Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Testis-expressed sequence 37 protein

Gene

TEX37

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Testis-expressed sequence 37 protein
Alternative name(s):
Testis-specific conserved protein of 21 kDa
Gene namesi
Name:TEX37
Synonyms:C2orf51, TSC21
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

HGNCiHGNC:26341. TEX37.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: UniProtKB
  • nucleus Source: UniProtKB-SubCell

Keywords - Cellular componenti

Cytoplasm, Nucleus

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000172073.
PharmGKBiPA162379191.

Polymorphism and mutation databases

BioMutaiTEX37.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003049891 – 180Testis-expressed sequence 37 proteinAdd BLAST180

Proteomic databases

PaxDbiQ96LM6.
PeptideAtlasiQ96LM6.
PRIDEiQ96LM6.

PTM databases

iPTMnetiQ96LM6.
PhosphoSitePlusiQ96LM6.

Expressioni

Tissue specificityi

Testis-specific (PubMed:17091336, PubMed:26168773). Detected in the germ cell lineage at all stages (PubMed:26168773).2 Publications

Gene expression databases

BgeeiENSG00000172073.
CleanExiHS_C2orf51.
ExpressionAtlasiQ96LM6. baseline and differential.
GenevisibleiQ96LM6. HS.

Organism-specific databases

HPAiHPA043987.

Interactioni

Binary interactionsi

Show more details

Protein-protein interaction databases

BioGridi128332. 6 interactors.
IntActiQ96LM6. 42 interactors.
MINTiMINT-1456070.
STRINGi9606.ENSP00000307142.

Structurei

3D structure databases

ProteinModelPortaliQ96LM6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410J9TU. Eukaryota.
ENOG411193C. LUCA.
GeneTreeiENSGT00390000012177.
HOGENOMiHOG000154692.
HOVERGENiHBG108602.
InParanoidiQ96LM6.
OMAiYLLLPGC.
OrthoDBiEOG091G0OAC.
PhylomeDBiQ96LM6.
TreeFamiTF337872.

Family and domain databases

InterProiView protein in InterPro
IPR029361. TEX37.
PfamiView protein in Pfam
PF15217. TSC21. 1 hit.

Sequencei

Sequence statusi: Complete.

Q96LM6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGVKYPGQD PVDLDIYQSS HMVDYQPYRK HKYSRVTPQE QAKLDAQLRD
60 70 80 90 100
KEFYRPIPNP NPKLTDGYPA FKRPHMTAKD LGLPGFFPSQ EHEATREDER
110 120 130 140 150
KFTSTCHFTY PASHDLHLAQ GDPNQVLQSA DFPCLVDPKH QPAAEMAKGY
160 170 180
LLLPGCPCLH CHIVKVPILN RWGPLMPFYQ
Length:180
Mass (Da):20,615
Last modified:December 1, 2001 - v1
Checksum:iAB9BC8BFE2850E92
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_03514224D → N. Corresponds to variant dbSNP:rs35750657Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK058098 mRNA. Translation: BAB71663.1.
AC104134 Genomic DNA. Translation: AAY24330.1.
CH471215 Genomic DNA. Translation: EAW77070.1.
BC029522 mRNA. Translation: AAH29522.1.
CCDSiCCDS2003.1.
RefSeqiNP_689883.1. NM_152670.2.
XP_005264245.3. XM_005264188.3.
XP_011530993.1. XM_011532691.1.
XP_011530994.1. XM_011532692.1.
UniGeneiHs.132104.

Genome annotation databases

EnsembliENST00000303254; ENSP00000307142; ENSG00000172073.
GeneIDi200523.
KEGGihsa:200523.
UCSCiuc002stb.3. human.

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiTEX37_HUMAN
AccessioniPrimary (citable) accession number: Q96LM6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 2, 2007
Last sequence update: December 1, 2001
Last modified: June 7, 2017
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations