Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q96NS1 (YPEL4_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 72. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Protein yippee-like 4
Gene names
Name:YPEL4
OrganismHomo sapiens (Human)
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length127 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subcellular location

Nucleus › nucleolus Ref.1.

Tissue specificity

Widely expressed. Detected adult brain, lung, colon, small intestine and ovary, and in fetal brain, lung, liver and spleen. Ref.1

Sequence similarities

Belongs to the yippee family.

Ontologies

Keywords
   Cellular componentNucleus
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular componentnucleolus

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 127127Protein yippee-like 4
PRO_0000212392

Sequences

Sequence LengthMass (Da)Tools
Q96NS1 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: BF9894D7D03883B3

FASTA12714,301
        10         20         30         40         50         60 
MPSCDPGPGP ACLPTKTFRS YLPRCHRTYS CVHCRAHLAK HDELISKSFQ GSHGRAYLFN 

        70         80         90        100        110        120 
SVVNVGCGPA EQRLLLTGLH SVADIFCESC KTTLGWKYEQ AFETSQKYKE GKYIIEMSHM 


VKDNGWD

« Hide

References

« Hide 'large scale' references
[1]"Identification and characterization of a novel gene family YPEL in a wide spectrum of eukaryotic species."
Hosono K., Sasaki T., Minoshima S., Shimizu N.
Gene 340:31-43(2004) [PubMed: 15556292] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], SUBCELLULAR LOCATION, TISSUE SPECIFICITY.
[2]"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. expand/collapse author list , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
Nat. Genet. 36:40-45(2004) [PubMed: 14702039] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Cerebellum.
[3]Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. expand/collapse author list , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C.
Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[4]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Brain.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AB098738 Genomic DNA. Translation: BAD51379.1.
AK054775 mRNA. Translation: BAB70805.1.
AK124577 mRNA. Translation: BAG54054.1.
CH471076 Genomic DNA. Translation: EAW73765.1.
BC104781 mRNA. Translation: AAI04782.1.
BC112119 mRNA. Translation: AAI12120.1.
IPIIPI00043857.
RefSeqNP_659445.1. NM_145008.2.
UniGeneHs.135978.

3D structure databases

ProteinModelPortalQ96NS1.
ModBaseSearch...

PTM databases

PhosphoSiteQ96NS1.

Polymorphism databases

DMDM27805780.

Proteomic databases

PRIDEQ96NS1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000300022; ENSP00000300022; ENSG00000166793.
GeneID219539.
KEGGhsa:219539.
UCSCuc001nkv.2. human.

Organism-specific databases

CTD219539.
GeneCardsGC11M057412.
H-InvDBHIX0009640.
HGNCHGNC:18328. YPEL4.
MIM609725. gene.
neXtProtNX_Q96NS1.
PharmGKBPA134991609.
GenAtlasSearch...

Phylogenomic databases

eggNOGprNOG08585.
GeneTreeENSGT00390000008364.
HOGENOMHBG524054.
HOVERGENHBG054215.
InParanoidQ96NS1.
OMACKTHLAT.
OrthoDBEOG479F8C.
PhylomeDBQ96NS1.

Gene expression databases

ArrayExpressQ96NS1.
BgeeQ96NS1.
CleanExHS_YPEL4.
GenevestigatorQ96NS1.
GermOnlineENSG00000166793. Homo sapiens.

Family and domain databases

InterProIPR004910. Yippee.
[Graphical view]
PfamPF03226. Yippee. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio90681.
SOURCESearch...

Entry information

Entry nameYPEL4_HUMAN
AccessionPrimary (citable) accession number: Q96NS1
Secondary accession number(s): B3KW92, Q2M3U7, Q65Z98
Entry history
Integrated into UniProtKB/Swiss-Prot: January 17, 2003
Last sequence update: December 1, 2001
Last modified: January 25, 2012
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Relevant documents

Human chromosome 11

Human chromosome 11: entries, gene names and cross-references to MIM

MIM cross-references

Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents