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Q96N91

- Q96N91_HUMAN

UniProt

Q96N91 - Q96N91_HUMAN

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Protein

V-type proton ATPase subunit a

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli

Functioni

Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase.UniRule annotation

GO - Molecular functioni

  1. hydrogen ion transmembrane transporter activity Source: InterPro

GO - Biological processi

  1. ATP hydrolysis coupled proton transport Source: InterPro
Complete GO annotation...

Keywords - Biological processi

Hydrogen ion transportUniRule annotation, Ion transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
V-type proton ATPase subunit aUniRule annotation
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. proton-transporting V-type ATPase, V0 domain Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PRIDEiQ96N91.

Structurei

3D structure databases

ProteinModelPortaliQ96N91.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the V-ATPase 116 kDa subunit family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

HOGENOMiHOG000037059.
HOVERGENiHBG014606.

Family and domain databases

InterProiIPR002490. V-ATPase_116kDa_su.
[Graphical view]
PANTHERiPTHR11629. PTHR11629. 1 hit.
PfamiPF01496. V_ATPase_I. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q96N91-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTGKLGFIAG VINRERMASF ERLLWRICRG NVYLKFSEMD APLEDPVTKE
60 70 80 90 100
EIQKNIFIIF YQGEQLRQKI KKICDGFRAT VYPCPEPAVE RREMLESVNV
110 120 130 140 150
RLEDLITVIT QTESHRQRLL QEAAANWHSW LIKVQKMKAV YHILNMCNID
160 170 180 190 200
VTQQCVIAEI WFPVADATRI KRALEQGMEL SGSSMAPIMT TVQSKTAPPT
210 220 230 240 250
FNRTNKFTAG FQNIVDAYGV GSYREINPAP YTIITFPFLF AVMFGDCGHG
260 270 280 290 300
TVMLLAALWM ILNERRLLSQ KTDNEIWNTF FHGRYLIHFI NMFLFNYSDS
310 320 330 340 350
SNAPLYKHQQ EVQSFFVVMA LISVPWMLLI KPFILRASHR KSQLQASRIQ
360 370 380 390 400
EDATENIEGD SSSPSSRSGQ RTSADTHGAL DDHGEEFNFG DVFVHQAIHT
410 420 430 440 450
IEYCLGCISN TASYLRLWAL SLAHAQLSEV LWTMVMNSGL QTRGWGGIVG
460 470 480 490 500
VFIIFAVFAV LTVAILLIME GLSAFLHALR LHWVEFQNKF YVGDGYKFSP
510
FSFKHILDGT AEE
Length:513
Mass (Da):58,476
Last modified:December 1, 2001 - v1
Checksum:i1CABB7682F5E4A89
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK055789 mRNA. Translation: BAB71014.1.
UniGeneiHs.98967.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK055789 mRNA. Translation: BAB71014.1 .
UniGenei Hs.98967.

3D structure databases

ProteinModelPortali Q96N91.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q96N91.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

HOGENOMi HOG000037059.
HOVERGENi HBG014606.

Family and domain databases

InterProi IPR002490. V-ATPase_116kDa_su.
[Graphical view ]
PANTHERi PTHR11629. PTHR11629. 1 hit.
Pfami PF01496. V_ATPase_I. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: KidneyImported.

Entry informationi

Entry nameiQ96N91_HUMAN
AccessioniPrimary (citable) accession number: Q96N91
Entry historyi
Integrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: October 29, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.