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Q96MP5

- ZSWM3_HUMAN

UniProt

Q96MP5 - ZSWM3_HUMAN

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Protein

Zinc finger SWIM domain-containing protein 3

Gene
ZSWIM3, C20orf164
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri531 – 57242SWIM-typeAdd
BLAST

GO - Molecular functioni

  1. zinc ion binding Source: InterPro
Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Enzyme and pathway databases

SignaLinkiQ96MP5.

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger SWIM domain-containing protein 3
Gene namesi
Name:ZSWIM3
Synonyms:C20orf164
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 20

Organism-specific databases

HGNCiHGNC:16157. ZSWIM3.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA25706.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 696696Zinc finger SWIM domain-containing protein 3PRO_0000223099Add
BLAST

Proteomic databases

MaxQBiQ96MP5.
PaxDbiQ96MP5.
PRIDEiQ96MP5.

PTM databases

PhosphoSiteiQ96MP5.

Expressioni

Gene expression databases

ArrayExpressiQ96MP5.
BgeeiQ96MP5.
CleanExiHS_ZSWIM3.
GenevestigatoriQ96MP5.

Organism-specific databases

HPAiHPA055692.

Interactioni

Protein-protein interaction databases

BioGridi126724. 1 interaction.
IntActiQ96MP5. 1 interaction.

Structurei

3D structure databases

ProteinModelPortaliQ96MP5.

Family & Domainsi

Sequence similaritiesi

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri531 – 57242SWIM-typeAdd
BLAST

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiNOG40350.
HOGENOMiHOG000230974.
HOVERGENiHBG079390.
InParanoidiQ96MP5.
KOiK17604.
OMAiMVCRRWQ.
OrthoDBiEOG7327NB.
PhylomeDBiQ96MP5.
TreeFamiTF335703.

Family and domain databases

InterProiIPR018289. MULE_transposase_dom.
IPR006564. Znf_PMZ.
IPR007527. Znf_SWIM.
[Graphical view]
PfamiPF10551. MULE. 1 hit.
PF04434. SWIM. 1 hit.
[Graphical view]
SMARTiSM00575. ZnF_PMZ. 1 hit.
[Graphical view]
PROSITEiPS50966. ZF_SWIM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q96MP5-1 [UniParc]FASTAAdd to Basket

« Hide

MELGSCFKTY EDFKECFSAY KRENRCSFIL RDCVSVRFHN LNHGTSIRED    50
ILYVQVKFVC IRTQSNRKRT READMCPAYL LLRYNERLDR LFISELNTQH 100
IHGDSKVASP GGDTTGKSQK TMCLQRLQPV QPTTKKDLDT AEKSLVEPSF 150
CLDKVQVSSK PEQEGITPSD LAKIAKVMKN FLKVDEGSMA SFSVGDSQHL 200
DRLSFQSSKM TDLFIRFPEN LLLHRVENTQ GHILYAFLVE NKERESRVVH 250
FAVLKAETVT SVAKMLSIFT EFNSDWPKVK VVFVDPSFHY RAILQEIFPA 300
ARILLSIYHT TRLLEKKLHR SSANPSFKRL MKEALREAVF VTSEASLKNL 350
CQMSQAVLDE DLFNFLQAHW FTCELLWYMH VRKGLLACNT YMDSLDIVTS 400
KVSSLFREQQ SLLDCILCFV DYIDFFNTKG LKNLPTPPPK LKRARPASMP 450
LKSKKAFGIC GESLTSLPAE ETKPDAQQVQ VQQQSQVPPS QVGMLDTLHQ 500
SGSELAYKLC HNEWEVVQNS THLVDMAGSS VDVQLLEDSH QVSKDGCSCS 550
CSFQQWYHLP CRHILALLHT SQQPVGEAMV CRRWQKKYQY LLGPNGELQD 600
RGMVPNTGQP EKQGRNDMIQ DLSRELANLL MQTEGPELEE RYSTLRKIVD 650
IWAGPSQPSE LFQQPGDFKD VGRLPFLWGK QEEGEGFPPA TAVMHY 696
Length:696
Mass (Da):79,454
Last modified:October 10, 2003 - v2
Checksum:i30C91C23ACB1AF23
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti259 – 2591V → A.1 Publication
Corresponds to variant rs2903808 [ dbSNP | Ensembl ].
VAR_053769
Natural varianti291 – 2911R → W.
Corresponds to variant rs35928298 [ dbSNP | Ensembl ].
VAR_062161

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti329 – 3291R → S in BAB71239. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK056641 mRNA. Translation: BAB71239.1.
AL008726 Genomic DNA. Translation: CAC36014.1.
BC027611 mRNA. Translation: AAH27611.1.
CCDSiCCDS13381.1.
RefSeqiNP_542790.2. NM_080752.3.
UniGeneiHs.292135.

Genome annotation databases

EnsembliENST00000255152; ENSP00000255152; ENSG00000132801.
GeneIDi140831.
KEGGihsa:140831.
UCSCiuc002xqd.3. human.

Polymorphism databases

DMDMi41019518.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK056641 mRNA. Translation: BAB71239.1 .
AL008726 Genomic DNA. Translation: CAC36014.1 .
BC027611 mRNA. Translation: AAH27611.1 .
CCDSi CCDS13381.1.
RefSeqi NP_542790.2. NM_080752.3.
UniGenei Hs.292135.

3D structure databases

ProteinModelPortali Q96MP5.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 126724. 1 interaction.
IntActi Q96MP5. 1 interaction.

PTM databases

PhosphoSitei Q96MP5.

Polymorphism databases

DMDMi 41019518.

Proteomic databases

MaxQBi Q96MP5.
PaxDbi Q96MP5.
PRIDEi Q96MP5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000255152 ; ENSP00000255152 ; ENSG00000132801 .
GeneIDi 140831.
KEGGi hsa:140831.
UCSCi uc002xqd.3. human.

Organism-specific databases

CTDi 140831.
GeneCardsi GC20P044486.
H-InvDB HIX0015866.
HGNCi HGNC:16157. ZSWIM3.
HPAi HPA055692.
neXtProti NX_Q96MP5.
PharmGKBi PA25706.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG40350.
HOGENOMi HOG000230974.
HOVERGENi HBG079390.
InParanoidi Q96MP5.
KOi K17604.
OMAi MVCRRWQ.
OrthoDBi EOG7327NB.
PhylomeDBi Q96MP5.
TreeFami TF335703.

Enzyme and pathway databases

SignaLinki Q96MP5.

Miscellaneous databases

GenomeRNAii 140831.
NextBioi 84438.
PROi Q96MP5.

Gene expression databases

ArrayExpressi Q96MP5.
Bgeei Q96MP5.
CleanExi HS_ZSWIM3.
Genevestigatori Q96MP5.

Family and domain databases

InterProi IPR018289. MULE_transposase_dom.
IPR006564. Znf_PMZ.
IPR007527. Znf_SWIM.
[Graphical view ]
Pfami PF10551. MULE. 1 hit.
PF04434. SWIM. 1 hit.
[Graphical view ]
SMARTi SM00575. ZnF_PMZ. 1 hit.
[Graphical view ]
PROSITEi PS50966. ZF_SWIM. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANT ALA-259.
    Tissue: Fetal brain.
  2. "The DNA sequence and comparative analysis of human chromosome 20."
    Deloukas P., Matthews L.H., Ashurst J.L., Burton J., Gilbert J.G.R., Jones M., Stavrides G., Almeida J.P., Babbage A.K., Bagguley C.L., Bailey J., Barlow K.F., Bates K.N., Beard L.M., Beare D.M., Beasley O.P., Bird C.P., Blakey S.E.
    , Bridgeman A.M., Brown A.J., Buck D., Burrill W.D., Butler A.P., Carder C., Carter N.P., Chapman J.C., Clamp M., Clark G., Clark L.N., Clark S.Y., Clee C.M., Clegg S., Cobley V.E., Collier R.E., Connor R.E., Corby N.R., Coulson A., Coville G.J., Deadman R., Dhami P.D., Dunn M., Ellington A.G., Frankland J.A., Fraser A., French L., Garner P., Grafham D.V., Griffiths C., Griffiths M.N.D., Gwilliam R., Hall R.E., Hammond S., Harley J.L., Heath P.D., Ho S., Holden J.L., Howden P.J., Huckle E., Hunt A.R., Hunt S.E., Jekosch K., Johnson C.M., Johnson D., Kay M.P., Kimberley A.M., King A., Knights A., Laird G.K., Lawlor S., Lehvaeslaiho M.H., Leversha M.A., Lloyd C., Lloyd D.M., Lovell J.D., Marsh V.L., Martin S.L., McConnachie L.J., McLay K., McMurray A.A., Milne S.A., Mistry D., Moore M.J.F., Mullikin J.C., Nickerson T., Oliver K., Parker A., Patel R., Pearce T.A.V., Peck A.I., Phillimore B.J.C.T., Prathalingam S.R., Plumb R.W., Ramsay H., Rice C.M., Ross M.T., Scott C.E., Sehra H.K., Shownkeen R., Sims S., Skuce C.D., Smith M.L., Soderlund C., Steward C.A., Sulston J.E., Swann R.M., Sycamore N., Taylor R., Tee L., Thomas D.W., Thorpe A., Tracey A., Tromans A.C., Vaudin M., Wall M., Wallis J.M., Whitehead S.L., Whittaker P., Willey D.L., Williams L., Williams S.A., Wilming L., Wray P.W., Hubbard T., Durbin R.M., Bentley D.R., Beck S., Rogers J.
    Nature 414:865-871(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Testis.

Entry informationi

Entry nameiZSWM3_HUMAN
AccessioniPrimary (citable) accession number: Q96MP5
Secondary accession number(s): Q9BR13
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 10, 2003
Last sequence update: October 10, 2003
Last modified: July 9, 2014
This is version 90 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 20
    Human chromosome 20: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  4. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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