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Protein

Testis-expressed sequence 37 protein

Gene

TEX37

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Testis-expressed sequence 37 protein
Alternative name(s):
Testis-specific conserved protein of 21 kDa
Gene namesi
Name:TEX37
Synonyms:C2orf51, TSC21
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 2

Organism-specific databases

EuPathDBiHostDB:ENSG00000172073.3
HGNCiHGNC:26341 TEX37
neXtProtiNX_Q96LM6

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000172073
PharmGKBiPA162379191

Polymorphism and mutation databases

BioMutaiTEX37

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003049891 – 180Testis-expressed sequence 37 proteinAdd BLAST180

Proteomic databases

PaxDbiQ96LM6
PeptideAtlasiQ96LM6
PRIDEiQ96LM6
ProteomicsDBi77226

PTM databases

iPTMnetiQ96LM6
PhosphoSitePlusiQ96LM6

Expressioni

Tissue specificityi

Testis-specific (PubMed:17091336, PubMed:26168773). Detected in the germ cell lineage at all stages (PubMed:26168773).2 Publications

Gene expression databases

BgeeiENSG00000172073
CleanExiHS_C2orf51
ExpressionAtlasiQ96LM6 baseline and differential
GenevisibleiQ96LM6 HS

Organism-specific databases

HPAiHPA043987

Interactioni

Binary interactionsi

Show more details

Protein-protein interaction databases

BioGridi128332, 10 interactors
IntActiQ96LM6, 42 interactors
STRINGi9606.ENSP00000307142

Structurei

3D structure databases

ProteinModelPortaliQ96LM6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410J9TU Eukaryota
ENOG411193C LUCA
GeneTreeiENSGT00390000012177
HOGENOMiHOG000154692
HOVERGENiHBG108602
InParanoidiQ96LM6
OMAiYLLLPGC
OrthoDBiEOG091G0OAC
PhylomeDBiQ96LM6
TreeFamiTF337872

Family and domain databases

InterProiView protein in InterPro
IPR029361 TEX37
PANTHERiPTHR36882 PTHR36882, 1 hit
PfamiView protein in Pfam
PF15217 TSC21, 1 hit

Sequencei

Sequence statusi: Complete.

Q96LM6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGVKYPGQD PVDLDIYQSS HMVDYQPYRK HKYSRVTPQE QAKLDAQLRD
60 70 80 90 100
KEFYRPIPNP NPKLTDGYPA FKRPHMTAKD LGLPGFFPSQ EHEATREDER
110 120 130 140 150
KFTSTCHFTY PASHDLHLAQ GDPNQVLQSA DFPCLVDPKH QPAAEMAKGY
160 170 180
LLLPGCPCLH CHIVKVPILN RWGPLMPFYQ
Length:180
Mass (Da):20,615
Last modified:December 1, 2001 - v1
Checksum:iAB9BC8BFE2850E92
GO

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_03514224D → N. Corresponds to variant dbSNP:rs35750657Ensembl.1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK058098 mRNA Translation: BAB71663.1
AC104134 Genomic DNA Translation: AAY24330.1
CH471215 Genomic DNA Translation: EAW77070.1
BC029522 mRNA Translation: AAH29522.1
CCDSiCCDS2003.1
RefSeqiNP_689883.1, NM_152670.2
XP_005264245.3, XM_005264188.3
XP_011530993.1, XM_011532691.1
XP_011530994.1, XM_011532692.1
UniGeneiHs.132104

Genome annotation databases

EnsembliENST00000303254; ENSP00000307142; ENSG00000172073
GeneIDi200523
KEGGihsa:200523
UCSCiuc002stb.3 human

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Entry informationi

Entry nameiTEX37_HUMAN
AccessioniPrimary (citable) accession number: Q96LM6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 2, 2007
Last sequence update: December 1, 2001
Last modified: June 20, 2018
This is version 115 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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