KLHL32

Functionⁱ

GO - Biological processⁱ

fertilization Source: GO_Central
male gonad development Source: GO_Central
protein ubiquitination Source: GOC
spermatid development Source: GO_Central

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Kelch-like protein 32 Alternative name(s): BTB and kelch domain-containing protein 5
Gene namesⁱ	Name:KLHL32 Synonyms:BKLHD5, KIAA1900
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 6

Organism-specific databases

Human Gene Nomenclature Database More...HGNCⁱ	HGNC:21221. KLHL32.

HGNCⁱ

HGNC:21221. KLHL32.

Subcellular locationⁱ

GO - Cellular componentⁱ

Cul3-RING ubiquitin ligase complex Source: GO_Central
cytoplasm Source: GO_Central

Complete GO annotation...

Pathology & Biotechⁱ

Organism-specific databases

DisGeNET More...DisGeNETⁱ	114792.
Open Targets More...OpenTargetsⁱ	ENSG00000186231.
PharmGKBⁱ	PA162393552.

Polymorphism and mutation databases

BioMutaⁱ	KLHL32.
DMDMⁱ	116241269.

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000119083	1 – 620	Kelch-like protein 32Add BLAST		620

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q96NJ5.
PaxDbⁱ	Q96NJ5.
PeptideAtlas More...PeptideAtlasⁱ	Q96NJ5.
PRIDEⁱ	Q96NJ5.

PTM databases

iPTMnetⁱ	Q96NJ5.
PhosphoSitePlusⁱ	Q96NJ5.

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000186231.
CleanExⁱ	HS_KLHL32.
ExpressionAtlasⁱ	Q96NJ5. baseline and differential.
Genevisibleⁱ	Q96NJ5. HS.

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA039150.

HPAⁱ

HPA039150.

Interactionⁱ

Protein-protein interaction databases

BioGridⁱ	125354. 10 interactors.
IntActⁱ	Q96NJ5. 2 interactors.
STRINGⁱ	9606.ENSP00000358265.

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q96NJ5.
SMRⁱ	Q96NJ5.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Domainⁱ	42 – 109	BTBPROSITE-ProRule annotationAdd BLAST	68
Repeatⁱ	290 – 346	Kelch 1Add BLAST	57
Repeatⁱ	347 – 398	Kelch 2Add BLAST	52
Repeatⁱ	399 – 446	Kelch 3Add BLAST	48
Repeatⁱ	447 – 494	Kelch 4Add BLAST	48
Repeatⁱ	496 – 547	Kelch 5Add BLAST	52
Repeatⁱ	549 – 599	Kelch 6Add BLAST	51

Keywords - Domainⁱ

Kelch repeat, Repeat

Phylogenomic databases

eggNOGⁱ	KOG1072. Eukaryota. ENOG4110X8D. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000118825.
HOGENOMⁱ	HOG000231583.
HOVERGENⁱ	HBG107125.
InParanoidⁱ	Q96NJ5.
KEGG Orthology (KO) More...KOⁱ	K10468.
OMAⁱ	QIWQLAV.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G035Z.
PhylomeDBⁱ	Q96NJ5.
TreeFamⁱ	TF328485.

Family and domain databases

Gene3Dⁱ	2.120.10.80. 2 hits.
InterProⁱ	View protein in InterPro IPR011705. BACK. IPR017096. BTB-kelch_protein. IPR000210. BTB/POZ_dom. IPR015915. Kelch-typ_b-propeller. IPR006652. Kelch_1. IPR030570. KLHL32. IPR011333. SKP1/BTB/POZ.
PANTHERⁱ	PTHR24412:SF319. PTHR24412:SF319. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF07707. BACK. 1 hit. PF00651. BTB. 1 hit. PF01344. Kelch_1. 3 hits.
PIRSFⁱ	PIRSF037037. Kelch-like_protein_gigaxonin. 1 hit.
SMARTⁱ	View protein in SMART SM00875. BACK. 1 hit. SM00225. BTB. 1 hit. SM00612. Kelch. 5 hits.
SUPFAMⁱ	SSF54695. SSF54695. 1 hit.
PROSITEⁱ	View protein in PROSITE PS50097. BTB. 1 hit.

Sequences (3)ⁱ

Sequence statusⁱ: Complete.

This entry describes 3 isoformsⁱ produced by alternative splicing. Align Add to basket Added to basket

Isoform 1 (identifier: Q96NJ5-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

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        10         20         30         40         50
MPSERCLSIQ EMLTGQRLCH SESHNDSVLA ALNQQRSDGI LCDITLIAEE 
        60         70         80         90        100
QKFHAHKAVL AACSDYFRAM FSLCMVESGA DEVNLHGVTS LGLKQALEFA 
       110        120        130        140        150
YTGQILLEPG VIQDVLAAGS HLQLLELLNL CSHYLIQELN SFNYLDLYRL 
       160        170        180        190        200
ADLFNLTLLE KAVIDFLVKH LSELLKSRPE EVLTLPYCLL QEVLKSDRLT 
       210        220        230        240        250
SLSEEQIWQL AVRWLEHNCH YQYMDELLQY IRFGLMDVDT LHTVALSHPL 
       260        270        280        290        300
VQASETATAL VNEALEYHQS IYAQPVWQTR RTKPRFQSDT LYIIGGKKRE 
       310        320        330        340        350
VCKVKELRYF NPVDQENALI AAIANWSELA PMPVGRSHHC VAVMGDFLFV 
       360        370        380        390        400
AGGEVEHASG RTCAVRTACR YDPRSNSWAE IAPMKNCREH FVLGAMEEYL 
       410        420        430        440        450
YAVGGRNELR QVLPTVERYC PKKNKWTFVQ SFDRSLSCHA GYVADGLLWI 
       460        470        480        490        500
SGGVTNTAQY QNRLMVYEPN QNKWISRSPM LQRRVYHSMA AVQRKLYVLG 
       510        520        530        540        550
GNDLDYNNDR ILVRHIDSYN IDTDQWTRCN FNLLTGQNES GVAVHNGRIY 
       560        570        580        590        600
LVGGYSIWTN EPLACIQVLD VSREGKEEVF YGPTLPFASN GIAACFLPAP 
       610        620
YFTCPNLQTL QVPHHRIGTI

Length:620

Mass (Da):70,362

Last modified:October 17, 2006 - v2

Checksum:ⁱAABDC5F667854931

GO

Isoform 2 (identifier: Q96NJ5-2) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
69-104: Missing.

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        10         20         30         40         50
MPSERCLSIQ EMLTGQRLCH SESHNDSVLA ALNQQRSDGI LCDITLIAEE 
        60         70         80         90        100
QKFHAHKAVL AACSDYFRIL LEPGVIQDVL AAGSHLQLLE LLNLCSHYLI 
       110        120        130        140        150
QELNSFNYLD LYRLADLFNL TLLEKAVIDF LVKHLSELLK SRPEEVLTLP 
       160        170        180        190        200
YCLLQEVLKS DRLTSLSEEQ IWQLAVRWLE HNCHYQYMDE LLQYIRFGLM 
       210        220        230        240        250
DVDTLHTVAL SHPLVQASET ATALVNEALE YHQSIYAQPV WQTRRTKPRF 
       260        270        280        290        300
QSDTLYIIGG KKREVCKVKE LRYFNPVDQE NALIAAIANW SELAPMPVGR 
       310        320        330        340        350
SHHCVAVMGD FLFVAGGEVE HASGRTCAVR TACRYDPRSN SWAEIAPMKN 
       360        370        380        390        400
CREHFVLGAM EEYLYAVGGR NELRQVLPTV ERYCPKKNKW TFVQSFDRSL 
       410        420        430        440        450
SCHAGYVADG LLWISGGVTN TAQYQNRLMV YEPNQNKWIS RSPMLQRRVY 
       460        470        480        490        500
HSMAAVQRKL YVLGGNDLDY NNDRILVRHI DSYNIDTDQW TRCNFNLLTG 
       510        520        530        540        550
QNESGVAVHN GRIYLVGGYS IWTNEPLACI QVLDVSREGK EEVFYGPTLP 
       560        570        580 
FASNGIAACF LPAPYFTCPN LQTLQVPHHR IGTI

Note: No experimental confirmation available.

Show »

Length:584

Mass (Da):66,562

Checksum:ⁱ6948DE1F0828FB14

GO

Isoform 3 (identifier: Q96NJ5-3) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
69-104: Missing.
105-137: Missing.

« Hide

        10         20         30         40         50
MPSERCLSIQ EMLTGQRLCH SESHNDSVLA ALNQQRSDGI LCDITLIAEE 
        60         70         80         90        100
QKFHAHKAVL AACSDYFREL NSFNYLDLYR LADLFNLTLL EKAVIDFLVK 
       110        120        130        140        150
HLSELLKSRP EEVLTLPYCL LQEVLKSDRL TSLSEEQIWQ LAVRWLEHNC 
       160        170        180        190        200
HYQYMDELLQ YIRFGLMDVD TLHTVALSHP LVQASETATA LVNEALEYHQ 
       210        220        230        240        250
SIYAQPVWQT RRTKPRFQSD TLYIIGGKKR EVCKVKELRY FNPVDQENAL 
       260        270        280        290        300
IAAIANWSEL APMPVGRSHH CVAVMGDFLF VAGGEVEHAS GRTCAVRTAC 
       310        320        330        340        350
RYDPRSNSWA EIAPMKNCRE HFVLGAMEEY LYAVGGRNEL RQVLPTVERY 
       360        370        380        390        400
CPKKNKWTFV QSFDRSLSCH AGYVADGLLW ISGGVTNTAQ YQNRLMVYEP 
       410        420        430        440        450
NQNKWISRSP MLQRRVYHSM AAVQRKLYVL GGNDLDYNND RILVRHIDSY 
       460        470        480        490        500
NIDTDQWTRC NFNLLTGQNE SGVAVHNGRI YLVGGYSIWT NEPLACIQVL 
       510        520        530        540        550
DVSREGKEEV FYGPTLPFAS NGIAACFLPA PYFTCPNLQT LQVPHHRIGT 

I

Note: No experimental confirmation available.

Show »

Length:551

Mass (Da):62,953

Checksum:ⁱABBF742A7ABFC9E4

GO

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Sequence conflictⁱ	331	P → S in BAB70899 (PubMed:14702039).Curated		1

Natural variant

Feature key	Position(s)	DescriptionActions	Length
Natural variantⁱVAR_050053	5	R → C. Corresponds to variant dbSNP:rs35143662Ensembl.	1
Natural variantⁱVAR_028279	129	N → S. Corresponds to variant dbSNP:rs2294763Ensembl.	1
Natural variantⁱVAR_028280	146	D → G. Corresponds to variant dbSNP:rs12662753Ensembl.	1

Alternative sequence

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Alternative sequenceⁱVSP_054888	69 – 104	Missing in isoform 2 and isoform 3. 1 PublicationAdd BLAST		36
Alternative sequenceⁱVSP_054889	105 – 137	Missing in isoform 3. 1 PublicationAdd BLAST		33

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK055292 mRNA. Translation: BAB70899.1. AK295479 mRNA. Translation: BAH12082.1. AK297240 mRNA. Translation: BAH12528.1. AL033375, AL023656, AL356958 Genomic DNA. Translation: CAI19824.1. AL023656, AL033375, AL356958 Genomic DNA. Translation: CAI20428.1. AL356958, AL023656, AL033375 Genomic DNA. Translation: CAI21654.1. CH471051 Genomic DNA. Translation: EAW48499.1. CH471051 Genomic DNA. Translation: EAW48500.1. AB067487 mRNA. Translation: BAB67793.1.
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS5038.1. [Q96NJ5-1] CCDS69154.1. [Q96NJ5-2] CCDS69155.1. [Q96NJ5-3]
NCBI Reference Sequences More...RefSeqⁱ	NP_001273179.1. NM_001286250.1. [Q96NJ5-2] NP_001273180.1. NM_001286251.1. [Q96NJ5-3] NP_001273183.1. NM_001286254.2. NP_001310181.1. NM_001323252.1. [Q96NJ5-1] NP_001310182.1. NM_001323253.1. NP_001310183.1. NM_001323254.1. NP_001310184.1. NM_001323255.1. NP_001310185.1. NM_001323256.1. NP_001310186.1. NM_001323257.1. NP_001310188.1. NM_001323259.1. NP_001310189.1. NM_001323260.1. NP_001310190.1. NM_001323261.1. NP_001310191.1. NM_001323262.1. NP_001310192.1. NM_001323263.1. NP_001310193.1. NM_001323264.1. NP_443136.2. NM_052904.3. [Q96NJ5-1]
UniGeneⁱ	Hs.45056. Hs.742749.

Genome annotation databases

Ensemblⁱ	ENST00000369261; ENSP00000358265; ENSG00000186231. [Q96NJ5-1] ENST00000536676; ENSP00000440382; ENSG00000186231. [Q96NJ5-2] ENST00000539200; ENSP00000441527; ENSG00000186231. [Q96NJ5-3]
GeneIDⁱ	114792.
KEGGⁱ	hsa:114792.
UCSC genome browser More...UCSCⁱ	uc010kcm.2. human. [Q96NJ5-1]

Keywords - Coding sequence diversityⁱ

Alternative splicing, Polymorphism

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK055292 mRNA. Translation: BAB70899.1. AK295479 mRNA. Translation: BAH12082.1. AK297240 mRNA. Translation: BAH12528.1. AL033375, AL023656, AL356958 Genomic DNA. Translation: CAI19824.1. AL023656, AL033375, AL356958 Genomic DNA. Translation: CAI20428.1. AL356958, AL023656, AL033375 Genomic DNA. Translation: CAI21654.1. CH471051 Genomic DNA. Translation: EAW48499.1. CH471051 Genomic DNA. Translation: EAW48500.1. AB067487 mRNA. Translation: BAB67793.1.
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS5038.1. [Q96NJ5-1] CCDS69154.1. [Q96NJ5-2] CCDS69155.1. [Q96NJ5-3]
NCBI Reference Sequences More...RefSeqⁱ	NP_001273179.1. NM_001286250.1. [Q96NJ5-2] NP_001273180.1. NM_001286251.1. [Q96NJ5-3] NP_001273183.1. NM_001286254.2. NP_001310181.1. NM_001323252.1. [Q96NJ5-1] NP_001310182.1. NM_001323253.1. NP_001310183.1. NM_001323254.1. NP_001310184.1. NM_001323255.1. NP_001310185.1. NM_001323256.1. NP_001310186.1. NM_001323257.1. NP_001310188.1. NM_001323259.1. NP_001310189.1. NM_001323260.1. NP_001310190.1. NM_001323261.1. NP_001310191.1. NM_001323262.1. NP_001310192.1. NM_001323263.1. NP_001310193.1. NM_001323264.1. NP_443136.2. NM_052904.3. [Q96NJ5-1]
UniGeneⁱ	Hs.45056. Hs.742749.

3D structure databases

ProteinModelPortalⁱ	Q96NJ5.
SMRⁱ	Q96NJ5.
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	125354. 10 interactors.
IntActⁱ	Q96NJ5. 2 interactors.
STRINGⁱ	9606.ENSP00000358265.

PTM databases

iPTMnetⁱ	Q96NJ5.
PhosphoSitePlusⁱ	Q96NJ5.

Polymorphism and mutation databases

BioMutaⁱ	KLHL32.
DMDMⁱ	116241269.

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q96NJ5.
PaxDbⁱ	Q96NJ5.
PeptideAtlas More...PeptideAtlasⁱ	Q96NJ5.
PRIDEⁱ	Q96NJ5.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000369261; ENSP00000358265; ENSG00000186231. [Q96NJ5-1] ENST00000536676; ENSP00000440382; ENSG00000186231. [Q96NJ5-2] ENST00000539200; ENSP00000441527; ENSG00000186231. [Q96NJ5-3]
GeneIDⁱ	114792.
KEGGⁱ	hsa:114792.
UCSC genome browser More...UCSCⁱ	uc010kcm.2. human. [Q96NJ5-1]

Organism-specific databases

CTDⁱ	114792.
DisGeNET More...DisGeNETⁱ	114792.
GeneCardsⁱ	KLHL32.
H-InvDBⁱ	HIX0006082.
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:21221. KLHL32.
Human Protein Atlas More...HPAⁱ	HPA039150.
neXtProtⁱ	NX_Q96NJ5.
Open Targets More...OpenTargetsⁱ	ENSG00000186231.
PharmGKBⁱ	PA162393552.
HUGEⁱ	Search...
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG1072. Eukaryota. ENOG4110X8D. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000118825.
HOGENOMⁱ	HOG000231583.
HOVERGENⁱ	HBG107125.
InParanoidⁱ	Q96NJ5.
KEGG Orthology (KO) More...KOⁱ	K10468.
OMAⁱ	QIWQLAV.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G035Z.
PhylomeDBⁱ	Q96NJ5.
TreeFamⁱ	TF328485.

Miscellaneous databases

GenomeRNAiⁱ	114792.
Protein Ontology More...PROⁱ	PR:Q96NJ5.

Gene expression databases

Bgeeⁱ	ENSG00000186231.
CleanExⁱ	HS_KLHL32.
ExpressionAtlasⁱ	Q96NJ5. baseline and differential.
Genevisibleⁱ	Q96NJ5. HS.

Family and domain databases

Gene3Dⁱ	2.120.10.80. 2 hits.
InterProⁱ	View protein in InterPro IPR011705. BACK. IPR017096. BTB-kelch_protein. IPR000210. BTB/POZ_dom. IPR015915. Kelch-typ_b-propeller. IPR006652. Kelch_1. IPR030570. KLHL32. IPR011333. SKP1/BTB/POZ.
PANTHERⁱ	PTHR24412:SF319. PTHR24412:SF319. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF07707. BACK. 1 hit. PF00651. BTB. 1 hit. PF01344. Kelch_1. 3 hits.
PIRSFⁱ	PIRSF037037. Kelch-like_protein_gigaxonin. 1 hit.
SMARTⁱ	View protein in SMART SM00875. BACK. 1 hit. SM00225. BTB. 1 hit. SM00612. Kelch. 5 hits.
SUPFAMⁱ	SSF54695. SSF54695. 1 hit.
PROSITEⁱ	View protein in PROSITE PS50097. BTB. 1 hit.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	KLH32_HUMAN
Accessionⁱ	Q96NJ5Primary (citable) accession number: Q96NJ5 Secondary accession number(s): B7Z346 , B7Z4E2, E1P528, Q5THT0, Q96PY7
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	January 16, 2004
	Last sequence update:	October 17, 2006
	Last modified:	June 7, 2017
	This is version 126 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

Human chromosome 6
Human chromosome 6: entries, gene names and cross-references to MIM
Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations
Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations

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UniProtKB - Q96NJ5 (KLH32_HUMAN)

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Kelch-like protein 32

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3)i

Experimental Info

Natural variant

Alternative sequence

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Documents

Functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequences (3)ⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ