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Q96LM5

- CD045_HUMAN

UniProt

Q96LM5 - CD045_HUMAN

Protein

Uncharacterized protein C4orf45

Gene

C4orf45

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 61 (01 Oct 2014)
      Sequence version 3 (18 May 2010)
      Previous versions | rss
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    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Uncharacterized protein C4orf45
    Gene namesi
    Name:C4orf45
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 4

    Organism-specific databases

    HGNCiHGNC:26342. C4orf45.

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA162379953.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 186186Uncharacterized protein C4orf45PRO_0000325755Add
    BLAST

    Proteomic databases

    PaxDbiQ96LM5.
    PRIDEiQ96LM5.

    PTM databases

    PhosphoSiteiQ96LM5.

    Expressioni

    Gene expression databases

    BgeeiQ96LM5.
    CleanExiHS_C4orf45.
    GenevestigatoriQ96LM5.

    Interactioni

    Protein-protein interaction databases

    STRINGi9606.ENSP00000412215.

    Structurei

    3D structure databases

    ProteinModelPortaliQ96LM5.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    eggNOGiNOG75666.
    HOGENOMiHOG000074185.
    HOVERGENiHBG107627.
    OMAiKTGDLRY.
    OrthoDBiEOG7NPFVG.
    PhylomeDBiQ96LM5.
    TreeFamiTF329701.

    Family and domain databases

    InterProiIPR027814. DUF4562.
    [Graphical view]
    PfamiPF15123. DUF4562. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q96LM5-1 [UniParc]FASTAAdd to Basket

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    MASVSYQKPT STTVGKQMIF TGPDYIKDYL PKIHQHTSYV GEQHLALEKT    50
    GDLRYLWRPA SNRSLPAKYK HEYVSEIGWR IPQYNFINKS RLGSGFHIKY 100
    EELSQASLDS ITHRYQNPWQ PKPHVLDMQG KQSRASFAWH MSAFEDTDQR 150
    NSKWAILVRQ CKSSLPRASK PPKLPKLPKK EKKRKH 186
    Length:186
    Mass (Da):21,723
    Last modified:May 18, 2010 - v3
    Checksum:i5DF02D604613DF2B
    GO

    Sequence cautioni

    The sequence BAB71665.1 differs from that shown. Reason: Frameshift at position 178.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti72 – 721E → K in BAB71665. (PubMed:14702039)Curated

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti46 – 461A → V.
    Corresponds to variant rs17037864 [ dbSNP | Ensembl ].
    VAR_039901
    Natural varianti75 – 751S → G.1 Publication
    Corresponds to variant rs662473 [ dbSNP | Ensembl ].
    VAR_039902
    Natural varianti84 – 841Y → C.
    Corresponds to variant rs17037858 [ dbSNP | Ensembl ].
    VAR_039903
    Natural varianti93 – 931G → E.1 Publication
    Corresponds to variant rs619128 [ dbSNP | Ensembl ].
    VAR_039904
    Natural varianti134 – 1341R → H.
    Corresponds to variant rs10517695 [ dbSNP | Ensembl ].
    VAR_039905

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK058100 mRNA. Translation: BAB71665.1. Frameshift.
    AC093700 Genomic DNA. No translation available.
    AC109823 Genomic DNA. No translation available.
    CCDSiCCDS47156.1.
    RefSeqiNP_689756.2. NM_152543.2.
    UniGeneiHs.415576.

    Genome annotation databases

    EnsembliENST00000434826; ENSP00000412215; ENSG00000164123.
    GeneIDi152940.
    KEGGihsa:152940.
    UCSCiuc003iqf.1. human.

    Polymorphism databases

    DMDMi296439413.

    Keywords - Coding sequence diversityi

    Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK058100 mRNA. Translation: BAB71665.1 . Frameshift.
    AC093700 Genomic DNA. No translation available.
    AC109823 Genomic DNA. No translation available.
    CCDSi CCDS47156.1.
    RefSeqi NP_689756.2. NM_152543.2.
    UniGenei Hs.415576.

    3D structure databases

    ProteinModelPortali Q96LM5.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 9606.ENSP00000412215.

    PTM databases

    PhosphoSitei Q96LM5.

    Polymorphism databases

    DMDMi 296439413.

    Proteomic databases

    PaxDbi Q96LM5.
    PRIDEi Q96LM5.

    Protocols and materials databases

    DNASUi 152940.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000434826 ; ENSP00000412215 ; ENSG00000164123 .
    GeneIDi 152940.
    KEGGi hsa:152940.
    UCSCi uc003iqf.1. human.

    Organism-specific databases

    CTDi 152940.
    GeneCardsi GC04M159814.
    HGNCi HGNC:26342. C4orf45.
    neXtProti NX_Q96LM5.
    PharmGKBi PA162379953.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG75666.
    HOGENOMi HOG000074185.
    HOVERGENi HBG107627.
    OMAi KTGDLRY.
    OrthoDBi EOG7NPFVG.
    PhylomeDBi Q96LM5.
    TreeFami TF329701.

    Miscellaneous databases

    GenomeRNAii 152940.
    NextBioi 87059.

    Gene expression databases

    Bgeei Q96LM5.
    CleanExi HS_C4orf45.
    Genevestigatori Q96LM5.

    Family and domain databases

    InterProi IPR027814. DUF4562.
    [Graphical view ]
    Pfami PF15123. DUF4562. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], VARIANTS GLY-75 AND GLU-93.
      Tissue: Testis.
    2. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
      , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
      Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

    Entry informationi

    Entry nameiCD045_HUMAN
    AccessioniPrimary (citable) accession number: Q96LM5
    Secondary accession number(s): A8MPU3, C9J0T8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 18, 2008
    Last sequence update: May 18, 2010
    Last modified: October 1, 2014
    This is version 61 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 4
      Human chromosome 4: entries, gene names and cross-references to MIM
    2. Human entries with polymorphisms or disease mutations
      List of human entries with polymorphisms or disease mutations
    3. Human polymorphisms and disease mutations
      Index of human polymorphisms and disease mutations

    External Data

    Dasty 3