Q96QA6 (YPEL2_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein yippee-like 2

Gene names

Name:	YPEL2
ORF Names:	FKSG4

Organism

Homo sapiens (Human)

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	119 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Subcellular location	Nucleus › nucleolus Ref.1.
Tissue specificity	Widely expressed. Detected in fetal and adult kidney, heart, liver, lung and skeletal muscle. Ref.1
Sequence similarities	Belongs to the yippee family.

Ontologies

Keywords
Cellular component	Nucleus
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular component	nucleolus Inferred from electronic annotation. Source: UniProtKB-SubCell
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 119	119	Protein yippee-like 2		PRO_0000212385

Sequences

	Sequence		Length	Mass (Da)
	Q96QA6 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: 5904018C67E1A2D2	FASTA	119	13,577
	10 20 30 40 50 60 MVKMTRSKTF QAYLPSCHRT YSCIHCRAHL ANHDELISKS FQGSQGRAYL FNSVVNVGCG 70 80 90 100 110 PAEERVLLTG LHAVADIYCE NCKTTLGWKY EHAFESSQKY KEGKYIIELA HMIKDNGWD

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Identification and characterization of a novel gene family YPEL in a wide spectrum of eukaryotic species." Hosono K., Sasaki T., Minoshima S., Shimizu N. Gene 340:31-43(2004) [PubMed: 15556292] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], SUBCELLULAR LOCATION, TISSUE SPECIFICITY.
[2]	"Cloning and characterization of FKSG4, a novel gene related to DiGeorge syndrome." Wang Y.-G. Submitted (SEP-2000) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[3]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Lung.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AB098736 Genomic DNA. Translation: BAD51377.1. AF305195 mRNA. Translation: AAL09354.1. BC127924 mRNA. Translation: AAI27925.1. BC132884 mRNA. Translation: AAI32885.1. BC132886 mRNA. Translation: AAI32887.1.
IPI	IPI00397639.
RefSeq	NP_001005404.1. NM_001005404.3.
UniGene	Hs.463613.
3D structure databases
ProteinModelPortal	Q96QA6.
ModBase	Search...
Protein-protein interaction databases
STRING	Q96QA6.
PTM databases
PhosphoSite	Q96QA6.
Polymorphism databases
DMDM	27805781.
Proteomic databases
PRIDE	Q96QA6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000312655; ENSP00000312272; ENSG00000175155.
GeneID	388403.
KEGG	hsa:388403.
UCSC	uc002ixm.1. human.
Organism-specific databases
CTD	388403.
GeneCards	GC17P057409.
H-InvDB	HIX0021796.
HGNC	HGNC:18326. YPEL2.
HPA	HPA030501.
MIM	609723. gene.
neXtProt	NX_Q96QA6.
PharmGKB	PA134978522.
GenAtlas	Search...
Phylogenomic databases
eggNOG	prNOG04871.
GeneTree	ENSGT00390000008364.
HOGENOM	HBG524054.
HOVERGEN	HBG054215.
InParanoid	Q96QA6.
OMA	ERAYENS.
OrthoDB	EOG4HQDKR.
PhylomeDB	Q96QA6.
Gene expression databases
ArrayExpress	Q96QA6.
Bgee	Q96QA6.
CleanEx	HS_YPEL2.
Genevestigator	Q96QA6.
GermOnline	ENSG00000175155. Homo sapiens.
Family and domain databases
InterPro	IPR004910. Yippee. [Graphical view]
Pfam	PF03226. Yippee. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	102030.
SOURCE	Search...

Entry information

Entry name

YPEL2_HUMAN

Accession

Primary (citable) accession number: Q96QA6
Secondary accession number(s): A0PK16 , A2RUG4, Q65ZA0, Q8N3W2

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 17, 2003
Last sequence update:	December 1, 2001
Last modified:	January 25, 2012
This is version 65 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.