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Q96LM6

- TEX37_HUMAN

UniProt

Q96LM6 - TEX37_HUMAN

Protein

Testis-expressed sequence 37 protein

Gene

TEX37

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 89 (01 Oct 2014)
      Sequence version 1 (01 Dec 2001)
      Previous versions | rss
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    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Testis-expressed sequence 37 protein
    Alternative name(s):
    Testis-specific conserved protein of 21 kDa
    Gene namesi
    Name:TEX37
    Synonyms:C2orf51, TSC21
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 2

    Organism-specific databases

    HGNCiHGNC:26341. TEX37.

    Subcellular locationi

    Nucleus By similarity

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Nucleus

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA162379191.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 180180Testis-expressed sequence 37 proteinPRO_0000304989Add
    BLAST

    Proteomic databases

    PaxDbiQ96LM6.
    PRIDEiQ96LM6.

    PTM databases

    PhosphoSiteiQ96LM6.

    Expressioni

    Tissue specificityi

    Testis-specific.1 Publication

    Gene expression databases

    BgeeiQ96LM6.
    CleanExiHS_C2orf51.
    GenevestigatoriQ96LM6.

    Organism-specific databases

    HPAiHPA043987.

    Interactioni

    Protein-protein interaction databases

    BioGridi128332. 4 interactions.
    IntActiQ96LM6. 3 interactions.
    MINTiMINT-1456070.
    STRINGi9606.ENSP00000307142.

    Structurei

    3D structure databases

    ProteinModelPortaliQ96LM6.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    eggNOGiNOG41061.
    HOGENOMiHOG000154692.
    HOVERGENiHBG108602.
    InParanoidiQ96LM6.
    OMAiNRWGPLM.
    OrthoDBiEOG7RZ5RG.
    PhylomeDBiQ96LM6.
    TreeFamiTF337872.

    Family and domain databases

    InterProiIPR029361. TEX37.
    [Graphical view]
    PfamiPF15217. TSC21. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q96LM6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAGVKYPGQD PVDLDIYQSS HMVDYQPYRK HKYSRVTPQE QAKLDAQLRD    50
    KEFYRPIPNP NPKLTDGYPA FKRPHMTAKD LGLPGFFPSQ EHEATREDER 100
    KFTSTCHFTY PASHDLHLAQ GDPNQVLQSA DFPCLVDPKH QPAAEMAKGY 150
    LLLPGCPCLH CHIVKVPILN RWGPLMPFYQ 180
    Length:180
    Mass (Da):20,615
    Last modified:December 1, 2001 - v1
    Checksum:iAB9BC8BFE2850E92
    GO

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti24 – 241D → N.
    Corresponds to variant rs35750657 [ dbSNP | Ensembl ].
    VAR_035142

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK058098 mRNA. Translation: BAB71663.1.
    AC104134 Genomic DNA. Translation: AAY24330.1.
    CH471215 Genomic DNA. Translation: EAW77070.1.
    BC029522 mRNA. Translation: AAH29522.1.
    CCDSiCCDS2003.1.
    RefSeqiNP_689883.1. NM_152670.2.
    XP_005264245.1. XM_005264188.1.
    XP_006712027.1. XM_006711964.1.
    UniGeneiHs.132104.

    Genome annotation databases

    EnsembliENST00000303254; ENSP00000307142; ENSG00000172073.
    GeneIDi200523.
    KEGGihsa:200523.
    UCSCiuc002stb.2. human.

    Keywords - Coding sequence diversityi

    Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK058098 mRNA. Translation: BAB71663.1 .
    AC104134 Genomic DNA. Translation: AAY24330.1 .
    CH471215 Genomic DNA. Translation: EAW77070.1 .
    BC029522 mRNA. Translation: AAH29522.1 .
    CCDSi CCDS2003.1.
    RefSeqi NP_689883.1. NM_152670.2.
    XP_005264245.1. XM_005264188.1.
    XP_006712027.1. XM_006711964.1.
    UniGenei Hs.132104.

    3D structure databases

    ProteinModelPortali Q96LM6.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 128332. 4 interactions.
    IntActi Q96LM6. 3 interactions.
    MINTi MINT-1456070.
    STRINGi 9606.ENSP00000307142.

    PTM databases

    PhosphoSitei Q96LM6.

    Proteomic databases

    PaxDbi Q96LM6.
    PRIDEi Q96LM6.

    Protocols and materials databases

    DNASUi 200523.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000303254 ; ENSP00000307142 ; ENSG00000172073 .
    GeneIDi 200523.
    KEGGi hsa:200523.
    UCSCi uc002stb.2. human.

    Organism-specific databases

    CTDi 200523.
    GeneCardsi GC02P088825.
    HGNCi HGNC:26341. TEX37.
    HPAi HPA043987.
    neXtProti NX_Q96LM6.
    PharmGKBi PA162379191.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG41061.
    HOGENOMi HOG000154692.
    HOVERGENi HBG108602.
    InParanoidi Q96LM6.
    OMAi NRWGPLM.
    OrthoDBi EOG7RZ5RG.
    PhylomeDBi Q96LM6.
    TreeFami TF337872.

    Miscellaneous databases

    ChiTaRSi C2orf51. human.
    GenomeRNAii 200523.
    NextBioi 89932.
    PROi Q96LM6.

    Gene expression databases

    Bgeei Q96LM6.
    CleanExi HS_C2orf51.
    Genevestigatori Q96LM6.

    Family and domain databases

    InterProi IPR029361. TEX37.
    [Graphical view ]
    Pfami PF15217. TSC21. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Testis.
    2. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
      , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
      Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Testis.
    5. "Identification and characteristics of a novel testis-specific gene, Tsc21, in mice and human."
      Yu Z., Tang A., Gui Y., Guo X., Zhu H., Long Y., Li Z., Cai Z.
      Mol. Biol. Rep. 34:127-134(2007) [PubMed] [Europe PMC] [Abstract]
      Cited for: TISSUE SPECIFICITY.

    Entry informationi

    Entry nameiTEX37_HUMAN
    AccessioniPrimary (citable) accession number: Q96LM6
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 2, 2007
    Last sequence update: December 1, 2001
    Last modified: October 1, 2014
    This is version 89 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 2
      Human chromosome 2: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations

    External Data

    Dasty 3