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Protein

Protein FAM218A

Gene

FAM218A

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Protein FAM218A
Gene namesi
Name:FAM218A
Synonyms:C4orf39
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 4

Organism-specific databases

HGNCiHGNC:26466. FAM218A.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA162379827.

Polymorphism and mutation databases

BioMutaiFAM218A.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 157157Protein FAM218APRO_0000340724Add
BLAST

Proteomic databases

PaxDbiQ96MZ4.
PeptideAtlasiQ96MZ4.
PRIDEiQ96MZ4.

PTM databases

iPTMnetiQ96MZ4.
PhosphoSiteiQ96MZ4.

Expressioni

Gene expression databases

BgeeiQ96MZ4.
CleanExiHS_C4orf39.
GenevisibleiQ96MZ4. HS.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
PSMA3P257883EBI-10291578,EBI-348380

Protein-protein interaction databases

BioGridi127464. 1 interaction.
IntActiQ96MZ4. 1 interaction.
STRINGi9606.ENSP00000427428.

Structurei

3D structure databases

ProteinModelPortaliQ96MZ4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00620000089275.
InParanoidiQ96MZ4.
OMAiGHSKSEG.
OrthoDBiEOG72VH7J.

Sequencei

Sequence statusi: Complete.

Q96MZ4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEGCAVRRGS CPLLPGPSAW RASPAGWAGR AKLRSWCRAS GLPNRPYTLT
60 70 80 90 100
GGRHGSVSLL RHPGTTTFVQ QRSLHQSWEK RIVFSACPVS RSWCPERNFS
110 120 130 140 150
GSIPAVTPPK LPGHSKSEGP PGKVRKRTTI RSQPLFVTRT RGFGSAVGWL

PLGSPVL
Length:157
Mass (Da):17,021
Last modified:December 1, 2001 - v1
Checksum:i7DA9AE4F963BDF56
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti54 – 541H → R.
Corresponds to variant rs3733418 [ dbSNP | Ensembl ].
VAR_044025

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK056221 mRNA. Translation: BAB71123.1.
BC022381 mRNA. Translation: AAH22381.1.
CCDSiCCDS3807.1.
RefSeqiNP_694572.1. NM_153027.1.
UniGeneiHs.178648.

Genome annotation databases

EnsembliENST00000513876; ENSP00000427428; ENSG00000250486.
GeneIDi152756.
KEGGihsa:152756.
UCSCiuc003iqx.2. human.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK056221 mRNA. Translation: BAB71123.1.
BC022381 mRNA. Translation: AAH22381.1.
CCDSiCCDS3807.1.
RefSeqiNP_694572.1. NM_153027.1.
UniGeneiHs.178648.

3D structure databases

ProteinModelPortaliQ96MZ4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi127464. 1 interaction.
IntActiQ96MZ4. 1 interaction.
STRINGi9606.ENSP00000427428.

PTM databases

iPTMnetiQ96MZ4.
PhosphoSiteiQ96MZ4.

Polymorphism and mutation databases

BioMutaiFAM218A.

Proteomic databases

PaxDbiQ96MZ4.
PeptideAtlasiQ96MZ4.
PRIDEiQ96MZ4.

Protocols and materials databases

DNASUi152756.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000513876; ENSP00000427428; ENSG00000250486.
GeneIDi152756.
KEGGihsa:152756.
UCSCiuc003iqx.2. human.

Organism-specific databases

CTDi152756.
GeneCardsiFAM218A.
HGNCiHGNC:26466. FAM218A.
neXtProtiNX_Q96MZ4.
PharmGKBiPA162379827.
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00620000089275.
InParanoidiQ96MZ4.
OMAiGHSKSEG.
OrthoDBiEOG72VH7J.

Miscellaneous databases

GenomeRNAii152756.
PROiQ96MZ4.

Gene expression databases

BgeeiQ96MZ4.
CleanExiHS_C4orf39.
GenevisibleiQ96MZ4. HS.

Family and domain databases

ProtoNetiSearch...

Publicationsi

  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Teratocarcinoma.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Prostate.

Entry informationi

Entry nameiF218A_HUMAN
AccessioniPrimary (citable) accession number: Q96MZ4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: December 1, 2001
Last modified: July 6, 2016
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 4
    Human chromosome 4: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.