Q96MF8 (Q96MF8_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Nebulin Ensembl ENSP00000380497

Submitted name:
cDNA FLJ32432 fis, clone SKMUS2001157, highly similar to Homo sapiens nebulin (NEB) gene EMBL BAB71337.1

Gene names

Name:

NEB Ensembl ENSP00000380497

Organism

Homo sapiens (Human) [Reference proteome] EMBL BAB71337.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	500 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 SH3 domain. RuleBase RU003338

Ontologies

Keywords
Domain	SH3 domain RuleBase RU003338
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
None. [Check GOA]

Sequences

	Sequence		Length	Mass (Da)
	Q96MF8 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: 231C7CBC39B60EF5	FASTA	500	56,781
	10 20 30 40 50 60 MERVKRNQEN FSSVLYKENL GTGIPIPITP EMQRVKHNQE NLSSVLYKEN MGKGTPLPVT 70 80 90 100 110 120 PEMERVKHNQ ENISSVLYKE NMGKGTPLPV TPEMERVKHN QENISSVLYK ENMGKGTPLA 130 140 150 160 170 180 VTPEMERVKH NQENISSVLY KENVGKATAT PVTPEMQRVK RNQENISSVL YKENLGKATP 190 200 210 220 230 240 TPFTPEMERV KRNQENFSSV LYKENMRKAT PTPVTPEMER AKRNQENISS VLYSDSFRKQ 250 260 270 280 290 300 IQGKAAYVLD TPEMRRVRET QRHISTVKYH EDFEKHKGCF TPVVTDPITE RVKKNMQDFS 310 320 330 340 350 360 DINYRGIQRK VVEMEQKRND QDQETITGLR VWRTNPGSVF DYDPAEDNIQ SRSLHMINVQ 370 380 390 400 410 420 AQRRSREQSR SASALSISGG EEKSEHSEAP DHHLSTYSDG GVFAVSTAYK HAKTTELPQQ 430 440 450 460 470 480 RSSSVATQQT TVSSIPSHPS TAGKIFRAMY DYMAADADEV SFKDGDAIIN VQAIDEGWMY 490 500 GTVQRTGRTG MLPANYVEAI

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Tissue: Skeletal muscle EMBL BAB71337.1.
[2]	"Generation and annotation of the DNA sequences of human chromosomes 2 and 4." Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H. , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K. Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[3]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC009497 Genomic DNA. No translation available. AC107052 Genomic DNA. No translation available. AC116650 Genomic DNA. No translation available. AK056994 mRNA. Translation: BAB71337.1.
IPI	IPI00873952.
RefSeq	NP_004534.2. NM_004543.4.
UniGene	Hs.588655.
3D structure databases
HSSP	HSSP built from PDB template 1ARK based on UniProtKB P20929.
SMR	Q96MF8. Positions 441-500.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000397336; ENSP00000380497; ENSG00000183091.
GeneID	4703.
KEGG	hsa:4703.
Organism-specific databases
CTD	4703.
HGNC	HGNC:7720. NEB.
PharmGKB	PA31530.
GenAtlas	Search...
Phylogenomic databases
HOGENOM	HOG000015358.
HOVERGEN	HBG074990.
Gene expression databases
ArrayExpress	Q96MF8.
Family and domain databases
InterPro	IPR000900. Nebulin_35r-motif. IPR001452. SH3_domain. [Graphical view]
Pfam	PF00880. Nebulin. 8 hits. PF00018. SH3_1. 1 hit. [Graphical view]
PRINTS	PR00452. SH3DOMAIN.
SMART	SM00227. NEBU. 10 hits. SM00326. SH3. 1 hit. [Graphical view]
SUPFAM	SSF50044. SH3. 1 hit.
PROSITE	PS51216. NEBULIN. 10 hits. PS50002. SH3. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	NEB. human.
GenomeRNAi	4703.
NextBio	18136.

Entry information

Entry name

Q96MF8_HUMAN

Accession

Primary (citable) accession number: Q96MF8
Secondary accession number(s): A8MX54

Entry history

Integrated into UniProtKB/TrEMBL:	December 1, 2001
Last sequence update:	December 1, 2001
Last modified:	May 1, 2013
This is version 83 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.