Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q96N16

- JKIP1_HUMAN

UniProt

Q96N16 - JKIP1_HUMAN

Protein

Janus kinase and microtubule-interacting protein 1

Gene

JAKMIP1

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 92 (01 Oct 2014)
      Sequence version 1 (01 Dec 2001)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Associates with microtubules and may play a role in the microtubule-dependent transport of the GABA-B receptor. May play a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements.3 Publications

    GO - Molecular functioni

    1. GABA receptor binding Source: MGI
    2. protein binding Source: IntAct
    3. RNA binding Source: MGI

    GO - Biological processi

    1. cognition Source: UniProt
    2. protein transport Source: UniProtKB-KW

    Keywords - Biological processi

    Protein transport, Transport

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Janus kinase and microtubule-interacting protein 1
    Alternative name(s):
    GABA-B receptor-binding protein
    Multiple alpha-helices and RNA-linker protein 1
    Short name:
    Marlin-1
    Gene namesi
    Name:JAKMIP1
    Synonyms:GABABRBP, JAMIP1, MARLIN1
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 4

    Organism-specific databases

    HGNCiHGNC:26460. JAKMIP1.

    Subcellular locationi

    Cytoplasmcytoskeleton. Membrane; Peripheral membrane protein
    Note: Colocalizes with the microtubule network. Localizes to the cell body and neurites of hippocampal neurons where it accumulates in granules. Localizes to the tail and to a lower extent to the head of sperm cells.

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-KW
    2. extrinsic component of membrane Source: MGI
    3. microtubule Source: UniProtKB-KW
    4. ribonucleoprotein complex Source: MGI

    Keywords - Cellular componenti

    Cytoplasm, Cytoskeleton, Membrane, Microtubule

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA143485508.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 626626Janus kinase and microtubule-interacting protein 1PRO_0000323008Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei382 – 3821Phosphoserine2 Publications
    Modified residuei470 – 4701Phosphothreonine2 Publications

    Keywords - PTMi

    Phosphoprotein

    Proteomic databases

    MaxQBiQ96N16.
    PaxDbiQ96N16.
    PRIDEiQ96N16.

    PTM databases

    PhosphoSiteiQ96N16.

    Miscellaneous databases

    PMAP-CutDBQ96N16.

    Expressioni

    Tissue specificityi

    Predominantly expressed in neural tissues and lymphoid cells (at protein level). Isoform 2, isoform 3 and isoform 4 are specifically expressed in brain and retina. Isoform 1 and isoform 5 are also detected in liver, lung and skeletal muscle. Also detected in testis and to a lower extent spleen and intestine.2 Publications

    Gene expression databases

    ArrayExpressiQ96N16.
    BgeeiQ96N16.
    CleanExiHS_JAKMIP1.
    GenevestigatoriQ96N16.

    Organism-specific databases

    HPAiHPA044570.

    Interactioni

    Subunit structurei

    Homodimer. Forms a complex with GABBR1 and KIF5B/kinesin-1. Interacts with JAK1 and TYK2.3 Publications

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    HTTP428584EBI-2680803,EBI-466029

    Protein-protein interaction databases

    BioGridi127465. 1 interaction.
    IntActiQ96N16. 3 interactions.

    Structurei

    3D structure databases

    ProteinModelPortaliQ96N16.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni1 – 365365Mediates association with microtubulesAdd
    BLAST
    Regioni365 – 626262Mediates interaction with TYK2 and GABBR1Add
    BLAST

    Coiled coil

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Coiled coili19 – 255237Sequence AnalysisAdd
    BLAST
    Coiled coili284 – 413130Sequence AnalysisAdd
    BLAST
    Coiled coili490 – 604115Sequence AnalysisAdd
    BLAST

    Sequence similaritiesi

    Belongs to the JAKMIP family.Curated

    Keywords - Domaini

    Coiled coil

    Phylogenomic databases

    eggNOGiNOG147883.
    HOVERGENiHBG054249.
    OMAiQHKHTAY.
    OrthoDBiEOG7HHWRJ.
    PhylomeDBiQ96N16.
    TreeFamiTF331900.

    Family and domain databases

    InterProiIPR024836. JAKMIP.
    [Graphical view]
    PANTHERiPTHR18935. PTHR18935. 1 hit.

    Sequences (7)i

    Sequence statusi: Complete.

    This entry describes 7 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q96N16-1) [UniParc]FASTAAdd to Basket

    Also known as: Jakmip1A

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MSKKGRSKGE KPEMETDAVQ MANEELRAKL TSIQIEFQQE KSKVGKLRER    50
    LQEAKLEREQ EQRRHTAYIS ELKAKLHEEK TKELQALREG LIRQHEQEAA 100
    RTAKIKEGEL QRLQATLNVL RDGAADKVKT ALLTEAREEA RRAFDGERLR 150
    LQQEILELKA ARKQAEEALS NCMQADKTKA ADLRAAYQAH QDEVHRIKRE 200
    CERDIRRLMD EIKGKDRVIL ALEKELGVQA GQTQKLLLQK EALDEQLVQV 250
    KEAERHHSSP KRELPPGIGD MVELMGVQDQ HMDERDVRRF QLKIAELNSV 300
    IRKLEDRNTL LADERNELLK RSRETEVQLK PLVEKNKRMN KKNEDLLQSI 350
    QRMEEKIKNL TRENVEMKEK LSAQASLKRH TSLNDLSLTR DEQEIEFLRL 400
    QVLEQQHVID DLSLERERLL RSKRHRGKSL KPPKKHVVET FFGFDEESVD 450
    SETLSETSYN TDRTDRTPAT PEEDLDDATA REEADLRFCQ LTREYQALQR 500
    AYALLQEQVG GTLDAEREAR TREQLQADLL RCQAKIEDLE KLLVEKGQDS 550
    KWVEEKQLLI RTNQDLLEKI YRLEMEENQL KNEMQDAKDQ NELLEFRVLE 600
    LEVRDSICCK LSNGADILFE PKLKFM 626
    Length:626
    Mass (Da):73,209
    Last modified:December 1, 2001 - v1
    Checksum:i6A8E164E8A2A7EFB
    GO
    Isoform 2 (identifier: Q96N16-2) [UniParc]FASTAAdd to Basket

    Also known as: Jakmip1B

    The sequence of this isoform differs from the canonical sequence as follows:
         603-626: VRDSICCKLSNGADILFEPKLKFM → ERERRSPAFN...FFSLAFILWP

    Show »
    Length:831
    Mass (Da):97,436
    Checksum:i331CB5500A662634
    GO
    Isoform 3 (identifier: Q96N16-3) [UniParc]FASTAAdd to Basket

    Also known as: Jakmip1C

    The sequence of this isoform differs from the canonical sequence as follows:
         374-431: QASLKRHTSL...SKRHRGKSLK → HGAAAAGPAE...MTSVSQELGL
         432-626: Missing.

    Note: Dubious isoform produced through aberrant splice sites.

    Show »
    Length:431
    Mass (Da):49,323
    Checksum:i13C02CC36809B13C
    GO
    Isoform 4 (identifier: Q96N16-4) [UniParc]FASTAAdd to Basket

    Also known as: Jakmip1D

    The sequence of this isoform differs from the canonical sequence as follows:
         495-569: YQALQRAYAL...IRTNQDLLEK → DLQAAVEKVR...FFSLAFILWP
         570-626: Missing.

    Note: Dubious isoform produced through aberrant splice sites.

    Show »
    Length:569
    Mass (Da):67,000
    Checksum:i3592DB24973B29D2
    GO
    Isoform 5 (identifier: Q96N16-5) [UniParc]FASTAAdd to Basket

    Also known as: Jakmip1E

    The sequence of this isoform differs from the canonical sequence as follows:
         44-208: Missing.
         415-434: Missing.
         603-626: VRDSICCKLSNGADILFEPKLKFM → ERERRSPAFN...FFSLAFILWP

    Show »
    Length:646
    Mass (Da):75,746
    Checksum:iE0F39B9913C749C8
    GO
    Isoform 6 (identifier: Q96N16-6) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-208: Missing.
         494-520: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:391
    Mass (Da):45,989
    Checksum:i799EBF218498F2B0
    GO
    Isoform 7 (identifier: Q96N16-7) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         44-208: Missing.

    Note: No experimental confirmation available.

    Show »
    Length:461
    Mass (Da):53,973
    Checksum:i6E1F8C344865C8B2
    GO

    Sequence cautioni

    The sequence BAC05325.1 differs from that shown. Reason: Erroneous termination at position 285. Translated as Arg.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti163 – 1631K → N in AAH47075. (PubMed:15489334)Curated

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti251 – 2511K → R.1 Publication
    VAR_039471
    Natural varianti375 – 3751A → V in a colorectal cancer sample; somatic mutation. 1 Publication
    VAR_039472

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei1 – 208208Missing in isoform 6. 1 PublicationVSP_031989Add
    BLAST
    Alternative sequencei44 – 208165Missing in isoform 5 and isoform 7. 2 PublicationsVSP_031990Add
    BLAST
    Alternative sequencei374 – 43158QASLK…GKSLK → HGAAAAGPAENPRTGGQTGV SEAAPERTGGKVFVPFFVFL TSIHSVALMTSVSQELGL in isoform 3. 1 PublicationVSP_031991Add
    BLAST
    Alternative sequencei415 – 43420Missing in isoform 5. 1 PublicationVSP_031992Add
    BLAST
    Alternative sequencei432 – 626195Missing in isoform 3. 1 PublicationVSP_031993Add
    BLAST
    Alternative sequencei494 – 52027Missing in isoform 6. 1 PublicationVSP_031994Add
    BLAST
    Alternative sequencei495 – 56975YQALQ…DLLEK → DLQAAVEKVRRQILRQSREF DSQILRERMELLQQAQQRIR ELEDKLEFQKRHLKELEEKF LFLFLFFSLAFILWP in isoform 4. 1 PublicationVSP_031995Add
    BLAST
    Alternative sequencei570 – 62657Missing in isoform 4. 1 PublicationVSP_031996Add
    BLAST
    Alternative sequencei603 – 62624VRDSI…KLKFM → ERERRSPAFNLQITTFPENH SSALQLFCHQEGVKDVNVSE LMKKLDILGDNGNLRNEEQV AIIQAGTVLALCEKWLKQIE GTEAALTQKMLDLEKEKDLF SRQKGYLEEELDYRKQALDQ AYLKIQDLEATLYTALQQEP GRRAGEALSEGQREDLQAAV EKVRRQILRQSREFDSQILR ERMELLQQAQQRIRELEDKL EFQKRHLKELEEKFLFLFLF FSLAFILWP in isoform 2 and isoform 5. 1 PublicationVSP_031997Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY382340 mRNA. Translation: AAR26235.1.
    AM412307 mRNA. Translation: CAL80778.1.
    AM412308 mRNA. Translation: CAL80779.1.
    AM412309 mRNA. Translation: CAL80780.1.
    AM412310 mRNA. Translation: CAL80781.1.
    AK056126 mRNA. Translation: BAB71098.1.
    AK098536 mRNA. Translation: BAC05325.1. Sequence problems.
    AK295339 mRNA. Translation: BAG58310.1.
    AC092442 Genomic DNA. No translation available.
    AC113615 Genomic DNA. No translation available.
    CH471131 Genomic DNA. Translation: EAW82401.1.
    CH471131 Genomic DNA. Translation: EAW82402.1.
    BC047075 mRNA. Translation: AAH47075.1.
    CCDSiCCDS3385.1. [Q96N16-1]
    CCDS47005.1. [Q96N16-2]
    RefSeqiNP_001092903.1. NM_001099433.1. [Q96N16-2]
    NP_653321.1. NM_144720.3. [Q96N16-1]
    UniGeneiHs.479066.

    Genome annotation databases

    EnsembliENST00000282924; ENSP00000282924; ENSG00000152969. [Q96N16-1]
    ENST00000409021; ENSP00000386711; ENSG00000152969. [Q96N16-2]
    ENST00000409371; ENSP00000387042; ENSG00000152969. [Q96N16-5]
    ENST00000409831; ENSP00000386925; ENSG00000152969. [Q96N16-1]
    ENST00000410077; ENSP00000386745; ENSG00000152969. [Q96N16-7]
    GeneIDi152789.
    KEGGihsa:152789.
    UCSCiuc003giu.4. human. [Q96N16-1]
    uc010idb.1. human. [Q96N16-2]
    uc010idc.1. human. [Q96N16-5]

    Polymorphism databases

    DMDMi74732477.

    Keywords - Coding sequence diversityi

    Alternative splicing, Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY382340 mRNA. Translation: AAR26235.1 .
    AM412307 mRNA. Translation: CAL80778.1 .
    AM412308 mRNA. Translation: CAL80779.1 .
    AM412309 mRNA. Translation: CAL80780.1 .
    AM412310 mRNA. Translation: CAL80781.1 .
    AK056126 mRNA. Translation: BAB71098.1 .
    AK098536 mRNA. Translation: BAC05325.1 . Sequence problems.
    AK295339 mRNA. Translation: BAG58310.1 .
    AC092442 Genomic DNA. No translation available.
    AC113615 Genomic DNA. No translation available.
    CH471131 Genomic DNA. Translation: EAW82401.1 .
    CH471131 Genomic DNA. Translation: EAW82402.1 .
    BC047075 mRNA. Translation: AAH47075.1 .
    CCDSi CCDS3385.1. [Q96N16-1 ]
    CCDS47005.1. [Q96N16-2 ]
    RefSeqi NP_001092903.1. NM_001099433.1. [Q96N16-2 ]
    NP_653321.1. NM_144720.3. [Q96N16-1 ]
    UniGenei Hs.479066.

    3D structure databases

    ProteinModelPortali Q96N16.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 127465. 1 interaction.
    IntActi Q96N16. 3 interactions.

    PTM databases

    PhosphoSitei Q96N16.

    Polymorphism databases

    DMDMi 74732477.

    Proteomic databases

    MaxQBi Q96N16.
    PaxDbi Q96N16.
    PRIDEi Q96N16.

    Protocols and materials databases

    DNASUi 152789.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000282924 ; ENSP00000282924 ; ENSG00000152969 . [Q96N16-1 ]
    ENST00000409021 ; ENSP00000386711 ; ENSG00000152969 . [Q96N16-2 ]
    ENST00000409371 ; ENSP00000387042 ; ENSG00000152969 . [Q96N16-5 ]
    ENST00000409831 ; ENSP00000386925 ; ENSG00000152969 . [Q96N16-1 ]
    ENST00000410077 ; ENSP00000386745 ; ENSG00000152969 . [Q96N16-7 ]
    GeneIDi 152789.
    KEGGi hsa:152789.
    UCSCi uc003giu.4. human. [Q96N16-1 ]
    uc010idb.1. human. [Q96N16-2 ]
    uc010idc.1. human. [Q96N16-5 ]

    Organism-specific databases

    CTDi 152789.
    GeneCardsi GC04M005962.
    HGNCi HGNC:26460. JAKMIP1.
    HPAi HPA044570.
    MIMi 611195. gene.
    neXtProti NX_Q96N16.
    PharmGKBi PA143485508.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG147883.
    HOVERGENi HBG054249.
    OMAi QHKHTAY.
    OrthoDBi EOG7HHWRJ.
    PhylomeDBi Q96N16.
    TreeFami TF331900.

    Miscellaneous databases

    GenomeRNAii 152789.
    NextBioi 35472147.
    PMAP-CutDB Q96N16.
    PROi Q96N16.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q96N16.
    Bgeei Q96N16.
    CleanExi HS_JAKMIP1.
    Genevestigatori Q96N16.

    Family and domain databases

    InterProi IPR024836. JAKMIP.
    [Graphical view ]
    PANTHERi PTHR18935. PTHR18935. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), FUNCTION, INTERACTION WITH GABBR1, SUBCELLULAR LOCATION.
      Tissue: Brain.
    2. "Identification and expression analysis of novel Jakmip1 transcripts."
      Costa V., Conte I., Ziviello C., Casamassimi A., Alfano G., Banfi S., Ciccodicola A.
      Gene 402:1-8(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 2; 3; 4 AND 5), TISSUE SPECIFICITY, VARIANT ARG-251.
      Tissue: Brain.
    3. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1; 6 AND 7).
      Tissue: Caudate nucleus, Teratocarcinoma and Testis.
    4. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
      , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
      Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    5. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    6. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
      Tissue: Brain.
    7. "Jamip1 (marlin-1) defines a family of proteins interacting with Janus kinases and microtubules."
      Steindler C., Li Z., Algarte M., Alcover A., Libri V., Ragimbeau J., Pellegrini S.
      J. Biol. Chem. 279:43168-43177(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, INTERACTION WITH JAK1 AND TYK2, OLIGOMERIZATION, SUBCELLULAR LOCATION, PHOSPHORYLATION, TISSUE SPECIFICITY.
    8. "Marlin-1 and conventional kinesin link GABAB receptors to the cytoskeleton and regulate receptor transport."
      Vidal R.L., Ramirez O.A., Sandoval L., Koenig-Robert R., Haertel S., Couve A.
      Mol. Cell. Neurosci. 35:501-512(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, IDENTIFICATION IN A COMPLEX WITH GABBR1 AND KIF5B.
    9. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
      Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-382 AND THR-470, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Leukemic T-cell.
    10. Cited for: VARIANT [LARGE SCALE ANALYSIS] VAL-375.

    Entry informationi

    Entry nameiJKIP1_HUMAN
    AccessioniPrimary (citable) accession number: Q96N16
    Secondary accession number(s): A6H2J2
    , A6H2J3, A6H2J4, A6H2J5, A8MTK6, B4DHZ8, B8ZZR7, D3DVT0, Q86Y69, Q8N7G3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 18, 2008
    Last sequence update: December 1, 2001
    Last modified: October 1, 2014
    This is version 92 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 4
      Human chromosome 4: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    4. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    5. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3