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Protein

UBX domain-containing protein 10

Gene

UBXN10

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Enzyme and pathway databases

BioCyciZFISH:ENSG00000162543-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
UBX domain-containing protein 10
Alternative name(s):
UBX domain-containing protein 3
Gene namesi
Name:UBXN10
Synonyms:UBXD3
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

HGNCiHGNC:26354. UBXN10.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000162543.
PharmGKBiPA162408337.

Polymorphism and mutation databases

BioMutaiUBXN10.
DMDMi55976757.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002110291 – 280UBX domain-containing protein 10Add BLAST280

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei87PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ96LJ8.
PaxDbiQ96LJ8.
PeptideAtlasiQ96LJ8.
PRIDEiQ96LJ8.

PTM databases

iPTMnetiQ96LJ8.
PhosphoSitePlusiQ96LJ8.

Expressioni

Gene expression databases

BgeeiENSG00000162543.
CleanExiHS_UBXN10.
GenevisibleiQ96LJ8. HS.

Organism-specific databases

HPAiHPA028555.
HPA028564.

Interactioni

Protein-protein interaction databases

BioGridi126082. 39 interactors.
IntActiQ96LJ8. 4 interactors.
MINTiMINT-8417727.
STRINGi9606.ENSP00000364240.

Structurei

3D structure databases

ProteinModelPortaliQ96LJ8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini194 – 271UBXPROSITE-ProRule annotationAdd BLAST78

Sequence similaritiesi

Contains 1 UBX domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG410IGEF. Eukaryota.
ENOG410XTZS. LUCA.
GeneTreeiENSGT00390000012939.
HOGENOMiHOG000231750.
HOVERGENiHBG056934.
InParanoidiQ96LJ8.
OMAiIETMEVP.
OrthoDBiEOG091G0GZJ.
PhylomeDBiQ96LJ8.
TreeFamiTF335927.

Family and domain databases

InterProiIPR029071. Ubiquitin-rel_dom.
IPR001012. UBX_dom.
[Graphical view]
PfamiPF00789. UBX. 1 hit.
[Graphical view]
SMARTiSM00166. UBX. 1 hit.
[Graphical view]
SUPFAMiSSF54236. SSF54236. 1 hit.
PROSITEiPS50033. UBX. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q96LJ8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATEAPVNIA PPECSTVVST AVDSLIWQPN SLNMHMIRPK SAKGRTRPSL
60 70 80 90 100
QKSQGVEVCA HHIPSPPPAI PYELPSSQKP GACAPKSPNQ GASDEIPELQ
110 120 130 140 150
QQVPTGASSS LNKYPVLPSI NRKNLEEEAV ETVAKKASSL QLSSIRALYQ
160 170 180 190 200
DETGTMKTSE EDSRARACAV ERKFIVRTKK QGSSRAGNLE EPSDQEPRLL
210 220 230 240 250
LAVRSPTGQR FVRHFRPTDD LQTIVAVAEQ KNKTSYRHCS IETMEVPRRR
260 270 280
FSDLTKSLQE CRIPHKSVLG ISLEDGEGWP
Length:280
Mass (Da):30,811
Last modified:December 1, 2001 - v1
Checksum:iA0B5D24C7F01F947
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK058158 mRNA. Translation: BAB71693.1.
Z98257 Genomic DNA. Translation: CAI20259.1.
CH471134 Genomic DNA. Translation: EAW94920.1.
BC047428 mRNA. Translation: AAH47428.1.
CCDSiCCDS205.1.
RefSeqiNP_689589.1. NM_152376.4.
XP_005245799.1. XM_005245742.3.
XP_011539001.1. XM_011540699.2.
UniGeneiHs.432503.

Genome annotation databases

EnsembliENST00000375099; ENSP00000364240; ENSG00000162543.
GeneIDi127733.
KEGGihsa:127733.
UCSCiuc001bdb.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK058158 mRNA. Translation: BAB71693.1.
Z98257 Genomic DNA. Translation: CAI20259.1.
CH471134 Genomic DNA. Translation: EAW94920.1.
BC047428 mRNA. Translation: AAH47428.1.
CCDSiCCDS205.1.
RefSeqiNP_689589.1. NM_152376.4.
XP_005245799.1. XM_005245742.3.
XP_011539001.1. XM_011540699.2.
UniGeneiHs.432503.

3D structure databases

ProteinModelPortaliQ96LJ8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi126082. 39 interactors.
IntActiQ96LJ8. 4 interactors.
MINTiMINT-8417727.
STRINGi9606.ENSP00000364240.

PTM databases

iPTMnetiQ96LJ8.
PhosphoSitePlusiQ96LJ8.

Polymorphism and mutation databases

BioMutaiUBXN10.
DMDMi55976757.

Proteomic databases

EPDiQ96LJ8.
PaxDbiQ96LJ8.
PeptideAtlasiQ96LJ8.
PRIDEiQ96LJ8.

Protocols and materials databases

DNASUi127733.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000375099; ENSP00000364240; ENSG00000162543.
GeneIDi127733.
KEGGihsa:127733.
UCSCiuc001bdb.4. human.

Organism-specific databases

CTDi127733.
GeneCardsiUBXN10.
HGNCiHGNC:26354. UBXN10.
HPAiHPA028555.
HPA028564.
neXtProtiNX_Q96LJ8.
OpenTargetsiENSG00000162543.
PharmGKBiPA162408337.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiENOG410IGEF. Eukaryota.
ENOG410XTZS. LUCA.
GeneTreeiENSGT00390000012939.
HOGENOMiHOG000231750.
HOVERGENiHBG056934.
InParanoidiQ96LJ8.
OMAiIETMEVP.
OrthoDBiEOG091G0GZJ.
PhylomeDBiQ96LJ8.
TreeFamiTF335927.

Enzyme and pathway databases

BioCyciZFISH:ENSG00000162543-MONOMER.

Miscellaneous databases

GenomeRNAii127733.
PROiQ96LJ8.

Gene expression databases

BgeeiENSG00000162543.
CleanExiHS_UBXN10.
GenevisibleiQ96LJ8. HS.

Family and domain databases

InterProiIPR029071. Ubiquitin-rel_dom.
IPR001012. UBX_dom.
[Graphical view]
PfamiPF00789. UBX. 1 hit.
[Graphical view]
SMARTiSM00166. UBX. 1 hit.
[Graphical view]
SUPFAMiSSF54236. SSF54236. 1 hit.
PROSITEiPS50033. UBX. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiUBX10_HUMAN
AccessioniPrimary (citable) accession number: Q96LJ8
Secondary accession number(s): Q5R386
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 23, 2004
Last sequence update: December 1, 2001
Last modified: November 2, 2016
This is version 96 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.