Reviewed, UniProtKB/Swiss-Prot Q96M20 (CT152_HUMAN)

Names and origin

Protein names

Recommended name:
    Uncharacterized protein C20orf152

Gene names

Name:

C20orf152

Organism

Homo sapiens (Human) [Complete proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	576 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Contains 1 cyclic nucleotide-binding domain.

Ontologies

Keywords
Coding sequence diversity	Polymorphism
Technical term	Complete proteome
Gene Ontology (GO)
None. [Check GOA]

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 576	576	Uncharacterized protein C20orf152		PRO_0000079471
Regions
	Nucleotide binding	116 – 239	124	cNMP
Natural variations
	Natural variant	37	1	R → H: dbSNP rs17347958.		VAR_056853
	Natural variant	208	1	T → A: dbSNP rs6142471.		VAR_056854
	Natural variant	375	1	P → S: dbSNP rs6060750. Ref.1		VAR_056855
Experimental info
	Sequence conflict	424 – 427	4	Missing in BAB71494. Ref.1

Sequences

	Sequence		Length	Mass (Da)
	Q96M20-1 [UniParc]. Last modified November 15, 2002. Version 2. Checksum: B38592A8233A9354	FASTA	576	67,512
	10 20 30 40 50 60 MRRHMVTYAW QLLKKELGLY QLAMDIIIMI RVCKMFRQGL RGFREYQIIE TAHWKHPIFS 70 80 90 100 110 120 FWDKKMQSRV TFDTMDFIAE EGHFPPKAIQ IMQKKPSWRT EDEIQAVCNI LQVLDSYRNY 130 140 150 160 170 180 AEPLQLLLAK VMRFERFGRR RVIIKKGQKG NSFYFIYLGT VAITKDEDGS SAFLDPHPKL 190 200 210 220 230 240 LHKGSCFGEM DVLHASVRRS TIVCMEETEF LVVDREDFFA NKLDQEVQKD AQYRFEFFRK 250 260 270 280 290 300 MELFASWSDE KLWQLVAMAK IERFSYGQLI SKDFGESPFI MFISKGSCEV LRLLDLGASP 310 320 330 340 350 360 SYRRWIWQHL ELIDGRPLKT HLSEYSPMER FKEFQIKSYP LQDFSSLKLP HLKKAWGLQG 370 380 390 400 410 420 TSFSRKIRTS GDTLPKMLGP KIQSRPAQSI KCAMINIKPG ELPKEAAVGA YVKVHTVEQG 430 440 450 460 470 480 EILGLHQAFL PEGECDTRPL ILMSLGNELI RIRKEIFYEL IDNDDEMIKK LLKLNIAFPS 490 500 510 520 530 540 DEDMCQKFLQ QNSWNIFRKD LLQLLVEPCQ SQLFTPNRPK KREIYNPKSV VLDLCSINKT 550 560 570 TKPRYPIFMA PQKYLPPLRI VQAIKAPRYK IRELLA

References

[1]

"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed: 14702039] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANT SER-375. Tissue: Testis.

[2]

"The DNA sequence and comparative analysis of human chromosome 20." Deloukas P., Matthews L.H., Ashurst J.L., Burton J., Gilbert J.G.R., Jones M., Stavrides G., Almeida J.P., Babbage A.K., Bagguley C.L., Bailey J., Barlow K.F., Bates K.N., Beard L.M., Beare D.M., Beasley O.P., Bird C.P., Blakey S.E. , Bridgeman A.M., Brown A.J., Buck D., Burrill W.D., Butler A.P., Carder C., Carter N.P., Chapman J.C., Clamp M., Clark G., Clark L.N., Clark S.Y., Clee C.M., Clegg S., Cobley V.E., Collier R.E., Connor R.E., Corby N.R., Coulson A., Coville G.J., Deadman R., Dhami P.D., Dunn M., Ellington A.G., Frankland J.A., Fraser A., French L., Garner P., Grafham D.V., Griffiths C., Griffiths M.N.D., Gwilliam R., Hall R.E., Hammond S., Harley J.L., Heath P.D., Ho S., Holden J.L., Howden P.J., Huckle E., Hunt A.R., Hunt S.E., Jekosch K., Johnson C.M., Johnson D., Kay M.P., Kimberley A.M., King A., Knights A., Laird G.K., Lawlor S., Lehvaeslaiho M.H., Leversha M.A., Lloyd C., Lloyd D.M., Lovell J.D., Marsh V.L., Martin S.L., McConnachie L.J., McLay K., McMurray A.A., Milne S.A., Mistry D., Moore M.J.F., Mullikin J.C., Nickerson T., Oliver K., Parker A., Patel R., Pearce T.A.V., Peck A.I., Phillimore B.J.C.T., Prathalingam S.R., Plumb R.W., Ramsay H., Rice C.M., Ross M.T., Scott C.E., Sehra H.K., Shownkeen R., Sims S., Skuce C.D., Smith M.L., Soderlund C., Steward C.A., Sulston J.E., Swann R.M., Sycamore N., Taylor R., Tee L., Thomas D.W., Thorpe A., Tracey A., Tromans A.C., Vaudin M., Wall M., Wallis J.M., Whitehead S.L., Whittaker P., Willey D.L., Williams L., Williams S.A., Wilming L., Wray P.W., Hubbard T., Durbin R.M., Bentley D.R., Beck S., Rogers J. Nature 414:865-871(2001) [PubMed: 11780052] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	AK057454 mRNA. Translation: BAB71494.1. AL109965, AL359828 Genomic DNA. Translation: CAI19248.1. AL359828, AL109965 Genomic DNA. Translation: CAI23441.1.
IPI	IPI00097257.
RefSeq	NP_543024.1.
UniGene	Hs.517008
3D structure databases
ModBase	Search...
PTM databases
PhosphoSite	Q96M20.
Proteomic databases
PRIDE	Q96M20.
Genome annotation databases
Ensembl	ENST00000373973; ENSP00000363084; ENSG00000149646; Homo sapiens. [Genome view]
GeneID	140894.
KEGG	hsa:140894.
Organism-specific databases
CTD	140894.
GeneCards	GC20P034019.
HGNC	HGNC:16145. C20orf152.
PharmGKB	PA25694.
GenAtlas	Search...
Phylogenomic databases
HOGENOM	Q96M20.
HOVERGEN	Q96M20.
OMA	YPLQDFS
Gene expression databases
ArrayExpress	Q96M20.
Bgee	Q96M20.
CleanEx	HS_C20orf152.
Genevestigator	Q96M20.
GermOnline	ENSG00000149646. Homo sapiens.
Family and domain databases
InterPro	IPR000595. cNMP_bd. IPR018490. cNMP_bd-like. IPR018488. cNMP_bd_CS. IPR014710. RmlC-like_jellyroll. [Graphical view]
Gene3D	G3DSA:2.60.120.10. RmlC-like_jellyroll. 1 hit.
Pfam	PF00027. cNMP_binding. 1 hit. [Graphical view]
SMART	SM00100. cNMP. 1 hit. [Graphical view]
PROSITE	PS00888. CNMP_BINDING_1. 1 hit. PS00889. CNMP_BINDING_2. False negative. PS50042. CNMP_BINDING_3. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	84559.

Entry information

Entry name

CT152_HUMAN

Accession

Primary (citable) accession number: Q96M20
Secondary accession number(s): Q5T3S1, Q9BR36, Q9BWY5

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 15, 2002
Last sequence update:	November 15, 2002
Last modified:	November 24, 2009
This is version 59 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.