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Protein

Zinc finger SWIM domain-containing protein 3

Gene

ZSWIM3

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri531 – 572SWIM-typePROSITE-ProRule annotationAdd BLAST42

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Enzyme and pathway databases

SignaLinkiQ96MP5

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger SWIM domain-containing protein 3
Gene namesi
Name:ZSWIM3
Synonyms:C20orf164
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 20

Organism-specific databases

EuPathDBiHostDB:ENSG00000132801.6
HGNCiHGNC:16157 ZSWIM3
neXtProtiNX_Q96MP5

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000132801
PharmGKBiPA25706

Polymorphism and mutation databases

BioMutaiZSWIM3
DMDMi41019518

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002230991 – 696Zinc finger SWIM domain-containing protein 3Add BLAST696

Proteomic databases

EPDiQ96MP5
MaxQBiQ96MP5
PaxDbiQ96MP5
PeptideAtlasiQ96MP5
PRIDEiQ96MP5
ProteomicsDBi77384

PTM databases

iPTMnetiQ96MP5
PhosphoSitePlusiQ96MP5

Expressioni

Gene expression databases

BgeeiENSG00000132801
CleanExiHS_ZSWIM3
GenevisibleiQ96MP5 HS

Organism-specific databases

HPAiHPA055692
HPA060508

Interactioni

Protein-protein interaction databases

BioGridi126724, 1 interactor
IntActiQ96MP5, 3 interactors

Structurei

3D structure databases

ProteinModelPortaliQ96MP5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri531 – 572SWIM-typePROSITE-ProRule annotationAdd BLAST42

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiENOG410IEGZ Eukaryota
ENOG4110N49 LUCA
GeneTreeiENSGT00390000017273
HOGENOMiHOG000230974
HOVERGENiHBG079390
InParanoidiQ96MP5
KOiK17604
OMAiCPAYLLL
OrthoDBiEOG091G01A2
PhylomeDBiQ96MP5
TreeFamiTF335703

Family and domain databases

InterProiView protein in InterPro
IPR006564 Znf_PMZ
IPR007527 Znf_SWIM
PfamiView protein in Pfam
PF04434 SWIM, 1 hit
SMARTiView protein in SMART
SM00575 ZnF_PMZ, 1 hit
PROSITEiView protein in PROSITE
PS50966 ZF_SWIM, 1 hit

Sequencei

Sequence statusi: Complete.

Q96MP5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MELGSCFKTY EDFKECFSAY KRENRCSFIL RDCVSVRFHN LNHGTSIRED
60 70 80 90 100
ILYVQVKFVC IRTQSNRKRT READMCPAYL LLRYNERLDR LFISELNTQH
110 120 130 140 150
IHGDSKVASP GGDTTGKSQK TMCLQRLQPV QPTTKKDLDT AEKSLVEPSF
160 170 180 190 200
CLDKVQVSSK PEQEGITPSD LAKIAKVMKN FLKVDEGSMA SFSVGDSQHL
210 220 230 240 250
DRLSFQSSKM TDLFIRFPEN LLLHRVENTQ GHILYAFLVE NKERESRVVH
260 270 280 290 300
FAVLKAETVT SVAKMLSIFT EFNSDWPKVK VVFVDPSFHY RAILQEIFPA
310 320 330 340 350
ARILLSIYHT TRLLEKKLHR SSANPSFKRL MKEALREAVF VTSEASLKNL
360 370 380 390 400
CQMSQAVLDE DLFNFLQAHW FTCELLWYMH VRKGLLACNT YMDSLDIVTS
410 420 430 440 450
KVSSLFREQQ SLLDCILCFV DYIDFFNTKG LKNLPTPPPK LKRARPASMP
460 470 480 490 500
LKSKKAFGIC GESLTSLPAE ETKPDAQQVQ VQQQSQVPPS QVGMLDTLHQ
510 520 530 540 550
SGSELAYKLC HNEWEVVQNS THLVDMAGSS VDVQLLEDSH QVSKDGCSCS
560 570 580 590 600
CSFQQWYHLP CRHILALLHT SQQPVGEAMV CRRWQKKYQY LLGPNGELQD
610 620 630 640 650
RGMVPNTGQP EKQGRNDMIQ DLSRELANLL MQTEGPELEE RYSTLRKIVD
660 670 680 690
IWAGPSQPSE LFQQPGDFKD VGRLPFLWGK QEEGEGFPPA TAVMHY
Length:696
Mass (Da):79,454
Last modified:October 10, 2003 - v2
Checksum:i30C91C23ACB1AF23
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti329R → S in BAB71239 (PubMed:14702039).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_053769259V → A1 PublicationCorresponds to variant dbSNP:rs2903808Ensembl.1
Natural variantiVAR_062161291R → W. Corresponds to variant dbSNP:rs35928298Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK056641 mRNA Translation: BAB71239.1
AL008726 Genomic DNA No translation available.
BC027611 mRNA Translation: AAH27611.1
CCDSiCCDS13381.1
RefSeqiNP_542790.2, NM_080752.3
UniGeneiHs.292135

Genome annotation databases

EnsembliENST00000255152; ENSP00000255152; ENSG00000132801
GeneIDi140831
KEGGihsa:140831
UCSCiuc002xqd.4 human

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Entry informationi

Entry nameiZSWM3_HUMAN
AccessioniPrimary (citable) accession number: Q96MP5
Secondary accession number(s): Q9BR13
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 10, 2003
Last sequence update: October 10, 2003
Last modified: June 20, 2018
This is version 110 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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