Q96Q91 (B3A4_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Anion exchange protein 4
Short name=AE 4
Short name=Anion exchanger 4

Alternative name(s):
Sodium bicarbonate cotransporter 5
Solute carrier family 4 member 9

Gene names

Name:	SLC4A9
Synonyms:	AE4, SBC5

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	983 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	Probable apical anion exchanger of the kidney cortex By similarity.
Subcellular location	Membrane; Multi-pass membrane protein.
Tissue specificity	Kidney specific. Ref.2 Ref.7
Sequence similarities	Belongs to the anion exchanger (TC 2.A.31) family. [View classification]
Sequence caution	The sequence AAK28832.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Biological process	Anion exchange Antiport Ion transport Transport
Cellular component	Membrane
Coding sequence diversity	Alternative splicing
Domain	Transmembrane Transmembrane helix
PTM	Glycoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	bicarbonate transport Traceable author statement. Source: Reactome transmembrane transport Traceable author statement. Source: Reactome
Cellular_component	apical part of cell Inferred from electronic annotation. Source: Compara integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Traceable author statement. Source: Reactome
Molecular_function	inorganic anion exchanger activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Alternative products

This entry describes 4 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q96Q91-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q96Q91-2)

The sequence of this isoform differs from the canonical sequence as follows:
     77-100: Missing.
     384-394: Missing.
     592-594: Missing.

Isoform 3 (identifier: Q96Q91-3)

The sequence of this isoform differs from the canonical sequence as follows:
     77-100: Missing.

Isoform 4 (identifier: Q96Q91-4)

The sequence of this isoform differs from the canonical sequence as follows:
     77-100: Missing.
     595-657: Missing.

Note: No experimental confirmation available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 983	983	Anion exchange protein 4		PRO_0000079223
Regions
	Topological domain	1 – 414	414	Cytoplasmic Potential
	Transmembrane	415 – 435	21	Helical; Potential
	Transmembrane	443 – 463	21	Helical; Potential
	Transmembrane	465 – 485	21	Helical; Potential
	Transmembrane	500 – 520	21	Helical; Potential
	Transmembrane	530 – 550	21	Helical; Potential
	Topological domain	551 – 623	73	Extracellular Potential
	Transmembrane	624 – 644	21	Helical; Potential
	Transmembrane	665 – 685	21	Helical; Potential
	Topological domain	686 – 711	26	Cytoplasmic Potential
	Transmembrane	712 – 732	21	Helical; Potential
	Transmembrane	758 – 778	21	Helical; Potential
	Transmembrane	815 – 835	21	Helical; Potential
	Transmembrane	837 – 857	21	Helical; Potential
	Transmembrane	899 – 919	21	Helical; Potential
	Region	415 – 983	569	Membrane (anion exchange)
Amino acid modifications
	Glycosylation	576	1	N-linked (GlcNAc...) Potential
	Glycosylation	600	1	N-linked (GlcNAc...) Potential
Natural variations
	Alternative sequence	77 – 100	24	Missing in isoform 2, isoform 3 and isoform 4.		VSP_007085
	Alternative sequence	384 – 394	11	Missing in isoform 2.		VSP_007086
	Alternative sequence	592 – 594	3	Missing in isoform 2.		VSP_007087
	Alternative sequence	595 – 657	63	Missing in isoform 4.		VSP_044785
Experimental info
	Sequence conflict	23	1	G → W in AAI36263. Ref.5
	Sequence conflict	23	1	G → W in AAI43603. Ref.5
	Sequence conflict	101	1	R → T in AAK69625. Ref.4
	Sequence conflict	453	1	V → M in AAK16733. Ref.1
	Sequence conflict	795	1	R → K in AAK16733. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified March 28, 2003. Version 2. Checksum: E2AEB04C9D27E6BC	FASTA	983	108,248
	10 20 30 40 50 60 MEMKLPGQEG FEASSAPRNI PSGELDSNPD PGTGPSPDGP SDTESKELGV PKDPLLFIQL 70 80 90 100 110 120 NELLGWPQAL EWRETGSSSA SLLLDMGEMP SITLSTHLHH RWVLFEEKLE VAAGRWSAPH 130 140 150 160 170 180 VPTLALPSLQ KLRSLLAEGL VLLDCPAQSL LELVEQVTRV ESLSPELRGQ LQALLLQRPQ 190 200 210 220 230 240 HYNQTTGTRP CWGSTHPRKA SDNEEAPLRE QCQNPLRQKL PPGAEAGTVL AGELGFLAQP 250 260 270 280 290 300 LGAFVRLRNP VVLGSLTEVS LPSRFFCLLL GPCMLGKGYH EMGRAAAVLL SDPQFQWSVR 310 320 330 340 350 360 RASNLHDLLA ALDAFLEEVT VLPPGRWDPT ARIPPPKCLP SQHKRLPSQQ REIRGPAVPR 370 380 390 400 410 420 LTSAEDRHRH GPHAHSPELQ RTGRLFGGLI QDVRRKVPWY PSDFLDALHL QCFSAVLYIY 430 440 450 460 470 480 LATVTNAITF GGLLGDATDG AQGVLESFLG TAVAGAAFCL MAGQPLTILS STGPVLVFER 490 500 510 520 530 540 LLFSFSRDYS LDYLPFRLWV GIWVATFCLV LVATEASVLV RYFTRFTEEG FCALISLIFI 550 560 570 580 590 600 YDAVGKMLNL THTYPIQKPG SSAYGCLCQY PGPGGNESQW IRTRPKDRDD IVSMDLGLIN 610 620 630 640 650 660 ASLLPPPECT RQGGHPRGPG CHTVPDIAFF SLLLFLTSFF FAMALKCVKT SRFFPSVVRK 670 680 690 700 710 720 GLSDFSSVLA ILLGCGLDAF LGLATPKLMV PREFKPTLPG RGWLVSPFGA NPWWWSVAAA 730 740 750 760 770 780 LPALLLSILI FMDQQITAVI LNRMEYRLQK GAGFHLDLFC VAVLMLLTSA LGLPWYVSAT 790 800 810 820 830 840 VISLAHMDSL RRESRACAPG ERPNFLGIRE QRLTGLVVFI LTGASIFLAP VLKFIPMPVL 850 860 870 880 890 900 YGIFLYMGVA ALSSIQFTNR VKLLLMPAKH QPDLLLLRHV PLTRVHLFTA IQLACLGLLW 910 920 930 940 950 960 IIKSTPAAII FPLMLLGLVG VRKALERVFS PQELLWLDEL MPEEERSIPE KGLEPEHSFS 970 980 GSDSEDSELM YQPKAPEINI SVN
	Isoform 2 [UniParc]. Checksum: 4221B3EF5309C1C0	FASTA	945	104,128
	10 20 30 40 50 60 MEMKLPGQEG FEASSAPRNI PSGELDSNPD PGTGPSPDGP SDTESKELGV PKDPLLFIQL 70 80 90 100 110 120 NELLGWPQAL EWRETGRWVL FEEKLEVAAG RWSAPHVPTL ALPSLQKLRS LLAEGLVLLD 130 140 150 160 170 180 CPAQSLLELV EQVTRVESLS PELRGQLQAL LLQRPQHYNQ TTGTRPCWGS THPRKASDNE 190 200 210 220 230 240 EAPLREQCQN PLRQKLPPGA EAGTVLAGEL GFLAQPLGAF VRLRNPVVLG SLTEVSLPSR 250 260 270 280 290 300 FFCLLLGPCM LGKGYHEMGR AAAVLLSDPQ FQWSVRRASN LHDLLAALDA FLEEVTVLPP 310 320 330 340 350 360 GRWDPTARIP PPKCLPSQHK RLPSQQREIR GPAVPRLTSA EDRHRHGPHA HSPELQRTGR 370 380 390 400 410 420 KVPWYPSDFL DALHLQCFSA VLYIYLATVT NAITFGGLLG DATDGAQGVL ESFLGTAVAG 430 440 450 460 470 480 AAFCLMAGQP LTILSSTGPV LVFERLLFSF SRDYSLDYLP FRLWVGIWVA TFCLVLVATE 490 500 510 520 530 540 ASVLVRYFTR FTEEGFCALI SLIFIYDAVG KMLNLTHTYP IQKPGSSAYG CLCQYPGPGG 550 560 570 580 590 600 NESQWIRTRP KDRDDIDLGL INASLLPPPE CTRQGGHPRG PGCHTVPDIA FFSLLLFLTS 610 620 630 640 650 660 FFFAMALKCV KTSRFFPSVV RKGLSDFSSV LAILLGCGLD AFLGLATPKL MVPREFKPTL 670 680 690 700 710 720 PGRGWLVSPF GANPWWWSVA AALPALLLSI LIFMDQQITA VILNRMEYRL QKGAGFHLDL 730 740 750 760 770 780 FCVAVLMLLT SALGLPWYVS ATVISLAHMD SLRRESRACA PGERPNFLGI REQRLTGLVV 790 800 810 820 830 840 FILTGASIFL APVLKFIPMP VLYGIFLYMG VAALSSIQFT NRVKLLLMPA KHQPDLLLLR 850 860 870 880 890 900 HVPLTRVHLF TAIQLACLGL LWIIKSTPAA IIFPLMLLGL VGVRKALERV FSPQELLWLD 910 920 930 940 ELMPEEERSI PEKGLEPEHS FSGSDSEDSE LMYQPKAPEI NISVN
	Isoform 3 [UniParc]. Checksum: 2B190D6A5D2E346C	FASTA	959	105,701
	10 20 30 40 50 60 MEMKLPGQEG FEASSAPRNI PSGELDSNPD PGTGPSPDGP SDTESKELGV PKDPLLFIQL 70 80 90 100 110 120 NELLGWPQAL EWRETGRWVL FEEKLEVAAG RWSAPHVPTL ALPSLQKLRS LLAEGLVLLD 130 140 150 160 170 180 CPAQSLLELV EQVTRVESLS PELRGQLQAL LLQRPQHYNQ TTGTRPCWGS THPRKASDNE 190 200 210 220 230 240 EAPLREQCQN PLRQKLPPGA EAGTVLAGEL GFLAQPLGAF VRLRNPVVLG SLTEVSLPSR 250 260 270 280 290 300 FFCLLLGPCM LGKGYHEMGR AAAVLLSDPQ FQWSVRRASN LHDLLAALDA FLEEVTVLPP 310 320 330 340 350 360 GRWDPTARIP PPKCLPSQHK RLPSQQREIR GPAVPRLTSA EDRHRHGPHA HSPELQRTGR 370 380 390 400 410 420 LFGGLIQDVR RKVPWYPSDF LDALHLQCFS AVLYIYLATV TNAITFGGLL GDATDGAQGV 430 440 450 460 470 480 LESFLGTAVA GAAFCLMAGQ PLTILSSTGP VLVFERLLFS FSRDYSLDYL PFRLWVGIWV 490 500 510 520 530 540 ATFCLVLVAT EASVLVRYFT RFTEEGFCAL ISLIFIYDAV GKMLNLTHTY PIQKPGSSAY 550 560 570 580 590 600 GCLCQYPGPG GNESQWIRTR PKDRDDIVSM DLGLINASLL PPPECTRQGG HPRGPGCHTV 610 620 630 640 650 660 PDIAFFSLLL FLTSFFFAMA LKCVKTSRFF PSVVRKGLSD FSSVLAILLG CGLDAFLGLA 670 680 690 700 710 720 TPKLMVPREF KPTLPGRGWL VSPFGANPWW WSVAAALPAL LLSILIFMDQ QITAVILNRM 730 740 750 760 770 780 EYRLQKGAGF HLDLFCVAVL MLLTSALGLP WYVSATVISL AHMDSLRRES RACAPGERPN 790 800 810 820 830 840 FLGIREQRLT GLVVFILTGA SIFLAPVLKF IPMPVLYGIF LYMGVAALSS IQFTNRVKLL 850 860 870 880 890 900 LMPAKHQPDL LLLRHVPLTR VHLFTAIQLA CLGLLWIIKS TPAAIIFPLM LLGLVGVRKA 910 920 930 940 950 LERVFSPQEL LWLDELMPEE ERSIPEKGLE PEHSFSGSDS EDSELMYQPK APEINISVN
	Isoform 4 [UniParc]. Checksum: B6E908619855FCCC	FASTA	896	98,851
	10 20 30 40 50 60 MEMKLPGQEG FEASSAPRNI PSGELDSNPD PGTGPSPDGP SDTESKELGV PKDPLLFIQL 70 80 90 100 110 120 NELLGWPQAL EWRETGRWVL FEEKLEVAAG RWSAPHVPTL ALPSLQKLRS LLAEGLVLLD 130 140 150 160 170 180 CPAQSLLELV EQVTRVESLS PELRGQLQAL LLQRPQHYNQ TTGTRPCWGS THPRKASDNE 190 200 210 220 230 240 EAPLREQCQN PLRQKLPPGA EAGTVLAGEL GFLAQPLGAF VRLRNPVVLG SLTEVSLPSR 250 260 270 280 290 300 FFCLLLGPCM LGKGYHEMGR AAAVLLSDPQ FQWSVRRASN LHDLLAALDA FLEEVTVLPP 310 320 330 340 350 360 GRWDPTARIP PPKCLPSQHK RLPSQQREIR GPAVPRLTSA EDRHRHGPHA HSPELQRTGR 370 380 390 400 410 420 LFGGLIQDVR RKVPWYPSDF LDALHLQCFS AVLYIYLATV TNAITFGGLL GDATDGAQGV 430 440 450 460 470 480 LESFLGTAVA GAAFCLMAGQ PLTILSSTGP VLVFERLLFS FSRDYSLDYL PFRLWVGIWV 490 500 510 520 530 540 ATFCLVLVAT EASVLVRYFT RFTEEGFCAL ISLIFIYDAV GKMLNLTHTY PIQKPGSSAY 550 560 570 580 590 600 GCLCQYPGPG GNESQWIRTR PKDRDDIVSM VRKGLSDFSS VLAILLGCGL DAFLGLATPK 610 620 630 640 650 660 LMVPREFKPT LPGRGWLVSP FGANPWWWSV AAALPALLLS ILIFMDQQIT AVILNRMEYR 670 680 690 700 710 720 LQKGAGFHLD LFCVAVLMLL TSALGLPWYV SATVISLAHM DSLRRESRAC APGERPNFLG 730 740 750 760 770 780 IREQRLTGLV VFILTGASIF LAPVLKFIPM PVLYGIFLYM GVAALSSIQF TNRVKLLLMP 790 800 810 820 830 840 AKHQPDLLLL RHVPLTRVHL FTAIQLACLG LLWIIKSTPA AIIFPLMLLG LVGVRKALER 850 860 870 880 890 VFSPQELLWL DELMPEEERS IPEKGLEPEH SFSGSDSEDS ELMYQPKAPE INISVN

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Human BTR1, a new bicarbonate transporter superfamily member and human AE4 from kidney." Parker M.D., Ourmozdi E.P., Tanner M.J.A. Biochem. Biophys. Res. Commun. 282:1103-1109(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2). Tissue: Kidney and Testis.
[2]	"A novel sodium bicarbonate cotransporter-like gene in an ancient duplicated region: SLC4A9 at 5q31." Lipovich L., Lynch E.D., Lee M.K., King M.-C. Genome Biol. 2:RESEARCH0011.1-RESEARCH0011.13(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), TISSUE SPECIFICITY. Tissue: Kidney.
[3]	"The DNA sequence and comparative analysis of human chromosome 5." Schmutz J., Martin J., Terry A., Couronne O., Grimwood J., Lowry S., Gordon L.A., Scott D., Xie G., Huang W., Hellsten U., Tran-Gyamfi M., She X., Prabhakar S., Aerts A., Altherr M., Bajorek E., Black S. , Branscomb E., Caoile C., Challacombe J.F., Chan Y.M., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Glavina T., Gomez M., Gonzales E., Goodstein D., Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Lopez F., Lou Y., Martinez D., Medina C., Morgan J., Nandkeshwar R., Noonan J.P., Pitluck S., Pollard M., Predki P., Priest J., Ramirez L., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wheeler J., Wu K., Yang J., Dickson M., Cheng J.-F., Eichler E.E., Olsen A., Pennacchio L.A., Rokhsar D.S., Richardson P., Lucas S.M., Myers R.M., Rubin E.M. Nature 431:268-274(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[4]	"Cloning and characterization of human AE4." Karet F.E. Submitted (DEC-2000) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3).
[5]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4). Tissue: Lung, Placenta and Testis.
[6]	Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[7]	"Molecular cloning of human sodium bicarbonate cotransporter 5." Ishibashi K. Submitted (SEP-1999) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 3-983 (ISOFORM 3), TISSUE SPECIFICITY. Tissue: Testis.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AF336237 mRNA. Translation: AAK16733.1. AF313465 mRNA. Translation: AAK28832.1. Different initiation. AF332961 mRNA. Translation: AAK69625.1. AC008438 Genomic DNA. No translation available. CH471062 Genomic DNA. Translation: EAW62062.1. CH471062 Genomic DNA. Translation: EAW62063.1. CH471062 Genomic DNA. Translation: EAW62064.1. CH471062 Genomic DNA. Translation: EAW62066.1. CH471062 Genomic DNA. Translation: EAW62067.1. CH471062 Genomic DNA. Translation: EAW62068.1. BC136262 mRNA. Translation: AAI36263.1. BC143602 mRNA. Translation: AAI43603.1. AB032762 mRNA. Translation: BAA93010.1.
IPI	IPI00000234. IPI00216571. IPI00292101. IPI00922025.
RefSeq	NP_001245355.1. NM_001258426.1. NP_001245356.1. NM_001258427.1. NP_001245357.1. NM_001258428.1. NP_113655.2. NM_031467.2.
UniGene	Hs.550313.
3D structure databases
ProteinModelPortal	Q96Q91.
ModBase	Search...
Protein-protein interaction databases
STRING	9606.ENSP00000387708.
PTM databases
PhosphoSite	Q96Q91.
Polymorphism databases
DMDM	29427950.
Proteomic databases
PaxDb	Q96Q91.
PRIDE	Q96Q91.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000230993; ENSP00000230993; ENSG00000113073. ENST00000432095; ENSP00000410056; ENSG00000113073. ENST00000506545; ENSP00000422855; ENSG00000113073. ENST00000506757; ENSP00000424424; ENSG00000113073. ENST00000507527; ENSP00000427661; ENSG00000113073.
GeneID	83697.
KEGG	hsa:83697.
UCSC	uc003lfj.2. human. uc003lfk.2. human. uc003lfm.2. human.
Organism-specific databases
CTD	83697.
GeneCards	GC05P139719.
H-InvDB	HIX0031939.
HGNC	HGNC:11035. SLC4A9.
HPA	HPA051307.
MIM	610207. gene.
neXtProt	NX_Q96Q91.
PharmGKB	PA35901.
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG301727.
HOVERGEN	HBG004326.
InParanoid	Q96Q91.
KO	K13860.
OMA	QELLWLD.
PhylomeDB	Q96Q91.
Enzyme and pathway databases
Reactome	REACT_15518. Transmembrane transport of small molecules.
Gene expression databases
ArrayExpress	Q96Q91.
Bgee	Q96Q91.
CleanEx	HS_SLC4A9.
Genevestigator	Q96Q91.
GermOnline	ENSG00000113073. Homo sapiens.
Family and domain databases
Gene3D	3.40.1100.10. 1 hit.
InterPro	IPR013769. Band3_cytoplasmic_dom. IPR011531. HCO3_transpt_C. IPR003020. HCO3_transpt_euk. IPR003024. Na/HCO3_transpt. IPR016152. PTrfase/Anion_transptr. [Graphical view]
PANTHER	PTHR11453. PTHR11453. 1 hit.
Pfam	PF07565. Band_3_cyto. 2 hits. PF00955. HCO3_cotransp. 1 hit. [Graphical view]
PRINTS	PR01231. HCO3TRNSPORT. PR01232. NAHCO3TRSPRT.
SUPFAM	SSF55804. PTrfase/Anion_transptr. 1 hit.
TIGRFAMs	TIGR00834. ae. 1 hit.
ProtoNet	Search...
Other
GenomeRNAi	83697.
NextBio	72674.
SOURCE	Search...

Entry information

Entry name

B3A4_HUMAN

Accession

Primary (citable) accession number: Q96Q91
Secondary accession number(s): B7ZL63 , D3DQD4, D3DQD5, D3DQD6, E9PDK1, Q96RM5, Q9BXF2, Q9BXN3

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 28, 2003
Last sequence update:	March 28, 2003
Last modified:	May 1, 2013
This is version 101 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.