629. |
PharmGKBi | PA142670645. |
Polymorphism and mutation databases
BioMutai | UBL7. |
DMDMi | 48474599. |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000211021 | 1 – 380 | Ubiquitin-like protein 7Add BLAST | 380 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 230 | PhosphoserineCombined sources | 1 |
Keywords - PTMi
PhosphoproteinProteomic databases
EPDi | Q96S82. |
MaxQBi | Q96S82. |
PaxDbi | Q96S82. |
PeptideAtlasi | Q96S82. |
PRIDEi | Q96S82. |
PTM databases
iPTMneti | Q96S82. |
PhosphoSitePlusi | Q96S82. |
Expressioni
Tissue specificityi
Ubiquitous. Highly expressed in heart, skeletal muscle, testis, thyroid and adrenal gland.1 Publication
Inductioni
Down-regulated by phorbol myristate acetate (PMA) in bone marrow stroma cells.
Gene expression databases
Bgeei | ENSG00000138629. |
CleanExi | HS_UBL7. |
ExpressionAtlasi | Q96S82. baseline and differential. |
Genevisiblei | Q96S82. HS. |
Organism-specific databases
HPAi | HPA040423. HPA041897. |
Interactioni
Subunit structurei
Binds ubiquitin.1 Publication
Binary interactionsi
Protein-protein interaction databases
BioGridi | 124418. 47 interactors. |
IntActi | Q96S82. 12 interactors. |
STRINGi | 9606.ENSP00000354883. |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more detailsFeature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Helixi | 339 – 346 | Combined sources | 8 | |
Turni | 347 – 349 | Combined sources | 3 | |
Helixi | 353 – 363 | Combined sources | 11 | |
Helixi | 367 – 376 | Combined sources | 10 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
2CWB | NMR | - | A | 336-380 | [»] | |
2DEN | NMR | - | A | 336-380 | [»] | |
ProteinModelPortali | Q96S82. | |||||
SMRi | Q96S82. | |||||
ModBasei | Search... | |||||
MobiDBi | Search... |
Miscellaneous databases
EvolutionaryTracei | Q96S82. |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 18 – 98 | Ubiquitin-likePROSITE-ProRule annotationAdd BLAST | 81 | |
Domaini | 333 – 377 | UBAPROSITE-ProRule annotationAdd BLAST | 45 |
Phylogenomic databases
eggNOGi | ENOG410ISS5. Eukaryota. ENOG410YUJQ. LUCA. |
GeneTreei | ENSGT00390000015967. |
HOVERGENi | HBG054051. |
InParanoidi | Q96S82. |
OMAi | HAINLLM. |
OrthoDBi | EOG091G0II5. |
PhylomeDBi | Q96S82. |
TreeFami | TF327176. |
Family and domain databases
InterProi | View protein in InterPro IPR015940. UBA. IPR009060. UBA-like_sf. IPR015496. Ubiquilin. IPR029071. Ubiquitin-like_domsf. IPR000626. Ubiquitin_dom. |
PANTHERi | PTHR10677. PTHR10677. 1 hit. |
Pfami | View protein in Pfam PF00627. UBA. 1 hit. PF00240. ubiquitin. 1 hit. |
SMARTi | View protein in SMART SM00165. UBA. 1 hit. SM00213. UBQ. 1 hit. |
SUPFAMi | SSF46934. SSF46934. 1 hit. SSF54236. SSF54236. 1 hit. |
PROSITEi | View protein in PROSITE PS50030. UBA. 1 hit. PS50053. UBIQUITIN_2. 1 hit. |
i Sequence
Sequence statusi: Complete.
Q96S82-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSLSDWHLAV KLADQPLTPK SILRLPETEL GEYSLGGYSI SFLKQLIAGK
60 70 80 90 100
LQESVPDPEL IDLIYCGRKL KDDQTLDFYG IQPGSTVHVL RKSWPEPDQK
110 120 130 140 150
PEPVDKVAAM REFRVLHTAL HSSSSYREAV FKMLSNKESL DQIIVATPGL
160 170 180 190 200
SSDPIALGVL QDKDLFSVFA DPNMLDTLVP AHPALVNAIV LVLHSVAGSA
210 220 230 240 250
PMPGTDSSSR SMPSSSYRDM PGGFLFEGLS DDEDDFHPNT RSTPSSSTPS
260 270 280 290 300
SRPASLGYSG AAGPRPITQS ELATALALAS TPESSSHTPT PGTQGHSSGT
310 320 330 340 350
SPMSSGVQSG TPITNDLFSQ ALQHALQASG QPSLQSQWQP QLQQLRDMGI
360 370 380
QDDELSLRAL QATGGDIQAA LELIFAGGAP
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 262 | A → V in AAK67643 (PubMed:12644319).Curated | 1 | |
Sequence conflicti | 272 | L → R in AAK67643 (PubMed:12644319).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AY037166 mRNA. Translation: AAK67643.1. CH471136 Genomic DNA. Translation: EAW99332.1. CH471136 Genomic DNA. Translation: EAW99335.1. CH471136 Genomic DNA. Translation: EAW99339.1. BC007913 mRNA. Translation: AAH07913.1. BC030055 mRNA. Translation: AAH30055.1. BC033919 mRNA. Translation: AAH33919.1. |
CCDSi | CCDS10263.1. |
RefSeqi | NP_001273668.1. NM_001286739.1. NP_001273669.1. NM_001286740.1. NP_001273670.1. NM_001286741.1. NP_001273671.1. NM_001286742.1. NP_116296.1. NM_032907.4. NP_957717.1. NM_201265.1. |
UniGenei | Hs.334713. |
Genome annotation databases
Ensembli | ENST00000361351; ENSP00000354883; ENSG00000138629. ENST00000395081; ENSP00000378518; ENSG00000138629. ENST00000564488; ENSP00000454828; ENSG00000138629. ENST00000565335; ENSP00000457708; ENSG00000138629. ENST00000567435; ENSP00000457703; ENSG00000138629. |
GeneIDi | 84993. |
KEGGi | hsa:84993. |
UCSCi | uc002axw.3. human. |
Similar proteinsi
Entry informationi
Entry namei | UBL7_HUMAN | |
Accessioni | Q96S82Primary (citable) accession number: Q96S82 Secondary accession number(s): D3DW57, Q96I03 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | March 29, 2004 |
Last sequence update: | March 29, 2004 | |
Last modified: | March 28, 2018 | |
This is version 143 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |