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Q96MP5

- ZSWM3_HUMAN

UniProt

Q96MP5 - ZSWM3_HUMAN

Protein

Zinc finger SWIM domain-containing protein 3

Gene

ZSWIM3

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 91 (01 Oct 2014)
      Sequence version 2 (10 Oct 2003)
      Previous versions | rss
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    Functioni

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri531 – 57242SWIM-typePROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. zinc ion binding Source: InterPro

    Keywords - Ligandi

    Metal-binding, Zinc

    Enzyme and pathway databases

    SignaLinkiQ96MP5.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Zinc finger SWIM domain-containing protein 3
    Gene namesi
    Name:ZSWIM3
    Synonyms:C20orf164
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 20

    Organism-specific databases

    HGNCiHGNC:16157. ZSWIM3.

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA25706.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 696696Zinc finger SWIM domain-containing protein 3PRO_0000223099Add
    BLAST

    Proteomic databases

    MaxQBiQ96MP5.
    PaxDbiQ96MP5.
    PRIDEiQ96MP5.

    PTM databases

    PhosphoSiteiQ96MP5.

    Expressioni

    Gene expression databases

    ArrayExpressiQ96MP5.
    BgeeiQ96MP5.
    CleanExiHS_ZSWIM3.
    GenevestigatoriQ96MP5.

    Organism-specific databases

    HPAiHPA055692.

    Interactioni

    Protein-protein interaction databases

    BioGridi126724. 1 interaction.
    IntActiQ96MP5. 1 interaction.

    Structurei

    3D structure databases

    ProteinModelPortaliQ96MP5.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 SWIM-type zinc finger.PROSITE-ProRule annotation

    Zinc finger

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri531 – 57242SWIM-typePROSITE-ProRule annotationAdd
    BLAST

    Keywords - Domaini

    Zinc-finger

    Phylogenomic databases

    eggNOGiNOG40350.
    HOGENOMiHOG000230974.
    HOVERGENiHBG079390.
    InParanoidiQ96MP5.
    KOiK17604.
    OMAiMVCRRWQ.
    OrthoDBiEOG7327NB.
    PhylomeDBiQ96MP5.
    TreeFamiTF335703.

    Family and domain databases

    InterProiIPR018289. MULE_transposase_dom.
    IPR006564. Znf_PMZ.
    IPR007527. Znf_SWIM.
    [Graphical view]
    PfamiPF10551. MULE. 1 hit.
    PF04434. SWIM. 1 hit.
    [Graphical view]
    SMARTiSM00575. ZnF_PMZ. 1 hit.
    [Graphical view]
    PROSITEiPS50966. ZF_SWIM. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q96MP5-1 [UniParc]FASTAAdd to Basket

    « Hide

    MELGSCFKTY EDFKECFSAY KRENRCSFIL RDCVSVRFHN LNHGTSIRED    50
    ILYVQVKFVC IRTQSNRKRT READMCPAYL LLRYNERLDR LFISELNTQH 100
    IHGDSKVASP GGDTTGKSQK TMCLQRLQPV QPTTKKDLDT AEKSLVEPSF 150
    CLDKVQVSSK PEQEGITPSD LAKIAKVMKN FLKVDEGSMA SFSVGDSQHL 200
    DRLSFQSSKM TDLFIRFPEN LLLHRVENTQ GHILYAFLVE NKERESRVVH 250
    FAVLKAETVT SVAKMLSIFT EFNSDWPKVK VVFVDPSFHY RAILQEIFPA 300
    ARILLSIYHT TRLLEKKLHR SSANPSFKRL MKEALREAVF VTSEASLKNL 350
    CQMSQAVLDE DLFNFLQAHW FTCELLWYMH VRKGLLACNT YMDSLDIVTS 400
    KVSSLFREQQ SLLDCILCFV DYIDFFNTKG LKNLPTPPPK LKRARPASMP 450
    LKSKKAFGIC GESLTSLPAE ETKPDAQQVQ VQQQSQVPPS QVGMLDTLHQ 500
    SGSELAYKLC HNEWEVVQNS THLVDMAGSS VDVQLLEDSH QVSKDGCSCS 550
    CSFQQWYHLP CRHILALLHT SQQPVGEAMV CRRWQKKYQY LLGPNGELQD 600
    RGMVPNTGQP EKQGRNDMIQ DLSRELANLL MQTEGPELEE RYSTLRKIVD 650
    IWAGPSQPSE LFQQPGDFKD VGRLPFLWGK QEEGEGFPPA TAVMHY 696
    Length:696
    Mass (Da):79,454
    Last modified:October 10, 2003 - v2
    Checksum:i30C91C23ACB1AF23
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti329 – 3291R → S in BAB71239. (PubMed:14702039)Curated

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti259 – 2591V → A.1 Publication
    Corresponds to variant rs2903808 [ dbSNP | Ensembl ].
    VAR_053769
    Natural varianti291 – 2911R → W.
    Corresponds to variant rs35928298 [ dbSNP | Ensembl ].
    VAR_062161

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK056641 mRNA. Translation: BAB71239.1.
    AL008726 Genomic DNA. Translation: CAC36014.1.
    BC027611 mRNA. Translation: AAH27611.1.
    CCDSiCCDS13381.1.
    RefSeqiNP_542790.2. NM_080752.3.
    UniGeneiHs.292135.

    Genome annotation databases

    EnsembliENST00000255152; ENSP00000255152; ENSG00000132801.
    GeneIDi140831.
    KEGGihsa:140831.
    UCSCiuc002xqd.3. human.

    Polymorphism databases

    DMDMi41019518.

    Keywords - Coding sequence diversityi

    Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK056641 mRNA. Translation: BAB71239.1 .
    AL008726 Genomic DNA. Translation: CAC36014.1 .
    BC027611 mRNA. Translation: AAH27611.1 .
    CCDSi CCDS13381.1.
    RefSeqi NP_542790.2. NM_080752.3.
    UniGenei Hs.292135.

    3D structure databases

    ProteinModelPortali Q96MP5.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 126724. 1 interaction.
    IntActi Q96MP5. 1 interaction.

    PTM databases

    PhosphoSitei Q96MP5.

    Polymorphism databases

    DMDMi 41019518.

    Proteomic databases

    MaxQBi Q96MP5.
    PaxDbi Q96MP5.
    PRIDEi Q96MP5.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000255152 ; ENSP00000255152 ; ENSG00000132801 .
    GeneIDi 140831.
    KEGGi hsa:140831.
    UCSCi uc002xqd.3. human.

    Organism-specific databases

    CTDi 140831.
    GeneCardsi GC20P044486.
    H-InvDB HIX0015866.
    HGNCi HGNC:16157. ZSWIM3.
    HPAi HPA055692.
    neXtProti NX_Q96MP5.
    PharmGKBi PA25706.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG40350.
    HOGENOMi HOG000230974.
    HOVERGENi HBG079390.
    InParanoidi Q96MP5.
    KOi K17604.
    OMAi MVCRRWQ.
    OrthoDBi EOG7327NB.
    PhylomeDBi Q96MP5.
    TreeFami TF335703.

    Enzyme and pathway databases

    SignaLinki Q96MP5.

    Miscellaneous databases

    GenomeRNAii 140831.
    NextBioi 84438.
    PROi Q96MP5.

    Gene expression databases

    ArrayExpressi Q96MP5.
    Bgeei Q96MP5.
    CleanExi HS_ZSWIM3.
    Genevestigatori Q96MP5.

    Family and domain databases

    InterProi IPR018289. MULE_transposase_dom.
    IPR006564. Znf_PMZ.
    IPR007527. Znf_SWIM.
    [Graphical view ]
    Pfami PF10551. MULE. 1 hit.
    PF04434. SWIM. 1 hit.
    [Graphical view ]
    SMARTi SM00575. ZnF_PMZ. 1 hit.
    [Graphical view ]
    PROSITEi PS50966. ZF_SWIM. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANT ALA-259.
      Tissue: Fetal brain.
    2. "The DNA sequence and comparative analysis of human chromosome 20."
      Deloukas P., Matthews L.H., Ashurst J.L., Burton J., Gilbert J.G.R., Jones M., Stavrides G., Almeida J.P., Babbage A.K., Bagguley C.L., Bailey J., Barlow K.F., Bates K.N., Beard L.M., Beare D.M., Beasley O.P., Bird C.P., Blakey S.E.
      , Bridgeman A.M., Brown A.J., Buck D., Burrill W.D., Butler A.P., Carder C., Carter N.P., Chapman J.C., Clamp M., Clark G., Clark L.N., Clark S.Y., Clee C.M., Clegg S., Cobley V.E., Collier R.E., Connor R.E., Corby N.R., Coulson A., Coville G.J., Deadman R., Dhami P.D., Dunn M., Ellington A.G., Frankland J.A., Fraser A., French L., Garner P., Grafham D.V., Griffiths C., Griffiths M.N.D., Gwilliam R., Hall R.E., Hammond S., Harley J.L., Heath P.D., Ho S., Holden J.L., Howden P.J., Huckle E., Hunt A.R., Hunt S.E., Jekosch K., Johnson C.M., Johnson D., Kay M.P., Kimberley A.M., King A., Knights A., Laird G.K., Lawlor S., Lehvaeslaiho M.H., Leversha M.A., Lloyd C., Lloyd D.M., Lovell J.D., Marsh V.L., Martin S.L., McConnachie L.J., McLay K., McMurray A.A., Milne S.A., Mistry D., Moore M.J.F., Mullikin J.C., Nickerson T., Oliver K., Parker A., Patel R., Pearce T.A.V., Peck A.I., Phillimore B.J.C.T., Prathalingam S.R., Plumb R.W., Ramsay H., Rice C.M., Ross M.T., Scott C.E., Sehra H.K., Shownkeen R., Sims S., Skuce C.D., Smith M.L., Soderlund C., Steward C.A., Sulston J.E., Swann R.M., Sycamore N., Taylor R., Tee L., Thomas D.W., Thorpe A., Tracey A., Tromans A.C., Vaudin M., Wall M., Wallis J.M., Whitehead S.L., Whittaker P., Willey D.L., Williams L., Williams S.A., Wilming L., Wray P.W., Hubbard T., Durbin R.M., Bentley D.R., Beck S., Rogers J.
      Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Testis.

    Entry informationi

    Entry nameiZSWM3_HUMAN
    AccessioniPrimary (citable) accession number: Q96MP5
    Secondary accession number(s): Q9BR13
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 10, 2003
    Last sequence update: October 10, 2003
    Last modified: October 1, 2014
    This is version 91 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 20
      Human chromosome 20: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations
    4. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3