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Protein

Uncharacterized protein C7orf26

Gene

C7orf26

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein C7orf26
Gene namesi
Name:C7orf26
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 7

Organism-specific databases

HGNCiHGNC:21702. C7orf26.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134951741.

Polymorphism and mutation databases

BioMutaiC7orf26.
DMDMi33301033.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 449449Uncharacterized protein C7orf26PRO_0000089582Add
BLAST

Proteomic databases

EPDiQ96N11.
MaxQBiQ96N11.
PaxDbiQ96N11.
PeptideAtlasiQ96N11.
PRIDEiQ96N11.

PTM databases

iPTMnetiQ96N11.

Expressioni

Gene expression databases

BgeeiQ96N11.
CleanExiHS_C7orf26.
ExpressionAtlasiQ96N11. baseline and differential.
GenevisibleiQ96N11. HS.

Organism-specific databases

HPAiHPA052175.

Interactioni

Protein-protein interaction databases

BioGridi122499. 11 interactions.
IntActiQ96N11. 2 interactions.
MINTiMINT-1419805.
STRINGi9606.ENSP00000340220.

Structurei

3D structure databases

ProteinModelPortaliQ96N11.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410IHBH. Eukaryota.
ENOG411039P. LUCA.
GeneTreeiENSGT00390000011370.
HOGENOMiHOG000082529.
HOVERGENiHBG050923.
InParanoidiQ96N11.
OMAiIVSWIFE.
OrthoDBiEOG76QFHX.
PhylomeDBiQ96N11.
TreeFamiTF324587.

Family and domain databases

InterProiIPR027844. DUF4507.
[Graphical view]
PfamiPF14964. DUF4507. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q96N11-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MSDIRHSLLR RDALSAAKEV LYHLDIYFSS QLQSAPLPIV DKGPVELLEE
60 70 80 90 100
FVFQVPKERS AQPKRLNSLQ ELQLLEIMCN YFQEQTKDSV RQIIFSSLFS
110 120 130 140 150
PQGNKADDSR MSLLGKLVSM AVAVCRIPVL ECAASWLQRT PVVYCVRLAK
160 170 180 190 200
ALVDDYCCLV PGSIQTLKQI FSASPRFCCQ FITSVTALYD LSSDDLIPPM
210 220 230 240 250
DLLEMIVTWI FEDPRLILIT FLNTPIAANL PIGFLELTPL VGLIRWCVKA
260 270 280 290 300
PLAYKRKKKP PLSNGHVSNK VTKDPGVGMD RDSHLLYSKL HLSVLQVLMT
310 320 330 340 350
LQLHLTEKNL YGRLGLILFD HMVPLVEEIN RLADELNPLN ASQEIELSLD
360 370 380 390 400
RLAQALQVAM ASGALLCTRD DLRTLCSRLP HNNLLQLVIS GPVQQSPHAA
410 420 430 440
LPPGFYPHIH TPPLGYGAVP AHPAAHPALP THPGHTFISG VTFPFRPIR
Length:449
Mass (Da):50,047
Last modified:December 1, 2001 - v1
Checksum:iCECD14EB3E97A6BA
GO
Isoform 2 (identifier: Q96N11-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     65-83: Missing.
     215-292: Missing.

Show »
Length:352
Mass (Da):39,027
Checksum:i987A7AE66E21F842
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti245 – 2451R → C.
Corresponds to variant rs35534502 [ dbSNP | Ensembl ].
VAR_061593

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei65 – 8319Missing in isoform 2. 1 PublicationVSP_007907Add
BLAST
Alternative sequencei215 – 29278Missing in isoform 2. 1 PublicationVSP_007908Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK056149 mRNA. Translation: BAB71104.1.
BC005121 mRNA. Translation: AAH05121.1.
BC001076 mRNA. Translation: AAH01076.1.
CCDSiCCDS5353.1. [Q96N11-1]
CCDS78206.1. [Q96N11-2]
RefSeqiNP_001289968.1. NM_001303039.1. [Q96N11-2]
NP_076972.2. NM_024067.3. [Q96N11-1]
UniGeneiHs.487511.

Genome annotation databases

EnsembliENST00000344417; ENSP00000340220; ENSG00000146576. [Q96N11-1]
ENST00000359073; ENSP00000351974; ENSG00000146576. [Q96N11-2]
GeneIDi79034.
KEGGihsa:79034.
UCSCiuc003sqo.2. human. [Q96N11-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK056149 mRNA. Translation: BAB71104.1.
BC005121 mRNA. Translation: AAH05121.1.
BC001076 mRNA. Translation: AAH01076.1.
CCDSiCCDS5353.1. [Q96N11-1]
CCDS78206.1. [Q96N11-2]
RefSeqiNP_001289968.1. NM_001303039.1. [Q96N11-2]
NP_076972.2. NM_024067.3. [Q96N11-1]
UniGeneiHs.487511.

3D structure databases

ProteinModelPortaliQ96N11.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi122499. 11 interactions.
IntActiQ96N11. 2 interactions.
MINTiMINT-1419805.
STRINGi9606.ENSP00000340220.

PTM databases

iPTMnetiQ96N11.

Polymorphism and mutation databases

BioMutaiC7orf26.
DMDMi33301033.

Proteomic databases

EPDiQ96N11.
MaxQBiQ96N11.
PaxDbiQ96N11.
PeptideAtlasiQ96N11.
PRIDEiQ96N11.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000344417; ENSP00000340220; ENSG00000146576. [Q96N11-1]
ENST00000359073; ENSP00000351974; ENSG00000146576. [Q96N11-2]
GeneIDi79034.
KEGGihsa:79034.
UCSCiuc003sqo.2. human. [Q96N11-1]

Organism-specific databases

CTDi79034.
GeneCardsiC7orf26.
HGNCiHGNC:21702. C7orf26.
HPAiHPA052175.
neXtProtiNX_Q96N11.
PharmGKBiPA134951741.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IHBH. Eukaryota.
ENOG411039P. LUCA.
GeneTreeiENSGT00390000011370.
HOGENOMiHOG000082529.
HOVERGENiHBG050923.
InParanoidiQ96N11.
OMAiIVSWIFE.
OrthoDBiEOG76QFHX.
PhylomeDBiQ96N11.
TreeFamiTF324587.

Miscellaneous databases

ChiTaRSiC7orf26. human.
GenomeRNAii79034.
PROiQ96N11.

Gene expression databases

BgeeiQ96N11.
CleanExiHS_C7orf26.
ExpressionAtlasiQ96N11. baseline and differential.
GenevisibleiQ96N11. HS.

Family and domain databases

InterProiIPR027844. DUF4507.
[Graphical view]
PfamiPF14964. DUF4507. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
    Tissue: Lung.

Entry informationi

Entry nameiCG026_HUMAN
AccessioniPrimary (citable) accession number: Q96N11
Secondary accession number(s): Q9BQ43
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 25, 2003
Last sequence update: December 1, 2001
Last modified: July 6, 2016
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 7
    Human chromosome 7: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.