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Q96R84 (OR1F2_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 88. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Web links·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Putative olfactory receptor 1F2
Alternative name(s):
OLFmf2
Gene names
Name:OR1F2P
Synonyms:OR1F2
OrganismHomo sapiens (Human) [Reference proteome]
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length312 AA.
Sequence statusComplete.
Protein existenceUncertain

General annotation (Comments)

Function

Odorant receptor Potential.

Subcellular location

Cell membrane; Multi-pass membrane protein.

Sequence similarities

Belongs to the G-protein coupled receptor 1 family.

Caution

Could be the product of a pseudogene.

Sequence caution

The sequence AJ003145 differs from that shown. Reason: Frameshift at position 1.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 312312Putative olfactory receptor 1F2
PRO_0000150432

Regions

Topological domain1 – 2525Extracellular Potential
Transmembrane26 – 4924Helical; Name=1; Potential
Topological domain50 – 578Cytoplasmic Potential
Transmembrane58 – 7821Helical; Name=2; Potential
Topological domain79 – 9921Extracellular Potential
Transmembrane100 – 11920Helical; Name=3; Potential
Topological domain120 – 13819Cytoplasmic Potential
Transmembrane139 – 15719Helical; Name=4; Potential
Topological domain158 – 19538Extracellular Potential
Transmembrane196 – 21823Helical; Name=5; Potential
Topological domain219 – 23517Cytoplasmic Potential
Transmembrane236 – 25823Helical; Name=6; Potential
Topological domain259 – 27113Extracellular Potential
Transmembrane272 – 29120Helical; Name=7; Potential
Topological domain292 – 31221Cytoplasmic Potential

Amino acid modifications

Disulfide bond96 ↔ 188 By similarity

Experimental info

Sequence conflict1361I → T in AAK95043. Ref.2

Sequences

Sequence LengthMass (Da)Tools
Q96R84 [UniParc].

Last modified October 10, 2003. Version 2.
Checksum: 96B49B6DDBB11285

FASTA31234,944
        10         20         30         40         50         60 
MERDKPVSVS EFLLLGLSRQ PQQQHLLFVF FLSMYLATVL GNLLIILAIS IDSRLHTPMY 

        70         80         90        100        110        120 
FFLSNMSFVD NCFSTTVPKM LANHILRTQT ISFSGCLMQM YFISELADMD NFLLAVMAYD 

       130        140        150        160        170        180 
RFVAVCRPLH YTAKMIHQLC ALLVTGSWVV ANSNALLHTL LMARLSFCAD NTIPHIFCDV 

       190        200        210        220        230        240 
TPLLKLSCSD THLSEVMILT EAALVTITPF LCLLASYMHI TCVVLRVPST KGRWKAFSTC 

       250        260        270        280        290        300 
GSHLAVVLLF YGTIMSPYFR TSSSHSAQRD IAAAVRFTVV TPVMNPLIYS LRNKDIKGAL 

       310 
VKVVAVKFFS VQ 

« Hide

References

[1]"A transcriptional map of the FMF region."
Bernot A., Heilig R., Clepet C., Smaoui N., Da Silva C., Petit J.-L., Devaud C., Chiannilkulchai N., Fizames C., Samson D., Cruaud C., Caloustian C., Gyapay G., Delpech M., Weissenbach J.
Genomics 50:147-160(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]"DEFOG: a practical scheme for deciphering families of genes."
Fuchs T., Malecova B., Linhart C., Sharan R., Khen M., Herwig R., Shmulevich D., Elkon R., Steinfath M., O'Brien J.K., Radelof U., Lehrach H., Lancet D., Shamir R.
Genomics 80:295-302(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 68-283.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ003145 mRNA. No translation available.
AF399558 Genomic DNA. Translation: AAK95043.1.
UniGeneHs.651203.

3D structure databases

ProteinModelPortalQ96R84.
SMRQ96R84. Positions 36-157.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

GPCRDBSearch...

Proteomic databases

PRIDEQ96R84.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

UCSCuc010uwv.2. human.

Organism-specific databases

GeneCardsGC16P003267.
HGNCHGNC:8196. OR1F2P.
neXtProtNX_Q96R84.
PharmGKBPA32075.
GenAtlasSearch...

Phylogenomic databases

HOVERGENHBG017625.
PhylomeDBQ96R84.

Enzyme and pathway databases

ReactomeREACT_111102. Signal Transduction.

Gene expression databases

GenevestigatorQ96R84.

Family and domain databases

Gene3D1.20.1070.10. 1 hit.
InterProIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR000725. Olfact_rcpt.
[Graphical view]
PRINTSPR00237. GPCRRHODOPSN.
PR00245. OLFACTORYR.
PROSITEPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

PROQ96R84.

Entry information

Entry nameOR1F2_HUMAN
AccessionPrimary (citable) accession number: Q96R84
Entry history
Integrated into UniProtKB/Swiss-Prot: October 10, 2003
Last sequence update: October 10, 2003
Last modified: June 11, 2014
This is version 88 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

SIMILARITY comments

Index of protein domains and families

Human chromosome 16

Human chromosome 16: entries, gene names and cross-references to MIM

7-transmembrane G-linked receptors

List of 7-transmembrane G-linked receptor entries