ID   CCDC7_HUMAN             Reviewed;        1385 AA.
AC   Q96M83; B0QZ71; Q08AN7; Q5VW55; Q8IVQ0; Q8N7T7; Q8NEQ0; Q9H943;
DT   07-JUN-2004, integrated into UniProtKB/Swiss-Prot.
DT   08-JUN-2016, sequence version 3.
DT   27-MAR-2024, entry version 150.
DE   RecName: Full=Coiled-coil domain-containing protein 7;
DE   AltName: Full=Protein BIOT2;
GN   Name=CCDC7; Synonyms=BIOT2, C10orf68;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2), NUCLEOTIDE SEQUENCE
RP   [LARGE SCALE MRNA] OF 418-1385 (ISOFORM 4), NUCLEOTIDE SEQUENCE [LARGE
RP   SCALE MRNA] OF 887-1385 (ISOFORM 1), AND VARIANTS ALA-1117 AND ILE-1364.
RC   TISSUE=Teratocarcinoma, and Testis;
RX   PubMed=14702039; DOI=10.1038/ng1285;
RA   Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA   Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA   Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA   Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA   Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H.,
RA   Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M.,
RA   Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K.,
RA   Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T.,
RA   Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M.,
RA   Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S.,
RA   Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H.,
RA   Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K.,
RA   Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N.,
RA   Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA   Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA   Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA   Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA   Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y.,
RA   Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K.,
RA   Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T.,
RA   Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T.,
RA   Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y.,
RA   Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H.,
RA   Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y.,
RA   Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H.,
RA   Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O.,
RA   Isogai T., Sugano S.;
RT   "Complete sequencing and characterization of 21,243 full-length human
RT   cDNAs.";
RL   Nat. Genet. 36:40-45(2004).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15164054; DOI=10.1038/nature02462;
RA   Deloukas P., Earthrowl M.E., Grafham D.V., Rubenfield M., French L.,
RA   Steward C.A., Sims S.K., Jones M.C., Searle S., Scott C., Howe K.,
RA   Hunt S.E., Andrews T.D., Gilbert J.G.R., Swarbreck D., Ashurst J.L.,
RA   Taylor A., Battles J., Bird C.P., Ainscough R., Almeida J.P.,
RA   Ashwell R.I.S., Ambrose K.D., Babbage A.K., Bagguley C.L., Bailey J.,
RA   Banerjee R., Bates K., Beasley H., Bray-Allen S., Brown A.J., Brown J.Y.,
RA   Burford D.C., Burrill W., Burton J., Cahill P., Camire D., Carter N.P.,
RA   Chapman J.C., Clark S.Y., Clarke G., Clee C.M., Clegg S., Corby N.,
RA   Coulson A., Dhami P., Dutta I., Dunn M., Faulkner L., Frankish A.,
RA   Frankland J.A., Garner P., Garnett J., Gribble S., Griffiths C.,
RA   Grocock R., Gustafson E., Hammond S., Harley J.L., Hart E., Heath P.D.,
RA   Ho T.P., Hopkins B., Horne J., Howden P.J., Huckle E., Hynds C.,
RA   Johnson C., Johnson D., Kana A., Kay M., Kimberley A.M., Kershaw J.K.,
RA   Kokkinaki M., Laird G.K., Lawlor S., Lee H.M., Leongamornlert D.A.,
RA   Laird G., Lloyd C., Lloyd D.M., Loveland J., Lovell J., McLaren S.,
RA   McLay K.E., McMurray A., Mashreghi-Mohammadi M., Matthews L., Milne S.,
RA   Nickerson T., Nguyen M., Overton-Larty E., Palmer S.A., Pearce A.V.,
RA   Peck A.I., Pelan S., Phillimore B., Porter K., Rice C.M., Rogosin A.,
RA   Ross M.T., Sarafidou T., Sehra H.K., Shownkeen R., Skuce C.D., Smith M.,
RA   Standring L., Sycamore N., Tester J., Thorpe A., Torcasso W., Tracey A.,
RA   Tromans A., Tsolas J., Wall M., Walsh J., Wang H., Weinstock K., West A.P.,
RA   Willey D.L., Whitehead S.L., Wilming L., Wray P.W., Young L., Chen Y.,
RA   Lovering R.C., Moschonas N.K., Siebert R., Fechtel K., Bentley D.,
RA   Durbin R.M., Hubbard T., Doucette-Stamm L., Beck S., Smith D.R., Rogers J.;
RT   "The DNA sequence and comparative analysis of human chromosome 10.";
RL   Nature 429:375-381(2004).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M.,
RA   Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J.,
RA   Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S.,
RA   Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H.,
RA   Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K.,
RA   Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D.,
RA   Hunkapiller M.W., Myers E.W., Venter J.C.;
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3), AND NUCLEOTIDE SEQUENCE
RP   [LARGE SCALE MRNA] OF 456-1385 (ISOFORM 5).
RC   TISSUE=Brain, and Testis;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [5]
RP   TISSUE SPECIFICITY.
RX   PubMed=21109960;
RA   Shen Y.M., He X., Deng H.X., Xie Y.P., Wang C.T., Wei Y.Q., Zhao X.;
RT   "Overexpression of the hBiot2 gene is associated with development of human
RT   cervical cancer.";
RL   Oncol. Rep. 25:75-80(2011).
CC   -!- FUNCTION: May play a role in tumorigenesis.
CC       {ECO:0000250|UniProtKB:Q9D541}.
CC   -!- INTERACTION:
CC       Q96M83-3; P42858: HTT; NbExp=18; IntAct=EBI-18211613, EBI-466029;
CC       Q96M83-3; Q9UBU9: NXF1; NbExp=3; IntAct=EBI-18211613, EBI-398874;
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=5;
CC       Name=1;
CC         IsoId=Q96M83-1; Sequence=Displayed;
CC       Name=2;
CC         IsoId=Q96M83-2; Sequence=VSP_010525, VSP_010526;
CC       Name=3;
CC         IsoId=Q96M83-3; Sequence=VSP_058369, VSP_058370;
CC       Name=4;
CC         IsoId=Q96M83-4; Sequence=VSP_058367, VSP_058368;
CC       Name=5;
CC         IsoId=Q96M83-5; Sequence=VSP_058366, VSP_058371;
CC   -!- TISSUE SPECIFICITY: Expressed in epithelium of normal cervix and
CC       cervical cancer. Overexpressed in early and interim cervical cancer.
CC       {ECO:0000269|PubMed:21109960}.
CC   -!- MISCELLANEOUS: [Isoform 2]: May be produced at very low levels due to a
CC       premature stop codon in the mRNA, leading to nonsense-mediated mRNA
CC       decay. {ECO:0000305}.
CC   -!- MISCELLANEOUS: [Isoform 4]: May be produced at very low levels due to a
CC       premature stop codon in the mRNA, leading to nonsense-mediated mRNA
CC       decay. {ECO:0000305}.
CC   -!- MISCELLANEOUS: [Isoform 5]: May be produced at very low levels due to a
CC       premature stop codon in the mRNA, leading to nonsense-mediated mRNA
CC       decay. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAI25092.1; Type=Erroneous translation; Note=Wrong choice of frame.; Evidence={ECO:0000305};
CC       Sequence=BAB14400.1; Type=Erroneous translation; Note=Wrong choice of frame.; Evidence={ECO:0000305};
CC       Sequence=BAC05140.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AK023093; BAB14400.1; ALT_SEQ; mRNA.
DR   EMBL; AK057324; BAB71426.1; -; mRNA.
DR   EMBL; AK097668; BAC05140.1; ALT_INIT; mRNA.
DR   EMBL; AL354750; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AL356053; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AL365203; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AL391839; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AL591850; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; CH471072; EAW85966.1; -; Genomic_DNA.
DR   EMBL; BC022020; AAH22020.2; -; mRNA.
DR   EMBL; BC042672; AAH42672.1; -; mRNA.
DR   EMBL; BC125091; AAI25092.1; ALT_SEQ; mRNA.
DR   CCDS; CCDS7173.1; -. [Q96M83-3]
DR   CCDS; CCDS86081.1; -. [Q96M83-1]
DR   RefSeq; NP_001021554.1; NM_001026383.2. [Q96M83-3]
DR   RefSeq; NP_001308044.1; NM_001321115.1. [Q96M83-1]
DR   RefSeq; NP_659460.3; NM_145023.5. [Q96M83-3]
DR   RefSeq; XP_011517965.1; XM_011519663.1.
DR   AlphaFoldDB; Q96M83; -.
DR   SMR; Q96M83; -.
DR   BioGRID; 122854; 14.
DR   IntAct; Q96M83; 9.
DR   STRING; 9606.ENSP00000491655; -.
DR   GlyGen; Q96M83; 1 site, 1 O-linked glycan (1 site).
DR   iPTMnet; Q96M83; -.
DR   PhosphoSitePlus; Q96M83; -.
DR   BioMuta; CCDC7; -.
DR   DMDM; 48428133; -.
DR   jPOST; Q96M83; -.
DR   MassIVE; Q96M83; -.
DR   MaxQB; Q96M83; -.
DR   PaxDb; 9606-ENSP00000355078; -.
DR   PeptideAtlas; Q96M83; -.
DR   ProteomicsDB; 77306; -. [Q96M83-1]
DR   ProteomicsDB; 77307; -. [Q96M83-2]
DR   ProteomicsDB; 81280; -.
DR   ProteomicsDB; 81281; -.
DR   ProteomicsDB; 81282; -.
DR   Antibodypedia; 80107; 84 antibodies from 21 providers.
DR   DNASU; 221016; -.
DR   Ensembl; ENST00000277657.12; ENSP00000277657.6; ENSG00000216937.14. [Q96M83-3]
DR   Ensembl; ENST00000362006.11; ENSP00000355078.5; ENSG00000216937.14. [Q96M83-3]
DR   Ensembl; ENST00000476558.7; ENSP00000436435.3; ENSG00000216937.14. [Q96M83-2]
DR   Ensembl; ENST00000639629.2; ENSP00000491655.1; ENSG00000216937.14. [Q96M83-1]
DR   GeneID; 79741; -.
DR   KEGG; hsa:79741; -.
DR   MANE-Select; ENST00000639629.2; ENSP00000491655.1; NM_001395015.1; NP_001381944.1.
DR   UCSC; uc001iwj.5; human. [Q96M83-1]
DR   AGR; HGNC:26533; -.
DR   DisGeNET; 79741; -.
DR   GeneCards; CCDC7; -.
DR   HGNC; HGNC:26533; CCDC7.
DR   HPA; ENSG00000216937; Tissue enriched (testis).
DR   MIM; 619444; gene.
DR   neXtProt; NX_Q96M83; -.
DR   OpenTargets; ENSG00000216937; -.
DR   PharmGKB; PA134879457; -.
DR   VEuPathDB; HostDB:ENSG00000216937; -.
DR   eggNOG; ENOG502S48H; Eukaryota.
DR   GeneTree; ENSGT00940000164808; -.
DR   HOGENOM; CLU_1036434_0_0_1; -.
DR   InParanoid; Q96M83; -.
DR   OMA; TRNESFH; -.
DR   OrthoDB; 4340199at2759; -.
DR   TreeFam; TF337205; -.
DR   TreeFam; TF351892; -.
DR   PathwayCommons; Q96M83; -.
DR   SignaLink; Q96M83; -.
DR   BioGRID-ORCS; 79741; 20 hits in 1150 CRISPR screens.
DR   ChiTaRS; CCDC7; human.
DR   GenomeRNAi; 79741; -.
DR   Pharos; Q96M83; Tbio.
DR   PRO; PR:Q96M83; -.
DR   Proteomes; UP000005640; Chromosome 10.
DR   RNAct; Q96M83; Protein.
DR   Bgee; ENSG00000216937; Expressed in calcaneal tendon and 124 other cell types or tissues.
DR   ExpressionAtlas; Q96M83; baseline and differential.
DR   InterPro; IPR029272; CCDC7.
DR   PANTHER; PTHR22035; COILED-COIL DOMAIN-CONTAINING PROTEIN 7; 1.
DR   PANTHER; PTHR22035:SF4; COILED-COIL DOMAIN-CONTAINING PROTEIN 7; 1.
DR   Pfam; PF15368; BioT2; 1.
DR   Genevisible; Q96M83; HS.
PE   1: Evidence at protein level;
KW   Alternative splicing; Coiled coil; Reference proteome.
FT   CHAIN           1..1385
FT                   /note="Coiled-coil domain-containing protein 7"
FT                   /id="PRO_0000089399"
FT   REGION          329..364
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          422..545
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          572..752
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          809..834
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          299..330
FT                   /evidence="ECO:0000255"
FT   COILED          374..411
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        349..364
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        423..440
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        441..456
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        457..481
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        492..545
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        664..699
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        714..734
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        809..830
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   VAR_SEQ         267
FT                   /note="T -> L (in isoform 2)"
FT                   /evidence="ECO:0000303|PubMed:14702039"
FT                   /id="VSP_010525"
FT   VAR_SEQ         268..1385
FT                   /note="Missing (in isoform 2)"
FT                   /evidence="ECO:0000303|PubMed:14702039"
FT                   /id="VSP_010526"
FT   VAR_SEQ         474..516
FT                   /note="ITAQSGRLIEKSSEKKRSSPAISDLSQILKSQDESAFLESSNE -> AVQET
FT                   WCRHLLLARASGSFYSCRKVKWEQICHTLIMKYQMKGL (in isoform 5)"
FT                   /id="VSP_058366"
FT   VAR_SEQ         474..479
FT                   /note="ITAQSG -> LREETI (in isoform 4)"
FT                   /id="VSP_058367"
FT   VAR_SEQ         480..1385
FT                   /note="Missing (in isoform 4)"
FT                   /id="VSP_058368"
FT   VAR_SEQ         485..486
FT                   /note="SS -> RC (in isoform 3)"
FT                   /id="VSP_058369"
FT   VAR_SEQ         487..1385
FT                   /note="Missing (in isoform 3)"
FT                   /id="VSP_058370"
FT   VAR_SEQ         517..1385
FT                   /note="Missing (in isoform 5)"
FT                   /id="VSP_058371"
FT   VARIANT         148
FT                   /note="K -> Q (in dbSNP:rs56391924)"
FT                   /id="VAR_061586"
FT   VARIANT         449
FT                   /note="K -> T (in dbSNP:rs12268559)"
FT                   /id="VAR_050766"
FT   VARIANT         1117
FT                   /note="G -> A (in dbSNP:rs4448627)"
FT                   /evidence="ECO:0000269|PubMed:14702039"
FT                   /id="VAR_033692"
FT   VARIANT         1267
FT                   /note="M -> T (in dbSNP:rs2504011)"
FT                   /id="VAR_024308"
FT   VARIANT         1364
FT                   /note="V -> I (in dbSNP:rs1418538)"
FT                   /evidence="ECO:0000269|PubMed:14702039"
FT                   /id="VAR_033693"
FT   CONFLICT        1055
FT                   /note="R -> Q (in Ref. 1; BAC05140)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        1287
FT                   /note="T -> A (in Ref. 1; BAC05140)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   1385 AA;  157448 MW;  90D132BC39C458C7 CRC64;
     MKPVKHLLTT SNKSANVPAL TTKKGLHNLP LSPELKEKHN AKLIHDKIEP MVLRSPPTGE
     SILRYALPIP SSKTKNLLPE DEMIGKIIKH LKMVVSTLEE TYGHCDQNGE EPFVKHEHEE
     LSLSVGDDMN SFLTYCSQFA AQLEEALKEE QNILESLFKW FQWQVNQMEE ISKDQTLLQA
     EPPKPDKTVI LNIAEIVRLV QRFEELKNRL KQRSKSSVKV MLSKTMDKEN RPEAVKSCEA
     LAQKIEEFLE AHSTDEFKDV SATEPQTAHS MTNRFNAMLK VFENQANMLE RAVNDQVLLD
     AEYKQMQCDF QLLSEEKLVL ENELQKLKDK EKTKPTNNRT KKAVKTVKKK DKGKSEDSEK
     KMSPEKEFKI KEDLDQVQKV ARLEIENKVL QEQLKQALQE AEKAKHQLNY FLNQEKLLKS
     EGKTETTMQV GNSQTKVKGE DSKNIPLEKE TRKSLVSDSG GQRTSDKIQE YPQITAQSGR
     LIEKSSEKKR SSPAISDLSQ ILKSQDESAF LESSNEVSVA ENQSYKSPSE THDKSLTTVS
     SSKEVQDSLS VGTLAQKNET VISPFILPPV LTESKKADVS EEQLQKMTEE QTYQAAEKSQ
     ADSEVPDENL MVENKDSVTK VQIEQMKQRT SSMERHEETL TTPQLPEDMV LVSRIQSETK
     NLKATRNESF HSHNDVPEEN LMLEQDTKSK TEVEVKKQKS FQDNQLSTHN EVPNERLVVE
     HQESLSKTKL QIKKQETSTE QPLTTPDKEP NENLILRHQD SMSKSEMQVK EQRTLKGQRI
     ITHDEEPGKN LVLEHQDSVS KLEMQIEKTK KLPREKRHST HDEESGENPM LKHQDSVSKI
     QVQLEIQETS EGEGRSIPDK NSMFVHQDSV SKLQMQEKKK ITPGRERRNT RIVVPNENVI
     SVHQDSKSKL QMQEKKQINS GVERHKTFPL EIKKKDISLE HLLPEEKVLL SRSESQTKKL
     QAKVTSRKIK NEAASELPDT AENLPAMYPS ISDLIIQFDL NKVVETDIES LRGALGRRLL
     NDEFKTQSKS FPGPDIEQLT DAFGRDILKD EFKTRSKSLP ETDERLHSTT ERGTINDAIK
     TQLKRKSYPE TVLKHLKGVN GKDIIKHLIN IQSKSHGETD KEHLADDTGR GIIKGSINAQ
     LKGHQKTDKN FFAYATGRGL MKESTTTQLK SHPETDKEFL ADAIGRGIII GPITTQLKSH
     RETDKELLKD AIGRDIIKGP ISAQLKSHQE TDVEPLTNAI GSSKTIGEIK TQLRTHYDVN
     LFKNKDMSVQ RQEGIFTRSI TPSKFPTKVI NLSPFENKEE TYEYSSPYVT APSKAIYRTY
     RAGPSFSKDI HLPLLNQLPS GHSKVVTLSQ KTIEFTLPTV TNTVGKPTYK VLHAAARKSV
     PHPYF
//