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Q96NA2

- RILP_HUMAN

UniProt

Q96NA2 - RILP_HUMAN

Protein

Rab-interacting lysosomal protein

Gene

RILP

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 109 (01 Oct 2014)
      Sequence version 1 (01 Dec 2001)
      Previous versions | rss
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    Functioni

    Rab effector playing a role in late endocytic transport to degradative compartments. Involved in the regulation of lysosomal morphology and distribution. Induces recruitment of dynein-dynactin motor complexes to Rab7A-containing late endosome and lysosome compartments. Promotes centripetal migration of phagosomes and the fusion of phagosomes with the late endosomes and lysosomes.4 Publications

    GO - Molecular functioni

    1. protein binding Source: UniProtKB
    2. Rab GTPase binding Source: UniProtKB

    GO - Biological processi

    1. antigen processing and presentation of exogenous peptide antigen via MHC class II Source: Reactome
    2. endosome to lysosome transport Source: BHF-UCL
    3. protein transport Source: UniProtKB

    Keywords - Biological processi

    Protein transport, Transport

    Enzyme and pathway databases

    ReactomeiREACT_121399. MHC class II antigen presentation.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Rab-interacting lysosomal protein
    Gene namesi
    Name:RILP
    ORF Names:PP10141
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 17

    Organism-specific databases

    HGNCiHGNC:30266. RILP.

    Subcellular locationi

    Endomembrane system. Late endosome membrane. Lysosome membrane. Cytoplasmic vesiclephagosome membrane
    Note: Associated with late endosomal, lysosomal and phagosomal membranes. The interaction with RAB7A is necessary for its recruitment to phagosomes.

    GO - Cellular componenti

    1. late endosome Source: UniProtKB
    2. late endosome membrane Source: UniProtKB-SubCell
    3. lysosomal membrane Source: UniProtKB
    4. lysosome Source: BHF-UCL
    5. mitochondrion Source: Ensembl
    6. phagocytic vesicle membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasmic vesicle, Endosome, Lysosome, Membrane

    Pathology & Biotechi

    Mutagenesis

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Mutagenesisi248 – 2481F → A: Strongly reduces dimerization and localization to late endosomal/lysosomal compartments. 1 Publication
    Mutagenesisi251 – 2511I → A: Abolishes dimerization, interaction with RAB7A and localization to late endosomal/lysosomal compartments. 1 Publication
    Mutagenesisi252 – 2521L → A: Abolishes interaction with RAB7A and localization to late endosomal/lysosomal compartments. 1 Publication
    Mutagenesisi255 – 2551R → A: Abolishes dimerization, interaction with RAB7A and localization to late endosomal/lysosomal compartments. 1 Publication
    Mutagenesisi258 – 2581L → A: Reduces dimerization, interaction with RAB7A and localization to late endosomal/lysosomal compartments. 1 Publication
    Mutagenesisi304 – 3041K → A: Abolishes interaction with RAB7A and localization to late endosomal/lysosomal compartments. 1 Publication
    Mutagenesisi305 – 3051M → A: Abolishes interaction with RAB7A and localization to late endosomal/lysosomal compartments. 1 Publication
    Mutagenesisi306 – 3061L → A: Abolishes interaction with RAB7A and localization to late endosomal/lysosomal compartments. 1 Publication

    Organism-specific databases

    PharmGKBiPA134915969.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 401401Rab-interacting lysosomal proteinPRO_0000097339Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei314 – 3141Phosphoserine1 Publication
    Modified residuei315 – 3151Phosphoserine1 Publication

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    MaxQBiQ96NA2.
    PaxDbiQ96NA2.
    PRIDEiQ96NA2.

    PTM databases

    PhosphoSiteiQ96NA2.

    Expressioni

    Tissue specificityi

    Ubiquitous. Strongly expressed in fetal heart, heart, stomach, spleen, adrenal gland, thyroid gland, salivary gland, fetal liver, liver and lung. Poorly expressed in brain.3 Publications

    Gene expression databases

    ArrayExpressiQ96NA2.
    BgeeiQ96NA2.
    CleanExiHS_RILP.
    GenevestigatoriQ96NA2.

    Organism-specific databases

    HPAiHPA052041.

    Interactioni

    Subunit structurei

    Homodimer. Each subunit can interact with either RAB7A or RAB34. Interacts with CLN3.6 Publications

    Protein-protein interaction databases

    BioGridi123679. 6 interactions.
    IntActiQ96NA2. 3 interactions.
    STRINGi9606.ENSP00000301336.

    Structurei

    Secondary structure

    1
    401
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Helixi248 – 27629
    Helixi284 – 30623

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    1YHNX-ray3.00B244-308[»]
    ProteinModelPortaliQ96NA2.
    SMRiQ96NA2. Positions 244-308.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiQ96NA2.

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini236 – 27035RILP-likeAdd
    BLAST

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni272 – 33362Necessary for the interaction with RAB7A and RAB34, lysosomal distribution and morphologyAdd
    BLAST

    Coiled coil

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Coiled coili75 – 181107Sequence AnalysisAdd
    BLAST

    Sequence similaritiesi

    Contains 1 RILP-like domain.Curated

    Keywords - Domaini

    Coiled coil

    Phylogenomic databases

    eggNOGiNOG28812.
    HOGENOMiHOG000007529.
    HOVERGENiHBG082629.
    InParanoidiQ96NA2.
    KOiK13883.
    OMAiEPEWATA.
    PhylomeDBiQ96NA2.
    TreeFamiTF313489.

    Family and domain databases

    InterProiIPR019143. JNK/Rab-associated_protein-1_N.
    IPR021563. RILP.
    [Graphical view]
    PfamiPF09744. Jnk-SapK_ap_N. 1 hit.
    PF11461. RILP. 1 hit.
    [Graphical view]

    Sequences (2)i

    Sequence statusi: Complete.

    This entry describes 2 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q96NA2-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MEPRRAAPGV PGWGSREAAG SASAAELVYH LAGALGTELQ DLARRFGPEA    50
    AAGLVPLVVR ALELLEQAAV GPAPDSLQVS AQPAEQELRR LREENERLRR 100
    ELRAGPQEER ALLRQLKEVT DRQRDELRAH NRDLRQRGQE TEALQEQLQR 150
    LLLVNAELRH KLAAMQTQLR AAQDRERERQ QPGEAATPQA KERARGQAGR 200
    PGHQHGQEPE WATAGAGAPG NPEDPAEAAQ QLGRPSEAGQ CRFSREEFEQ 250
    ILQERNELKA KVFLLKEELA YFQRELLTDH RVPGLLLEAM KVAVRKQRKK 300
    IKAKMLGTPE EAESSEDEAG PWILLSDDKG DHPPPPESKI QSFFGLWYRG 350
    KAESSEDETS SPAPSKLGGE EEAQPQSPAP DPPCSALHEH LCLGASAAPE 400
    A 401
    Length:401
    Mass (Da):44,200
    Last modified:December 1, 2001 - v1
    Checksum:i1057A1DAC2FFED94
    GO
    Isoform 2 (identifier: Q96NA2-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-210: Missing.
         211-213: WAT → MGA

    Show »
    Length:191
    Mass (Da):20,726
    Checksum:i76673702E0FF4FFD
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti284 – 2841G → S in CAC33443. (PubMed:11179213)Curated

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti81 – 811A → T.1 Publication
    Corresponds to variant rs9909321 [ dbSNP | Ensembl ].
    VAR_051321
    Natural varianti281 – 2811R → Q.
    Corresponds to variant rs34982553 [ dbSNP | Ensembl ].
    VAR_034417

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei1 – 210210Missing in isoform 2. 1 PublicationVSP_016043Add
    BLAST
    Alternative sequencei211 – 2133WAT → MGA in isoform 2. 1 PublicationVSP_016044

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ404317 mRNA. Translation: CAC33443.1.
    AK055755 mRNA. Translation: BAB71003.1.
    AK314767 mRNA. Translation: BAG37305.1.
    AF370391 mRNA. Translation: AAQ15227.1.
    AJ278711 mRNA. Translation: CAC82174.1.
    BC004961 mRNA. Translation: AAH04961.1.
    BC031621 mRNA. Translation: AAH31621.1.
    CCDSiCCDS11009.1. [Q96NA2-1]
    RefSeqiNP_113618.2. NM_031430.2. [Q96NA2-1]
    UniGeneiHs.534497.

    Genome annotation databases

    EnsembliENST00000301336; ENSP00000301336; ENSG00000167705. [Q96NA2-1]
    GeneIDi83547.
    KEGGihsa:83547.
    UCSCiuc002ftd.3. human. [Q96NA2-1]

    Polymorphism databases

    DMDMi74732524.

    Keywords - Coding sequence diversityi

    Alternative splicing, Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ404317 mRNA. Translation: CAC33443.1 .
    AK055755 mRNA. Translation: BAB71003.1 .
    AK314767 mRNA. Translation: BAG37305.1 .
    AF370391 mRNA. Translation: AAQ15227.1 .
    AJ278711 mRNA. Translation: CAC82174.1 .
    BC004961 mRNA. Translation: AAH04961.1 .
    BC031621 mRNA. Translation: AAH31621.1 .
    CCDSi CCDS11009.1. [Q96NA2-1 ]
    RefSeqi NP_113618.2. NM_031430.2. [Q96NA2-1 ]
    UniGenei Hs.534497.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    1YHN X-ray 3.00 B 244-308 [» ]
    ProteinModelPortali Q96NA2.
    SMRi Q96NA2. Positions 244-308.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 123679. 6 interactions.
    IntActi Q96NA2. 3 interactions.
    STRINGi 9606.ENSP00000301336.

    PTM databases

    PhosphoSitei Q96NA2.

    Polymorphism databases

    DMDMi 74732524.

    Proteomic databases

    MaxQBi Q96NA2.
    PaxDbi Q96NA2.
    PRIDEi Q96NA2.

    Protocols and materials databases

    DNASUi 83547.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000301336 ; ENSP00000301336 ; ENSG00000167705 . [Q96NA2-1 ]
    GeneIDi 83547.
    KEGGi hsa:83547.
    UCSCi uc002ftd.3. human. [Q96NA2-1 ]

    Organism-specific databases

    CTDi 83547.
    GeneCardsi GC17M001549.
    HGNCi HGNC:30266. RILP.
    HPAi HPA052041.
    MIMi 607848. gene.
    neXtProti NX_Q96NA2.
    PharmGKBi PA134915969.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG28812.
    HOGENOMi HOG000007529.
    HOVERGENi HBG082629.
    InParanoidi Q96NA2.
    KOi K13883.
    OMAi EPEWATA.
    PhylomeDBi Q96NA2.
    TreeFami TF313489.

    Enzyme and pathway databases

    Reactomei REACT_121399. MHC class II antigen presentation.

    Miscellaneous databases

    EvolutionaryTracei Q96NA2.
    GeneWikii RILP_(gene).
    GenomeRNAii 83547.
    NextBioi 72481.
    PROi Q96NA2.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q96NA2.
    Bgeei Q96NA2.
    CleanExi HS_RILP.
    Genevestigatori Q96NA2.

    Family and domain databases

    InterProi IPR019143. JNK/Rab-associated_protein-1_N.
    IPR021563. RILP.
    [Graphical view ]
    Pfami PF09744. Jnk-SapK_ap_N. 1 hit.
    PF11461. RILP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Rab-interacting lysosomal protein (RILP): the Rab7 effector required for transport to lysosomes."
      Cantalupo G., Alifano P., Roberti V., Bruni C.B., Bucci C.
      EMBO J. 20:683-693(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), FUNCTION IN LATE ENDOCYTOSIS, INTERACTION WITH RAB7A, SUBCELLULAR LOCATION, TISSUE SPECIFICITY.
      Tissue: Cervix carcinoma.
    2. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), VARIANT THR-81.
      Tissue: Kidney and Thalamus.
    3. "Large-scale cDNA transfection screening for genes related to cancer development and progression."
      Wan D., Gong Y., Qin W., Zhang P., Li J., Wei L., Zhou X., Li H., Qiu X., Zhong F., He L., Yu J., Yao G., Jiang H., Qian L., Yu Y., Shu H., Chen X.
      , Xu H., Guo M., Pan Z., Chen Y., Ge C., Yang S., Gu J.
      Proc. Natl. Acad. Sci. U.S.A. 101:15724-15729(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
    4. "Study of 100 skeletal muscle full length mRNA (Telethon project B41)."
      Frigimelica E., Lanfranchi G.
      Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
      Tissue: Skeletal muscle.
    5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
      Tissue: Brain, Lung, Testis and Uterus.
    6. "Expression analysis and chromosomal assignment of PRA1 and RILP genes."
      Bucci C., De Gregorio L., Bruni C.B.
      Biochem. Biophys. Res. Commun. 286:815-819(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: TISSUE SPECIFICITY.
    7. "The Rab7 effector protein RILP controls lysosomal transport by inducing the recruitment of dynein-dynactin motors."
      Jordens I., Fernandez-Borja M., Marsman M., Dusseljee S., Janssen L., Calafat J., Janssen H., Wubbolts R., Neefjes J.
      Curr. Biol. 11:1680-1685(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION IN DYNEIN-DYNACTIN COMPLEX RECRUITMENT.
    8. "Interorganellar regulation of lysosome positioning by the Golgi apparatus through Rab34 interaction with Rab-interacting lysosomal protein."
      Wang T., Hong W.
      Mol. Biol. Cell 13:4317-4332(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: INTERACTION WITH RAB34.
    9. "Phagosomes fuse with late endosomes and/or lysosomes by extension of membrane protrusions along microtubules: role of Rab7 and RILP."
      Harrison R.E., Bucci C., Vieira O.V., Schroer T.A., Grinstein S.
      Mol. Cell. Biol. 23:6494-6506(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION IN PHAGOSOME MIGRATION AND PHAGOLYSOSOMAL FUSION, SUBCELLULAR LOCATION.
    10. "A unique region of RILP distinguishes it from its related proteins in its regulation of lysosomal morphology and interaction with Rab7 and Rab34."
      Wang T., Wong K.K., Hong W.
      Mol. Biol. Cell 15:815-826(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION IN LYSOSOMAL MORPHOLOGY AND DISTRIBUTION, INTERACTION WITH RAB7A AND RAB34, SUBCELLULAR LOCATION, TISSUE SPECIFICITY.
    11. "The Rab-interacting lysosomal protein, a Rab7 and Rab34 effector, is capable of self-interaction."
      Colucci A.M.R., Campana M.C., Bellopede M., Bucci C.
      Biochem. Biophys. Res. Commun. 334:128-133(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: SUBUNIT.
    12. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-314 AND SER-315, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    13. "Neuronal ceroid lipofuscinosis protein CLN3 interacts with motor proteins and modifies location of late endosomal compartments."
      Uusi-Rauva K., Kyttala A., van der Kant R., Vesa J., Tanhuanpaa K., Neefjes J., Olkkonen V.M., Jalanko A.
      Cell. Mol. Life Sci. 69:2075-2089(2012) [PubMed] [Europe PMC] [Abstract]
      Cited for: INTERACTION WITH CLN3.
    14. "Structural basis for recruitment of RILP by small GTPase Rab7."
      Wu M., Wang T., Loh E., Hong W., Song H.
      EMBO J. 24:1491-1501(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF 244-308 IN COMPLEX WITH RAB7A, SUBUNIT, MUTAGENESIS OF PHE-248; ILE-251; LEU-252; ARG-255; LEU-258; LYS-304; MET-305 AND LEU-306.

    Entry informationi

    Entry nameiRILP_HUMAN
    AccessioniPrimary (citable) accession number: Q96NA2
    Secondary accession number(s): B2RBQ8
    , Q71RE6, Q9BSL3, Q9BYS3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 8, 2005
    Last sequence update: December 1, 2001
    Last modified: October 1, 2014
    This is version 109 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Reference proteome

    Documents

    1. Human chromosome 17
      Human chromosome 17: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    4. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    5. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    6. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3