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Q96LM6

- TEX37_HUMAN

UniProt

Q96LM6 - TEX37_HUMAN

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Protein
Testis-expressed sequence 37 protein
Gene
TEX37, C2orf51, TSC21
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Testis-expressed sequence 37 protein
Alternative name(s):
Testis-specific conserved protein of 21 kDa
Gene namesi
Name:TEX37
Synonyms:C2orf51, TSC21
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 2

Organism-specific databases

HGNCiHGNC:26341. TEX37.

Subcellular locationi

Nucleus By similarity

GO - Cellular componenti

  1. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA162379191.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 180180Testis-expressed sequence 37 protein
PRO_0000304989Add
BLAST

Proteomic databases

PaxDbiQ96LM6.
PRIDEiQ96LM6.

PTM databases

PhosphoSiteiQ96LM6.

Expressioni

Tissue specificityi

Testis-specific.1 Publication

Gene expression databases

BgeeiQ96LM6.
CleanExiHS_C2orf51.
GenevestigatoriQ96LM6.

Organism-specific databases

HPAiHPA043987.

Interactioni

Protein-protein interaction databases

BioGridi128332. 4 interactions.
IntActiQ96LM6. 3 interactions.
MINTiMINT-1456070.
STRINGi9606.ENSP00000307142.

Structurei

3D structure databases

ProteinModelPortaliQ96LM6.

Family & Domainsi

Phylogenomic databases

eggNOGiNOG41061.
HOGENOMiHOG000154692.
HOVERGENiHBG108602.
InParanoidiQ96LM6.
OMAiNRWGPLM.
OrthoDBiEOG7RZ5RG.
PhylomeDBiQ96LM6.
TreeFamiTF337872.

Family and domain databases

InterProiIPR029361. TEX37.
[Graphical view]
PfamiPF15217. TSC21. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q96LM6-1 [UniParc]FASTAAdd to Basket

« Hide

MAGVKYPGQD PVDLDIYQSS HMVDYQPYRK HKYSRVTPQE QAKLDAQLRD    50
KEFYRPIPNP NPKLTDGYPA FKRPHMTAKD LGLPGFFPSQ EHEATREDER 100
KFTSTCHFTY PASHDLHLAQ GDPNQVLQSA DFPCLVDPKH QPAAEMAKGY 150
LLLPGCPCLH CHIVKVPILN RWGPLMPFYQ 180
Length:180
Mass (Da):20,615
Last modified:December 1, 2001 - v1
Checksum:iAB9BC8BFE2850E92
GO

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti24 – 241D → N.
Corresponds to variant rs35750657 [ dbSNP | Ensembl ].
VAR_035142

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK058098 mRNA. Translation: BAB71663.1.
AC104134 Genomic DNA. Translation: AAY24330.1.
CH471215 Genomic DNA. Translation: EAW77070.1.
BC029522 mRNA. Translation: AAH29522.1.
CCDSiCCDS2003.1.
RefSeqiNP_689883.1. NM_152670.2.
XP_005264245.1. XM_005264188.1.
XP_006712027.1. XM_006711964.1.
UniGeneiHs.132104.

Genome annotation databases

EnsembliENST00000303254; ENSP00000307142; ENSG00000172073.
GeneIDi200523.
KEGGihsa:200523.
UCSCiuc002stb.2. human.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK058098 mRNA. Translation: BAB71663.1 .
AC104134 Genomic DNA. Translation: AAY24330.1 .
CH471215 Genomic DNA. Translation: EAW77070.1 .
BC029522 mRNA. Translation: AAH29522.1 .
CCDSi CCDS2003.1.
RefSeqi NP_689883.1. NM_152670.2.
XP_005264245.1. XM_005264188.1.
XP_006712027.1. XM_006711964.1.
UniGenei Hs.132104.

3D structure databases

ProteinModelPortali Q96LM6.
ModBasei Search...

Protein-protein interaction databases

BioGridi 128332. 4 interactions.
IntActi Q96LM6. 3 interactions.
MINTi MINT-1456070.
STRINGi 9606.ENSP00000307142.

PTM databases

PhosphoSitei Q96LM6.

Proteomic databases

PaxDbi Q96LM6.
PRIDEi Q96LM6.

Protocols and materials databases

DNASUi 200523.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000303254 ; ENSP00000307142 ; ENSG00000172073 .
GeneIDi 200523.
KEGGi hsa:200523.
UCSCi uc002stb.2. human.

Organism-specific databases

CTDi 200523.
GeneCardsi GC02P088825.
HGNCi HGNC:26341. TEX37.
HPAi HPA043987.
neXtProti NX_Q96LM6.
PharmGKBi PA162379191.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG41061.
HOGENOMi HOG000154692.
HOVERGENi HBG108602.
InParanoidi Q96LM6.
OMAi NRWGPLM.
OrthoDBi EOG7RZ5RG.
PhylomeDBi Q96LM6.
TreeFami TF337872.

Miscellaneous databases

ChiTaRSi C2orf51. human.
GenomeRNAii 200523.
NextBioi 89932.
PROi Q96LM6.

Gene expression databases

Bgeei Q96LM6.
CleanExi HS_C2orf51.
Genevestigatori Q96LM6.

Family and domain databases

InterProi IPR029361. TEX37.
[Graphical view ]
Pfami PF15217. TSC21. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Testis.
  2. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
    Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
    , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
    Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Testis.
  5. "Identification and characteristics of a novel testis-specific gene, Tsc21, in mice and human."
    Yu Z., Tang A., Gui Y., Guo X., Zhu H., Long Y., Li Z., Cai Z.
    Mol. Biol. Rep. 34:127-134(2007) [PubMed] [Europe PMC] [Abstract]
    Cited for: TISSUE SPECIFICITY.

Entry informationi

Entry nameiTEX37_HUMAN
AccessioniPrimary (citable) accession number: Q96LM6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 2, 2007
Last sequence update: December 1, 2001
Last modified: July 9, 2014
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 2
    Human chromosome 2: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations

External Data

Dasty 3

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