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Q96LM5

- CD045_HUMAN

UniProt

Q96LM5 - CD045_HUMAN

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Protein

Uncharacterized protein C4orf45

Gene

C4orf45

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein C4orf45
Gene namesi
Name:C4orf45
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 4

Organism-specific databases

HGNCiHGNC:26342. C4orf45.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA162379953.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 186186Uncharacterized protein C4orf45PRO_0000325755Add
BLAST

Proteomic databases

PaxDbiQ96LM5.
PRIDEiQ96LM5.

PTM databases

PhosphoSiteiQ96LM5.

Expressioni

Gene expression databases

BgeeiQ96LM5.
CleanExiHS_C4orf45.
GenevestigatoriQ96LM5.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000412215.

Structurei

3D structure databases

ProteinModelPortaliQ96LM5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiNOG75666.
GeneTreeiENSGT00390000012736.
HOGENOMiHOG000074185.
HOVERGENiHBG107627.
InParanoidiQ96LM5.
OMAiKTGDLRY.
OrthoDBiEOG7NPFVG.
PhylomeDBiQ96LM5.
TreeFamiTF329701.

Family and domain databases

InterProiIPR027814. DUF4562.
[Graphical view]
PfamiPF15123. DUF4562. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q96LM5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MASVSYQKPT STTVGKQMIF TGPDYIKDYL PKIHQHTSYV GEQHLALEKT
60 70 80 90 100
GDLRYLWRPA SNRSLPAKYK HEYVSEIGWR IPQYNFINKS RLGSGFHIKY
110 120 130 140 150
EELSQASLDS ITHRYQNPWQ PKPHVLDMQG KQSRASFAWH MSAFEDTDQR
160 170 180
NSKWAILVRQ CKSSLPRASK PPKLPKLPKK EKKRKH
Length:186
Mass (Da):21,723
Last modified:May 18, 2010 - v3
Checksum:i5DF02D604613DF2B
GO

Sequence cautioni

The sequence BAB71665.1 differs from that shown. Reason: Frameshift at position 178.

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti72 – 721E → K in BAB71665. (PubMed:14702039)Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti46 – 461A → V.
Corresponds to variant rs17037864 [ dbSNP | Ensembl ].
VAR_039901
Natural varianti75 – 751S → G.1 Publication
Corresponds to variant rs662473 [ dbSNP | Ensembl ].
VAR_039902
Natural varianti84 – 841Y → C.
Corresponds to variant rs17037858 [ dbSNP | Ensembl ].
VAR_039903
Natural varianti93 – 931G → E.1 Publication
Corresponds to variant rs619128 [ dbSNP | Ensembl ].
VAR_039904
Natural varianti134 – 1341R → H.
Corresponds to variant rs10517695 [ dbSNP | Ensembl ].
VAR_039905

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK058100 mRNA. Translation: BAB71665.1. Frameshift.
AC093700 Genomic DNA. No translation available.
AC109823 Genomic DNA. No translation available.
CCDSiCCDS47156.1.
RefSeqiNP_689756.2. NM_152543.2.
UniGeneiHs.415576.

Genome annotation databases

EnsembliENST00000434826; ENSP00000412215; ENSG00000164123.
GeneIDi152940.
KEGGihsa:152940.
UCSCiuc003iqf.1. human.

Polymorphism databases

DMDMi296439413.

Keywords - Coding sequence diversityi

Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK058100 mRNA. Translation: BAB71665.1 . Frameshift.
AC093700 Genomic DNA. No translation available.
AC109823 Genomic DNA. No translation available.
CCDSi CCDS47156.1.
RefSeqi NP_689756.2. NM_152543.2.
UniGenei Hs.415576.

3D structure databases

ProteinModelPortali Q96LM5.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 9606.ENSP00000412215.

PTM databases

PhosphoSitei Q96LM5.

Polymorphism databases

DMDMi 296439413.

Proteomic databases

PaxDbi Q96LM5.
PRIDEi Q96LM5.

Protocols and materials databases

DNASUi 152940.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000434826 ; ENSP00000412215 ; ENSG00000164123 .
GeneIDi 152940.
KEGGi hsa:152940.
UCSCi uc003iqf.1. human.

Organism-specific databases

CTDi 152940.
GeneCardsi GC04M159814.
HGNCi HGNC:26342. C4orf45.
neXtProti NX_Q96LM5.
PharmGKBi PA162379953.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG75666.
GeneTreei ENSGT00390000012736.
HOGENOMi HOG000074185.
HOVERGENi HBG107627.
InParanoidi Q96LM5.
OMAi KTGDLRY.
OrthoDBi EOG7NPFVG.
PhylomeDBi Q96LM5.
TreeFami TF329701.

Miscellaneous databases

GenomeRNAii 152940.
NextBioi 87059.

Gene expression databases

Bgeei Q96LM5.
CleanExi HS_C4orf45.
Genevestigatori Q96LM5.

Family and domain databases

InterProi IPR027814. DUF4562.
[Graphical view ]
Pfami PF15123. DUF4562. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANTS GLY-75 AND GLU-93.
    Tissue: Testis.
  2. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
    Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
    , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
    Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiCD045_HUMAN
AccessioniPrimary (citable) accession number: Q96LM5
Secondary accession number(s): A8MPU3, C9J0T8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: May 18, 2010
Last modified: October 29, 2014
This is version 62 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 4
    Human chromosome 4: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations

External Data

Dasty 3